Detailed information NTG0260263

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: DRF63_RS10700
• Genome accession: NZ_CP030753
• Coordinates: 2242617..2243291 (-)
• Length: 224 a.a.
• NCBI ID: WP_208622122.1
• Uniprot ID: -
• Organism: Actinobacillus pleuropneumoniae strain S4074
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2237617..2248291

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DRF63_RS10670 (DRF63_10660)	adhP	2237719..2238768 (+)	1050	WP_005602862.1	alcohol dehydrogenase AdhP	-
DRF63_RS10675 (DRF63_10665)	miaA	2238900..2239844 (+)	945	WP_005618608.1	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	-
DRF63_RS10680 (DRF63_10670)	hfq	2239909..2240187 (+)	279	WP_005599741.1	RNA chaperone Hfq	-
DRF63_RS10685 (DRF63_10675)	hflX	2240225..2241586 (+)	1362	WP_080550267.1	ribosome rescue GTPase HflX	-
DRF63_RS10690 (DRF63_10680)	-	2241622..2242182 (-)	561	WP_005599745.1	TIGR00730 family Rossman fold protein	-
DRF63_RS10695 (DRF63_10685)	-	2242245..2242568 (+)	324	WP_005599746.1	MazG nucleotide pyrophosphohydrolase domain-containing protein	-
DRF63_RS10700 (DRF63_10690)	crp	2242617..2243291 (-)	675	WP_208622122.1	cAMP-activated global transcriptional regulator CRP	Regulator
DRF63_RS10705 (DRF63_10695)	-	2243369..2243587 (-)	219	WP_005599748.1	YheU family protein	-
DRF63_RS10710 (DRF63_10700)	slmA	2243593..2244201 (-)	609	WP_005620316.1	nucleoid occlusion factor SlmA	-
DRF63_RS10715 (DRF63_10705)	dut	2244307..2244762 (-)	456	WP_005599752.1	dUTP diphosphatase	-
DRF63_RS10720 (DRF63_10710)	coaBC	2244771..2245976 (-)	1206	WP_005602882.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
DRF63_RS10725 (DRF63_10715)	radC	2246184..2246846 (+)	663	WP_005599756.1	RadC family protein	Machinery gene
DRF63_RS10730 (DRF63_10720)	rpmB	2247015..2247251 (+)	237	WP_005599762.1	50S ribosomal protein L28	-
DRF63_RS10735 (DRF63_10725)	rpmG	2247263..2247433 (+)	171	WP_005599764.1	50S ribosomal protein L33	-
DRF63_RS11160	-	2247559..2247777 (+)	219	WP_162031030.1	hypothetical protein	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25205.06 Da
• Isoelectric Point: 6.4067

>NTDB_id=260263 DRF63_RS10700 WP_208622122.1 2242617..2243291(-) (crp) [Actinobacillus pleuropneumoniae strain S4074]
MQDISISTPQLDSELSAPSIHDPAVEWFLTHCHIHRYPSKYTLIHAGEDAESLFYIVSGSVAVFIKDEEGKEMILSHLGQ
GEFVDEISLFEDTIQPRTAWVKTKGACEIAEISYKKFKQLVHLNPDILMYLSAQMARRLRQTSRQVSNLAFLDVTGRIAQ
TLMNLAKMPDAMTHPEGMQIKITRQEIGQMVGCSRETVGRILKMLEDEGLISAHGKTIVVYGTR

Nucleotide

• Length: 675 bp

>NTDB_id=260263 DRF63_RS10700 WP_208622122.1 2242617..2243291(-) (crp) [Actinobacillus pleuropneumoniae strain S4074]
ATGCAAGATATTTCAATTTCAACACCTCAGCTAGACAGTGAGCTGTCCGCCCCGTCTATTCATGATCCGGCGGTGGAATG
GTTTCTGACTCACTGTCATATTCATCGTTATCCGTCAAAATATACGCTTATTCATGCGGGTGAGGATGCCGAATCATTAT
TCTATATCGTCAGCGGCTCCGTTGCAGTGTTTATTAAAGATGAAGAAGGGAAAGAAATGATCCTTTCTCACCTCGGTCAA
GGTGAATTTGTCGATGAAATCAGCTTATTTGAAGACACTATTCAACCGCGTACCGCTTGGGTCAAAACCAAAGGCGCTTG
CGAAATTGCGGAAATCTCGTATAAAAAATTCAAACAGCTTGTGCATTTAAATCCGGATATTCTTATGTATCTTTCCGCGC
AAATGGCTCGCCGCCTACGCCAAACCTCACGCCAAGTAAGTAACCTCGCTTTCTTAGACGTAACCGGTCGTATCGCACAA
ACCTTAATGAATTTGGCGAAAATGCCGGATGCGATGACCCATCCGGAAGGAATGCAAATTAAGATTACCCGCCAAGAAAT
CGGTCAAATGGTCGGTTGTTCTCGAGAAACGGTCGGTAGAATCTTAAAAATGCTAGAAGATGAAGGCTTAATTTCAGCAC
ACGGTAAAACCATTGTCGTTTATGGCACTCGCTAA

Domains

Predicted by InterProScan.

• Cyclic nucleotide-binding domain (cNMP_binding) (36-121)

• Crp-like helix-turn-helix domain (HTH_Crp_2) (156-220)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Vibrio cholerae strain A1552	76.847	90.625	0.696
crp	Haemophilus influenzae Rd KW20	73.399	90.625	0.665
crp	Acinetobacter baumannii D1279779	45.327	95.536	0.433