Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   DQ228_RS07095 Genome accession   NZ_CP030250
Coordinates   1384988..1385632 (-) Length   214 a.a.
NCBI ID   WP_002951384.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain CS20     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1379988..1390632
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQ228_RS07070 - 1382089..1383087 (-) 999 WP_011226284.1 NAD(P)/FAD-dependent oxidoreductase -
  DQ228_RS07075 trmD 1383089..1383808 (-) 720 WP_002951382.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  DQ228_RS07080 rimM 1383798..1384316 (-) 519 WP_011226286.1 ribosome maturation factor RimM -
  DQ228_RS07095 vraR 1384988..1385632 (-) 645 WP_002951384.1 response regulator transcription factor Regulator
  DQ228_RS07100 - 1385622..1386632 (-) 1011 WP_011226288.1 sensor histidine kinase -
  DQ228_RS07105 liaF 1386629..1387327 (-) 699 WP_084826070.1 cell wall-active antibiotics response protein LiaF -
  DQ228_RS07110 - 1387582..1387749 (-) 168 WP_014608530.1 potassium channel family protein -
  DQ228_RS07115 stkP/pknB 1388387..1390258 (-) 1872 WP_014621795.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24048.39 Da        Isoelectric Point: 4.5864

>NTDB_id=259538 DQ228_RS07095 WP_002951384.1 1384988..1385632(-) (vraR) [Streptococcus thermophilus strain CS20]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=259538 DQ228_RS07095 WP_002951384.1 1384988..1385632(-) (vraR) [Streptococcus thermophilus strain CS20]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGATCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTGGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTAAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCATGATAGTCACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACCGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379

Multiple sequence alignment