Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   C0J00_RS07905 Genome accession   NZ_CP025536
Coordinates   1555652..1556953 (-) Length   433 a.a.
NCBI ID   WP_104968354.1    Uniprot ID   A0A2L0D5B9
Organism   Streptococcus pluranimalium strain TH11417     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1550652..1561953
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C0J00_RS07895 (C0J00_07900) hpf 1554364..1554912 (-) 549 WP_104968352.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  C0J00_RS07900 (C0J00_07905) - 1554993..1555655 (-) 663 WP_104968353.1 ComF family protein -
  C0J00_RS07905 (C0J00_07910) comFA/cflA 1555652..1556953 (-) 1302 WP_104968354.1 DEAD/DEAH box helicase Machinery gene
  C0J00_RS07910 (C0J00_07915) - 1557000..1557629 (+) 630 WP_104968355.1 YigZ family protein -
  C0J00_RS07915 (C0J00_07920) cysK 1557727..1558656 (+) 930 WP_104968356.1 cysteine synthase A -
  C0J00_RS07925 (C0J00_07930) tnpA 1558809..1559320 (-) 512 Protein_1512 IS200/IS605 family transposase -
  C0J00_RS07930 (C0J00_07935) - 1559484..1559843 (-) 360 WP_104968357.1 S1 RNA-binding domain-containing protein -
  C0J00_RS10680 (C0J00_07940) - 1559843..1561243 (-) 1401 WP_104968358.1 Cof-type HAD-IIB family hydrolase -
  C0J00_RS07940 (C0J00_07945) - 1561291..1561929 (-) 639 WP_104968359.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49256.12 Da        Isoelectric Point: 9.5925

>NTDB_id=262364 C0J00_RS07905 WP_104968354.1 1555652..1556953(-) (comFA/cflA) [Streptococcus pluranimalium strain TH11417]
MKTLKEKSGCWFAGSSITAEEREEAIKIPAFTQENGNLTCNRCSEKITTDWQLPDGTRYCRSCILLGRLTEDEHLYYFPP
KTFPKRNALQWKGKLTSYQKEISGSLVQSLEDRKDSLVHAVTGAGKTEMIYEVVARVIDEGGQVCLASPRIDVCIELYKR
LSKDFSCDIDLLHGDSEPYSGSPLIIATTHQLLKFYHSFDLILVDEVDAFPYVDNKILYHAVRTAKKADGLTIYMTATST
EELDKQVKKGILKKRTLSRRFHGNPLIEPRNIWLTGLEKKVDSGKIPLKLKRYLERQFQTGYPLLIFVPDIAFGKKIKKV
LCRQYPKVSIGFVSSNSPDRLEEVEMFRHGDLRVLISTTILERGVTFLKVDVFVLLAHHKLFTSSSLIQIGGRVGRSLER
PTGDLLFFHEGLTRAIKKTKKEIRQMNNLGGFK

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=262364 C0J00_RS07905 WP_104968354.1 1555652..1556953(-) (comFA/cflA) [Streptococcus pluranimalium strain TH11417]
ATGAAAACGCTAAAAGAAAAAAGTGGTTGCTGGTTTGCAGGTTCTAGTATCACGGCAGAGGAAAGAGAAGAAGCCATAAA
GATACCTGCTTTCACTCAAGAAAATGGGAATCTTACTTGTAATAGATGTTCAGAAAAGATTACAACTGACTGGCAGTTGC
CGGATGGGACACGTTATTGTCGCTCCTGTATTTTATTAGGTAGATTGACGGAAGATGAACATCTCTATTATTTTCCACCG
AAAACTTTCCCAAAAAGAAATGCTTTACAATGGAAAGGCAAATTAACTAGTTATCAAAAAGAAATTTCAGGTAGTCTCGT
GCAATCACTTGAGGATAGAAAGGATAGTTTGGTACATGCCGTAACAGGAGCTGGAAAAACGGAAATGATCTATGAAGTAG
TCGCTCGAGTGATTGATGAAGGTGGACAAGTTTGTTTGGCCAGTCCTCGTATAGATGTTTGTATTGAATTATACAAGCGA
CTCAGCAAGGATTTTTCTTGTGATATTGATTTGTTACATGGTGATTCTGAACCATATAGTGGCTCCCCTTTGATTATTGC
AACTACCCATCAGCTGTTAAAGTTTTACCACTCTTTTGATCTTATATTAGTTGATGAAGTAGATGCCTTTCCCTACGTCG
ATAATAAGATACTTTATCATGCTGTTAGAACAGCGAAAAAAGCAGATGGTCTAACCATCTATATGACAGCAACTTCGACA
GAAGAATTAGATAAACAAGTCAAAAAAGGAATCTTAAAAAAACGAACTTTATCGCGAAGATTTCATGGGAATCCCTTAAT
TGAACCACGGAATATTTGGCTAACTGGACTGGAGAAAAAGGTTGACTCTGGTAAGATACCATTGAAACTAAAACGATATC
TAGAGAGGCAATTTCAAACAGGCTACCCGCTTTTAATTTTTGTACCAGATATTGCTTTTGGAAAGAAAATAAAGAAAGTT
CTTTGTCGACAATATCCCAAAGTTTCTATAGGTTTTGTCTCTAGTAATAGTCCAGATAGATTAGAAGAAGTAGAAATGTT
CAGACATGGTGATTTAAGAGTTCTCATATCAACGACAATTTTAGAAAGAGGAGTGACATTTCTTAAAGTGGATGTCTTTG
TTTTACTAGCTCATCATAAATTATTTACTAGCTCTAGTCTTATTCAGATAGGTGGTCGAGTAGGACGGTCATTAGAGAGA
CCGACAGGAGATCTACTCTTCTTTCATGAAGGGCTTACAAGGGCTATCAAAAAGACTAAAAAAGAAATTCGACAGATGAA
TAATTTGGGAGGCTTCAAGTGA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-238)

Helicase conserved C-terminal domain (Helicase_C)

(297-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2L0D5B9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

58.796

99.769

0.587
  comFA/cflA Streptococcus pneumoniae D39

58.796

99.769

0.587
  comFA/cflA Streptococcus pneumoniae R6

58.796

99.769

0.587
  comFA/cflA Streptococcus pneumoniae TIGR4

58.796

99.769

0.587
  comFA/cflA Streptococcus mitis NCTC 12261

58.333

99.769

0.582
  comFA/cflA Streptococcus mitis SK321

57.407

99.769

0.573
  comFA Lactococcus lactis subsp. cremoris KW2

47.319

99.076

0.469
  comFA Bacillus subtilis subsp. subtilis str. 168

37.327

100

0.374
  comFA Latilactobacillus sakei subsp. sakei 23K

38.67

93.764

0.363

Multiple sequence alignment