Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   CXP32_RS09070 Genome accession   NZ_CP025256
Coordinates   1721312..1721971 (+) Length   219 a.a.
NCBI ID   WP_000565004.1    Uniprot ID   A0AA95DDC2
Organism   Streptococcus pneumoniae strain Xen35     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1716312..1726971
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CXP32_RS09030 (CXP32_09030) mgaSpn 1716468..1717949 (-) 1482 WP_001205280.1 virulence factor transcriptional regulator MgaSpn -
  CXP32_RS09035 (CXP32_09035) - 1718392..1718556 (+) 165 WP_001808603.1 GlsB/YeaQ/YmgE family stress response membrane protein -
  CXP32_RS09040 (CXP32_09040) amaP 1718640..1719206 (+) 567 WP_000030213.1 alkaline shock response membrane anchor protein AmaP -
  CXP32_RS09045 (CXP32_09045) - 1719218..1719388 (+) 171 WP_000455066.1 DUF2273 domain-containing protein -
  CXP32_RS09050 (CXP32_09050) - 1719427..1720035 (+) 609 WP_000064115.1 Asp23/Gls24 family envelope stress response protein -
  CXP32_RS09055 (CXP32_09055) - 1720066..1720269 (+) 204 WP_000109957.1 CsbD family protein -
  CXP32_RS09060 (CXP32_09060) - 1720379..1720618 (-) 240 WP_001005784.1 transposase -
  CXP32_RS09065 (CXP32_09065) - 1720796..1721242 (-) 447 WP_000155427.1 GNAT family N-acetyltransferase -
  CXP32_RS09070 (CXP32_09070) cclA/cilC 1721312..1721971 (+) 660 WP_000565004.1 A24 family peptidase Machinery gene
  CXP32_RS09075 (CXP32_09075) - 1722023..1723174 (-) 1152 WP_000481750.1 XRE family transcriptional regulator -
  CXP32_RS09080 (CXP32_09080) - 1723189..1723920 (-) 732 WP_000934018.1 hypothetical protein -
  CXP32_RS12115 (CXP32_09085) - 1724149..1724250 (+) 102 Protein_1709 prepilin peptidase -
  CXP32_RS09090 (CXP32_09090) trpA 1724222..1724998 (-) 777 WP_001126999.1 tryptophan synthase subunit alpha -
  CXP32_RS09095 (CXP32_09095) trpB 1724991..1726214 (-) 1224 WP_000331293.1 tryptophan synthase subunit beta -
  CXP32_RS09100 (CXP32_09100) - 1726192..1726791 (-) 600 WP_000169894.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24842.93 Da        Isoelectric Point: 7.6165

>NTDB_id=259473 CXP32_RS09070 WP_000565004.1 1721312..1721971(+) (cclA/cilC) [Streptococcus pneumoniae strain Xen35]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELSLG
LLFLLYSWGWLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFQLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=259473 CXP32_RS09070 WP_000565004.1 1721312..1721971(+) (cclA/cilC) [Streptococcus pneumoniae strain Xen35]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTAGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAATTAAGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGGATGGCTCTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCAGCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-88)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae TIGR4

100

100

1
  cclA/cilC Streptococcus pneumoniae Rx1

94.977

100

0.95
  cclA/cilC Streptococcus pneumoniae D39

94.977

100

0.95
  cclA/cilC Streptococcus pneumoniae R6

94.977

100

0.95
  cclA/cilC Streptococcus mitis SK321

91.781

100

0.918
  cclA/cilC Streptococcus mitis NCTC 12261

87.215

100

0.872

Multiple sequence alignment