Detailed information NTG0262361

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: C0J00_RS07335
• Genome accession: NZ_CP025536
• Coordinates: 1450171..1452387 (-)
• Length: 738 a.a.
• NCBI ID: WP_104968861.1
• Uniprot ID: A0A2L0D7B6
• Organism: Streptococcus pluranimalium strain TH11417
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1445171..1457387

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C0J00_RS07315 (C0J00_07320)	-	1445560..1446651 (-)	1092	WP_104968261.1	sensor histidine kinase	-
C0J00_RS07320 (C0J00_07325)	-	1446651..1447382 (-)	732	WP_104968262.1	ABC transporter permease	-
C0J00_RS07325 (C0J00_07330)	-	1447366..1448262 (-)	897	WP_104968263.1	ABC transporter ATP-binding protein	-
C0J00_RS07330 (C0J00_07335)	-	1448513..1450048 (-)	1536	WP_104968264.1	AMP-binding protein	-
C0J00_RS07335 (C0J00_07340)	comEC/celB	1450171..1452387 (-)	2217	WP_104968861.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
C0J00_RS07340 (C0J00_07345)	-	1452395..1453066 (-)	672	WP_104968265.1	helix-hairpin-helix domain-containing protein	-
C0J00_RS07345 (C0J00_07350)	-	1453137..1453886 (-)	750	WP_104968266.1	lysophospholipid acyltransferase family protein	-
C0J00_RS07350 (C0J00_07355)	-	1454048..1454236 (+)	189	WP_104968267.1	hypothetical protein	-
C0J00_RS07355 (C0J00_07360)	-	1454592..1455125 (-)	534	WP_158667324.1	isoprenylcysteine carboxyl methyltransferase family protein	-
C0J00_RS07360 (C0J00_07365)	-	1455382..1456140 (+)	759	WP_104968268.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
C0J00_RS07365 (C0J00_07370)	-	1456137..1456397 (+)	261	WP_104968269.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 738 a.a.
• Molecular weight: 83756.51 Da
• Isoelectric Point: 9.5470

>NTDB_id=262361 C0J00_RS07335 WP_104968861.1 1450171..1452387(-) (comEC/celB) [Streptococcus pluranimalium strain TH11417]
MLKPIYLAFLVALTYFMILTKSWVVFLLALLAAIALFRQYSKKAIIQTIIILTLFVAYFTFLGNKQIQLEKQLPSQVSTL
RVIPDSISVDGDLLSARAEEGKQRYQLYYQLQTELEKEYFQNLNQLILLKVMASVEKPQGQRNFKGFDYKTYLKREGIYG
IVQVEKVNAIHTVAPQNPEEWVRLWRRKLLVHINQHFPEPMKHYMTGLLLGYLDKSFDEMSDIYTDLGIIHLFALSGMQV
GFFVGIFRTILLRLGLLREHFLYVLLPFSFIYAGLTGFTISVVRSLLQAILSQFGLRKWDNLGTTILILFLLSPHFLVTT
GGVLSFAYAFILSTIDLETLSGCRKAVVESMVLSLGILPLLVFYFGTFQPLSILLTAFFSVIFDVFLLPLLSLVLLASPI
VSLDFFNPCFYFLESVIKWTVHLSPRPLVFGSPNLTVLLLMLISLAVVHDFWHDKKLRYCFLIVVVALFAVTKKPLENEV
TVLDIGQGDSIFIRDIRGKTLLIDTGGRVDFTQKEEWRRRQKTANAERTSIPYLKSRGISSIDQLVITHTDADHMGDLAV
LAKQFSIKKVLVSPGALTNPSFVNELKSLKIKVGLLQAGDQIAIMGSSLRVLYPWDQGDGGNNDSLVLYGKLLDKRFLFT
GDLEVDGEKSLMMRYPNLPVDILKAGHHGSKGSSDPDFLKHIGAKVVLISAGLNNRYQHPNDETLERFEAEKMMVYRTDQ
EGAIRYRGVKTWKVETVR

