Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   CVO91_RS05305 Genome accession   NZ_CP024974
Coordinates   1037756..1039135 (+) Length   459 a.a.
NCBI ID   WP_033875427.1    Uniprot ID   -
Organism   Streptococcus suis strain CZ130302     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1032756..1044135
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CVO91_RS05275 (CVO91_05275) pstA 1033220..1034107 (+) 888 WP_002940867.1 phosphate ABC transporter permease PstA -
  CVO91_RS05280 (CVO91_05280) pstB 1034132..1034935 (+) 804 WP_002940866.1 phosphate ABC transporter ATP-binding protein PstB -
  CVO91_RS05285 (CVO91_05285) pstB 1034947..1035705 (+) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  CVO91_RS05290 (CVO91_05290) phoU 1035734..1036390 (+) 657 WP_002940865.1 phosphate signaling complex protein PhoU -
  CVO91_RS05295 (CVO91_05295) - 1036540..1036947 (+) 408 WP_100664799.1 hypothetical protein -
  CVO91_RS05300 (CVO91_05300) ciaR 1037092..1037763 (+) 672 WP_002940863.1 response regulator transcription factor Regulator
  CVO91_RS05305 (CVO91_05305) ciaH 1037756..1039135 (+) 1380 WP_033875427.1 HAMP domain-containing sensor histidine kinase Regulator
  CVO91_RS05310 (CVO91_05310) - 1039236..1040465 (+) 1230 WP_002940861.1 transglutaminase domain-containing protein -
  CVO91_RS05315 (CVO91_05315) rpsT 1040718..1040966 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  CVO91_RS05320 (CVO91_05320) coaA 1041025..1041945 (-) 921 WP_002940857.1 type I pantothenate kinase -
  CVO91_RS05325 (CVO91_05325) - 1042054..1042644 (+) 591 WP_002940854.1 class I SAM-dependent methyltransferase -
  CVO91_RS05330 (CVO91_05330) - 1042641..1043918 (+) 1278 WP_002940851.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51886.62 Da        Isoelectric Point: 6.8976

>NTDB_id=256931 CVO91_RS05305 WP_033875427.1 1037756..1039135(+) (ciaH) [Streptococcus suis strain CZ130302]
MPKRLKKLMYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKEEPAMAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSMPVPKNQKNTRDVEQLKLGINTHVLLYSKSGEMVNPDTFTGLADLPLDKEKLGGIKEATVESSFGM
SEDYRYVTIELATDELGYYSSYDIKYATILVNVSQIKSSIETYESTVAIVMVSAWLISILASIYLSNLSIRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPEATILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGRIQITANIKDKSVYFTVADNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKTLGGKISVRDNQPKGTIFEVGLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=256931 CVO91_RS05305 WP_033875427.1 1037756..1039135(+) (ciaH) [Streptococcus suis strain CZ130302]
ATGCCTAAGCGATTAAAAAAATTAATGTACACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGTTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTATCAAAATTCAGATAATACCTTGAAACGGA
TTAAGGAAGAGCCAGCGATGGCTGTTGGTTTTGCAATCGCAAGAACCTATGAGCCTAACTCTGTCTTTATACTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCATGCCTGTTCCTAAAAATCAAAAAAATACTAGAGATGT
AGAACAGCTGAAATTAGGTATCAATACTCATGTCTTACTCTATAGTAAAAGTGGAGAAATGGTCAATCCAGATACTTTTA
CTGGTTTGGCCGACCTACCGTTAGATAAGGAAAAATTGGGCGGAATTAAGGAAGCAACGGTTGAATCAAGCTTCGGTATG
TCTGAAGATTATCGCTATGTGACGATTGAGCTGGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTAGTGAATGTCAGCCAAATAAAATCCTCCATTGAGACCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGCTCATTTCTATCTTGGCCAGTATTTACCTATCAAATCTTAGTATACGTCCGATTCTAATTAGCTATCAAAAGCAA
AAAGACTTTGTTGAAAATGCTAGTCATGAGTTGCGTACGCCGTTGGCTGTTCTCCAAAATCGCTTGGAGAGCCTGTTTCG
CCATCCCGAAGCGACGATTTTAGAGAGTAGTGAAAGCATCGGATCTAGTTTGGAAGAAGTTCGAAATATGCGATTATTGA
CAACGAACCTGCTCAATTTGGCTCGTCGTGATGATGGCTTAAAAGTTGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACACTAACAGTTAATAATTTGATTCATCAGCCGAT
TCGAACAGACAAGGTCTTGATTAAACAGTTGCTTACCATTTTATTTGACAATGCCATGAAGTATACCGATGATGATGGCA
GAATTCAAATTACAGCTAATATCAAGGATAAATCTGTCTACTTCACAGTTGCCGACAATGGTTTGGGAATCAGCGATGCC
GATAAGAAGAAAATCTTTGATCGCTTTTATCGAGTTGATAAGGCTAGAACGCGTCAAAAAGGTGGTTTCGGTCTAGGATT
ATCGCTGGCTCAGCAAATTATCAAGACACTAGGTGGGAAAATTTCTGTTAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTAGGATTACCTAAATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

50

99.782

0.499
  ciaH Streptococcus pneumoniae D39

50

99.782

0.499
  ciaH Streptococcus pneumoniae R6

50

99.782

0.499
  ciaH Streptococcus pneumoniae TIGR4

50

99.782

0.499
  ciaH Streptococcus mutans UA159

49.89

99.129

0.495

Multiple sequence alignment