Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   CR922_RS07770 Genome accession   NZ_CP025400
Coordinates   1461124..1461813 (-) Length   229 a.a.
NCBI ID   WP_101361342.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain EPS     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1456124..1466813
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CR922_RS07750 dnaI 1456931..1457833 (-) 903 WP_002946786.1 primosomal protein DnaI -
  CR922_RS07755 - 1457837..1459012 (-) 1176 WP_101361340.1 DnaD domain protein -
  CR922_RS07760 nrdR 1459009..1459488 (-) 480 WP_101361341.1 transcriptional regulator NrdR -
  CR922_RS07765 covS 1459610..1461127 (-) 1518 WP_059257356.1 HAMP domain-containing sensor histidine kinase Regulator
  CR922_RS07770 covR 1461124..1461813 (-) 690 WP_101361342.1 response regulator transcription factor Regulator
  CR922_RS07775 - 1461969..1462505 (-) 537 WP_041826965.1 DUF177 domain-containing protein -
  CR922_RS07780 rsmG 1462802..1463515 (+) 714 WP_002946490.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  CR922_RS07785 - 1463585..1464949 (+) 1365 WP_082302294.1 TrkH family potassium uptake protein -
  CR922_RS07790 - 1464989..1465660 (+) 672 WP_101361343.1 potassium channel family protein -
  CR922_RS10430 - 1465677..1465847 (-) 171 Protein_1452 ascorbate 6-phosphate lactonase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26628.70 Da        Isoelectric Point: 4.6354

>NTDB_id=261000 CR922_RS07770 WP_101361342.1 1461124..1461813(-) (covR) [Streptococcus thermophilus strain EPS]
MSKRILIVEDERNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQETDTYIMMMT
ARDSIMDIVAGLDRGADDYIIKPFAIEELLARIRATFRRQDIEATKKAPAKASTYRDLKLDVQNRAVVRGDEVIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDVIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIRER

Nucleotide


Download         Length: 690 bp        

>NTDB_id=261000 CR922_RS07770 WP_101361342.1 1461124..1461813(-) (covR) [Streptococcus thermophilus strain EPS]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAGAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCGGACAACGGACGCGAAGGACTTGAAATGGCACTTGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTCGAAGTGACACGTCGTCTCCAACAAGAAACAGATACTTATATTATGATGATGACA
GCTCGCGACTCAATCATGGATATTGTTGCTGGTTTGGATCGTGGAGCTGATGACTATATTATAAAACCATTTGCGATTGA
AGAACTGTTGGCACGTATTCGTGCAACCTTCCGTCGTCAAGATATCGAAGCTACTAAGAAGGCACCAGCTAAAGCGTCAA
CCTATCGCGATTTAAAATTAGATGTTCAAAACCGTGCAGTTGTTCGCGGTGATGAGGTAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTAAGCAATATGAACCAAGTAATGACCCGTGAGGAACTCTTGCTTCAAGTCTGGAAATA
TGATGACGTAATTGAAACAAACGTTGTAGATGTTTATATTCGTTACTTACGTGGGAAAATCGACATTCCAGGTAAGGAAT
CATACATTCAAACAGTACGAGGGATGGGTTACGTTATCCGTGAAAGATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

95.633

100

0.956
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.105

99.563

0.668
  vicR Streptococcus mutans UA159

45.259

100

0.459
  micA Streptococcus pneumoniae Cp1015

43.913

100

0.441

Multiple sequence alignment