Nucleotide

• Length: 2217 bp

>NTDB_id=262361 C0J00_RS07335 WP_104968861.1 1450171..1452387(-) (comEC/celB) [Streptococcus pluranimalium strain TH11417]
ATGTTAAAGCCAATCTATTTGGCTTTTTTAGTAGCTTTGACCTATTTTATGATCTTGACCAAATCCTGGGTTGTCTTTTT
GCTAGCTTTGCTTGCAGCTATCGCTTTATTCAGACAATATTCTAAAAAGGCAATTATACAGACGATTATTATCCTCACTC
TATTTGTTGCGTATTTTACTTTTTTGGGGAACAAGCAGATTCAGCTGGAAAAGCAGCTCCCAAGTCAAGTGTCGACCTTG
CGTGTAATACCTGATAGCATTTCTGTAGATGGTGACTTATTATCTGCGCGTGCTGAAGAAGGTAAGCAAAGGTATCAGCT
TTATTATCAATTACAGACGGAGTTGGAAAAGGAGTATTTTCAAAATCTTAATCAGCTGATCCTTTTAAAGGTAATGGCTT
CAGTCGAGAAGCCACAAGGTCAGCGCAATTTTAAAGGTTTTGATTATAAGACTTATTTGAAACGAGAAGGCATTTATGGG
ATCGTTCAAGTTGAGAAAGTCAACGCCATTCATACGGTTGCTCCTCAAAACCCAGAGGAATGGGTTAGACTGTGGCGGAG
AAAGCTTCTGGTCCACATCAATCAACACTTTCCTGAGCCTATGAAACATTATATGACGGGACTTTTGTTGGGGTATTTGG
ATAAGTCTTTTGACGAGATGAGTGATATCTATACGGATTTGGGGATTATTCATCTTTTTGCCCTGTCTGGCATGCAGGTG
GGCTTTTTTGTCGGTATTTTTCGGACGATCCTTTTACGTCTAGGGCTTTTGAGGGAGCATTTTTTGTATGTTCTTCTGCC
ATTTTCCTTTATTTACGCCGGTCTAACAGGATTCACGATTTCTGTGGTACGAAGCTTATTACAGGCCATTCTCAGTCAAT
TTGGCTTGCGAAAATGGGATAATTTAGGAACAACCATCTTGATATTGTTCCTGCTATCGCCCCATTTTTTGGTTACAACA
GGAGGTGTTCTATCTTTCGCTTATGCCTTCATACTGTCTACCATAGATTTAGAAACTTTGTCAGGATGCCGCAAAGCAGT
AGTAGAAAGTATGGTACTTTCACTAGGCATTCTACCCTTGTTGGTATTTTATTTCGGGACTTTTCAGCCTCTGTCAATTC
TTTTAACAGCATTCTTTTCAGTGATTTTTGATGTCTTTTTGTTACCCTTGTTAAGTCTTGTGTTATTAGCCAGTCCGATA
GTATCTCTAGACTTTTTTAATCCTTGCTTTTACTTTTTAGAATCAGTTATCAAGTGGACGGTACATCTGTCTCCTCGCCC
CTTGGTTTTTGGTAGCCCTAACTTAACTGTACTTCTATTAATGCTTATTTCTTTAGCTGTTGTACATGATTTTTGGCATG
ATAAAAAATTGAGGTACTGTTTTTTGATTGTTGTAGTTGCCTTGTTTGCTGTGACGAAAAAACCTTTAGAAAATGAGGTG
ACTGTTCTAGATATTGGGCAAGGAGATTCGATTTTCATTAGGGATATCAGAGGGAAAACCTTGCTTATTGATACGGGAGG
CCGAGTTGATTTTACTCAGAAAGAGGAGTGGCGCAGGCGGCAGAAAACAGCTAATGCTGAGCGGACGTCTATCCCCTATC
TGAAAAGTCGAGGGATTTCGTCCATCGACCAGCTTGTGATTACACACACTGATGCAGACCATATGGGAGATCTGGCAGTT
CTAGCCAAGCAGTTTAGTATTAAGAAAGTTTTGGTTAGTCCAGGTGCTCTGACCAATCCCTCTTTTGTAAACGAACTAAA
ATCATTAAAAATCAAAGTAGGCTTGCTTCAAGCTGGGGATCAGATTGCGATTATGGGGTCTTCTCTTCGAGTTCTCTACC
CGTGGGATCAGGGAGATGGTGGGAATAACGATTCCTTGGTCTTGTATGGAAAGTTATTAGATAAGCGATTTCTTTTTACG
GGAGATTTAGAAGTTGATGGCGAAAAATCCTTGATGATGAGATATCCTAACTTACCCGTTGATATTTTAAAAGCTGGTCA
CCATGGCTCTAAAGGATCCTCTGACCCAGACTTTTTAAAACATATCGGAGCAAAAGTCGTTTTGATTTCAGCTGGTCTTA
ATAATCGTTACCAGCATCCCAATGATGAAACCTTAGAACGCTTTGAGGCAGAAAAGATGATGGTTTATAGGACCGATCAA
GAAGGAGCGATTCGTTACAGAGGTGTAAAGACTTGGAAAGTTGAAACGGTTCGTTGA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (208-452)

• Metallo-beta-lactamase superfamily (Lactamase_B) (486-690)

• Domain of unknown function (DUF4131) (DUF4131) (22-168)

3D structure

• AlphaFold DB: A0A2L0D7B6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	48.982	99.864	0.489
comEC/celB	Streptococcus mitis SK321	48.645	100	0.486
comEC/celB	Streptococcus pneumoniae TIGR4	47.561	100	0.476
comEC/celB	Streptococcus pneumoniae Rx1	47.425	100	0.474
comEC/celB	Streptococcus pneumoniae D39	47.425	100	0.474
comEC/celB	Streptococcus pneumoniae R6	47.425	100	0.474
comEC	Lactococcus lactis subsp. cremoris KW2	43.876	100	0.442