Detailed information NTG0259536

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: CXL14_RS06225
• Genome accession: NZ_CP025258
• Coordinates: 1215195..1216358 (+)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus sp. SJ-10
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1210195..1221358

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CXL14_RS06205	-	1210611..1211807 (+)	1197	WP_014419014.1	glycosyltransferase	-
CXL14_RS06210	-	1211940..1213016 (+)	1077	WP_003151382.1	MraY family glycosyltransferase	-
CXL14_RS06215	-	1213106..1214320 (-)	1215	WP_014419013.1	LCP family protein	-
CXL14_RS06220	-	1214325..1214972 (-)	648	WP_007614107.1	YigZ family protein	-
CXL14_RS06225	degS	1215195..1216358 (+)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
CXL14_RS06230	degU	1216435..1217124 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
CXL14_RS06235	-	1217222..1218070 (+)	849	WP_003151387.1	DegV family protein	-
CXL14_RS06240	comFA	1218178..1219563 (+)	1386	WP_014419012.1	DEAD/DEAH box helicase	Machinery gene
CXL14_RS06245	-	1219621..1219905 (+)	285	WP_014419011.1	competence protein ComFB	-
CXL14_RS06250	comFC	1219911..1220600 (+)	690	WP_197535984.1	ComF family protein	Machinery gene
CXL14_RS06255	-	1220674..1221093 (+)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=259536 CXL14_RS06225 WP_007407484.1 1215195..1216358(+) (degS) [Bacillus sp. SJ-10]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=259536 CXL14_RS06225 WP_007407484.1 1215195..1216358(+) (degS) [Bacillus sp. SJ-10]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGTCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCTGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951