Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   C0J00_RS01950 Genome accession   NZ_CP025536
Coordinates   383019..383708 (+) Length   229 a.a.
NCBI ID   WP_104967318.1    Uniprot ID   A0A2L0D2B6
Organism   Streptococcus pluranimalium strain TH11417     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 378019..388708
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C0J00_RS01925 (C0J00_01925) - 378397..379068 (-) 672 WP_104967313.1 potassium channel family protein -
  C0J00_RS01930 (C0J00_01930) - 379087..380460 (-) 1374 WP_104967314.1 TrkH family potassium uptake protein -
  C0J00_RS01935 (C0J00_01935) rsmG 380485..381198 (-) 714 WP_104967315.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  C0J00_RS01940 (C0J00_01940) htpX 381313..382218 (+) 906 WP_104967316.1 zinc metalloprotease HtpX -
  C0J00_RS01945 (C0J00_01945) - 382253..382786 (+) 534 WP_104967317.1 YceD family protein -
  C0J00_RS01950 (C0J00_01950) covR 383019..383708 (+) 690 WP_104967318.1 response regulator transcription factor Regulator
  C0J00_RS01955 (C0J00_01955) - 383752..385209 (+) 1458 WP_233995856.1 HAMP domain-containing histidine kinase -
  C0J00_RS01960 (C0J00_01960) nrdR 385652..386125 (+) 474 WP_104968798.1 transcriptional regulator NrdR -
  C0J00_RS01965 (C0J00_01965) - 386125..387297 (+) 1173 WP_104967320.1 DnaD domain protein -
  C0J00_RS01970 (C0J00_01970) dnaI 387300..388202 (+) 903 WP_104967321.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26329.13 Da        Isoelectric Point: 4.7749

>NTDB_id=262341 C0J00_RS01950 WP_104967318.1 383019..383708(+) (covR) [Streptococcus pluranimalium strain TH11417]
MTKSILIIEDEKNLSRFVSLELQHEGYSVTIESNGRAGLETALDKDFDLILLDLMLPEMDGFEVTRRLQQEKSTYIIMMT
ARDSVMDIVSGLDRGADDYIIKPFAIEELLARVRAAFRRQEIEESKRNASGGASYRDLKLDPQNRSVVRGDETVPLTKRE
FDLLSALMSNMNRVMTREELLNLVWKYDEAVETNVVDVYIRYLRGKIDVSGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=262341 C0J00_RS01950 WP_104967318.1 383019..383708(+) (covR) [Streptococcus pluranimalium strain TH11417]
ATGACAAAAAGTATTCTGATCATAGAGGATGAGAAAAATCTTTCGCGCTTCGTTTCTTTAGAATTACAGCATGAAGGGTA
TTCGGTAACCATTGAAAGTAATGGTCGCGCTGGTTTAGAAACAGCATTAGATAAAGATTTTGATTTGATTTTATTAGACT
TGATGTTGCCAGAGATGGATGGCTTTGAAGTGACACGTCGCTTACAACAAGAAAAGTCAACTTATATCATTATGATGACT
GCTAGAGACTCTGTTATGGATATTGTTTCAGGATTGGATCGTGGCGCAGATGATTATATTATCAAGCCATTTGCGATTGA
GGAACTCTTAGCGCGTGTTCGTGCTGCTTTTCGTCGTCAAGAAATTGAAGAAAGTAAACGAAATGCTTCAGGTGGAGCTA
GCTATCGTGACCTCAAATTGGATCCACAGAATCGCTCGGTTGTTCGCGGGGATGAAACAGTTCCTTTAACAAAACGTGAG
TTTGATTTGTTATCTGCTTTGATGTCTAACATGAACCGTGTCATGACACGTGAAGAATTATTAAATCTTGTCTGGAAGTA
TGATGAAGCTGTAGAAACAAATGTTGTTGATGTCTACATTCGTTATCTTCGTGGCAAAATTGATGTCTCTGGTAAAGAAT
CATACATTCAAACTGTCCGTGGTATGGGTTATGTCATTCGTGAAAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2L0D2B6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

81.223

100

0.812
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.544

99.563

0.672
  vicR Streptococcus mutans UA159

44.156

100

0.445
  micA Streptococcus pneumoniae Cp1015

42.308

100

0.432

Multiple sequence alignment