Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   CXP43_RS05875 Genome accession   NZ_CP025308
Coordinates   1135712..1136368 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain Lzh-a42     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1130712..1141368
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CXP43_RS05850 (CXP43_05850) oppF 1131242..1132159 (+) 918 WP_014417419.1 oligopeptide ABC transporter ATP-binding protein OppF -
  CXP43_RS05855 (CXP43_05855) - 1132266..1133462 (+) 1197 WP_014417420.1 putative glycoside hydrolase -
  CXP43_RS05860 (CXP43_05860) - 1133571..1134149 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  CXP43_RS05865 (CXP43_05865) spx 1134328..1134723 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  CXP43_RS05870 (CXP43_05870) - 1134780..1135436 (-) 657 WP_014417421.1 TerC family protein -
  CXP43_RS05875 (CXP43_05875) mecA 1135712..1136368 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  CXP43_RS05880 (CXP43_05880) - 1136520..1137680 (+) 1161 WP_014417422.1 competence protein CoiA family protein -
  CXP43_RS05885 (CXP43_05885) pepF 1137908..1139737 (+) 1830 WP_003155028.1 oligoendopeptidase F Regulator
  CXP43_RS21585 - 1139775..1139942 (-) 168 WP_003155026.1 hypothetical protein -
  CXP43_RS05890 (CXP43_05890) spxH 1140229..1141131 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=259959 CXP43_RS05875 WP_003155032.1 1135712..1136368(+) (mecA) [Bacillus velezensis strain Lzh-a42]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=259959 CXP43_RS05875 WP_003155032.1 1135712..1136368(+) (mecA) [Bacillus velezensis strain Lzh-a42]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAAGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCAAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment