Detailed information NTG0256585

Bioinformatically predicted

Overview

• Name: comB6
• Type: Machinery gene
• Locus tag: CV728_RS07685
• Genome accession: NZ_CP024948
• Coordinates: 1578698..1579753 (-)
• Length: 351 a.a.
• NCBI ID: WP_145818311.1
• Uniprot ID: A0A518YH77
• Organism: Helicobacter pylori strain B140
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1573698..1584753

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CV728_RS07660 (CV728_07680)	-	1574234..1575646 (-)	1413	WP_145818068.1	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	-
CV728_RS07665 (CV728_07685)	comB10	1575717..1576853 (-)	1137	WP_145818069.1	DNA type IV secretion system protein ComB10	Machinery gene
CV728_RS07670 (CV728_07690)	comB9	1576846..1577829 (-)	984	WP_145818070.1	TrbG/VirB9 family P-type conjugative transfer protein	Machinery gene
CV728_RS07675 (CV728_07695)	comB8	1577829..1578572 (-)	744	WP_128036478.1	virB8 family protein	Machinery gene
CV728_RS07680 (CV728_07700)	comB7	1578569..1578682 (-)	114	WP_001217873.1	hypothetical protein	Machinery gene
CV728_RS07685 (CV728_07705)	comB6	1578698..1579753 (-)	1056	WP_145818311.1	P-type conjugative transfer protein TrbL	Machinery gene
CV728_RS07690 (CV728_07710)	-	1579761..1580765 (-)	1005	WP_145818313.1	PDZ domain-containing protein	-
CV728_RS07695 (CV728_07715)	-	1580765..1581067 (-)	303	WP_145818071.1	YbaB/EbfC family nucleoid-associated protein	-
CV728_RS07700 (CV728_07720)	panD	1581070..1581423 (-)	354	WP_145818072.1	aspartate 1-decarboxylase	-
CV728_RS07705 (CV728_07725)	-	1581413..1583638 (-)	2226	WP_145818074.1	ATP-dependent Clp protease ATP-binding subunit	-
CV728_RS07710 (CV728_07730)	-	1583638..1583913 (-)	276	WP_000784903.1	ATP-dependent Clp protease adaptor ClpS	-
CV728_RS07715 (CV728_07735)	-	1583928..1584341 (-)	414	WP_001023005.1	universal stress protein	-

Sequence

Protein

• Length: 351 a.a.
• Molecular weight: 39730.72 Da
• Isoelectric Point: 8.8165

>NTDB_id=256585 CV728_RS07685 WP_145818311.1 1578698..1579753(-) (comB6) [Helicobacter pylori strain B140]
MKNDAYEIILSWFITPLTAILGRFAEFFLYTLHAQLVFNSVVALAFMLFAYRSLKEQNFFSASALLEALLFVGFFALFNY
ALKNPMHFYEFFQNAIFIAPNMITQSLSQSLSNFSNHALSLDFIFNHGFYALSFISDLSHNEMSVWLFLSILQALFLSIL
FAIIILVYLEVHVWCSLGVLFLAFGFFKTWRSVVVICLKKCFALGFYKPLLLLVGFLNVSVTKALIDAHMQEKQDLSLLL
VVALFLCCVSIIGVPFFINALFRVQNSLKETYKLATNLSANLSQNAFNSLQYITTPPAPSSVSTSTSGSVSKEKETHSPT
FKVETTQLDVKIPNFKQKKVKKDTINTKNEI

Nucleotide

• Length: 1056 bp

>NTDB_id=256585 CV728_RS07685 WP_145818311.1 1578698..1579753(-) (comB6) [Helicobacter pylori strain B140]
ATGAAAAATGACGCTTATGAGATTATCCTTTCTTGGTTTATCACGCCTCTCACGGCGATTTTAGGGCGTTTCGCTGAATT
TTTCCTCTACACCTTGCATGCACAATTGGTGTTTAATAGCGTGGTCGCTTTGGCGTTCATGCTCTTTGCTTATAGGAGTT
TGAAAGAACAGAATTTTTTCAGCGCTAGTGCGCTTTTAGAGGCGTTATTGTTTGTGGGGTTTTTTGCGCTTTTTAACTAC
GCTTTAAAAAATCCCATGCATTTTTATGAATTTTTCCAAAACGCTATTTTTATTGCGCCTAACATGATCACACAAAGCCT
CTCTCAAAGCTTGAGTAACTTTTCTAACCACGCGCTTTCTTTAGATTTTATCTTTAATCATGGTTTTTATGCCCTTAGTT
TCATCAGCGATTTGAGCCATAATGAAATGTCCGTGTGGCTTTTTTTAAGCATATTGCAAGCGCTTTTTTTGAGCATTCTG
TTTGCGATCATCATTTTAGTGTATTTAGAAGTGCATGTGTGGTGCTCTTTAGGGGTGCTGTTTTTAGCGTTTGGGTTTTT
TAAAACTTGGAGAAGCGTTGTGGTTATATGCCTAAAAAAATGCTTCGCTCTTGGGTTTTACAAGCCTCTTTTGTTGTTGG
TGGGGTTTTTGAATGTGTCGGTTACTAAGGCTTTAATAGACGCTCATATGCAAGAAAAACAAGACTTAAGCCTTTTATTA
GTGGTAGCGTTATTTTTGTGTTGCGTTTCTATCATAGGCGTGCCTTTTTTCATCAACGCTTTGTTTAGGGTGCAAAACAG
CCTTAAAGAAACTTACAAACTCGCTACCAATTTGAGCGCTAATCTCAGCCAAAACGCTTTCAATTCCTTACAATATATCA
CGACCCCACCCGCTCCCTCTAGCGTTTCTACTTCTACAAGCGGTAGCGTCTCTAAAGAAAAAGAAACGCATTCCCCCACA
TTTAAGGTAGAAACCACTCAATTAGATGTAAAAATCCCAAATTTCAAGCAAAAAAAGGTTAAAAAGGATACAATAAATAC
AAAAAATGAAATTTAA

Domains

Predicted by InterproScan.

• TrbL/VirB6 plasmid conjugal transfer protein (TrbL) (44-254)

3D structure

• AlphaFold DB: A0A518YH77

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB6	Helicobacter pylori 26695	96.296	100	0.963