Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   CV728_RS07675 Genome accession   NZ_CP024948
Coordinates   1577829..1578572 (-) Length   247 a.a.
NCBI ID   WP_128036478.1    Uniprot ID   A0A439BZV5
Organism   Helicobacter pylori strain B140     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1572829..1583572
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CV728_RS07655 (CV728_07675) gmd 1573034..1574179 (-) 1146 WP_145818067.1 GDP-mannose 4,6-dehydratase -
  CV728_RS07660 (CV728_07680) - 1574234..1575646 (-) 1413 WP_145818068.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  CV728_RS07665 (CV728_07685) comB10 1575717..1576853 (-) 1137 WP_145818069.1 DNA type IV secretion system protein ComB10 Machinery gene
  CV728_RS07670 (CV728_07690) comB9 1576846..1577829 (-) 984 WP_145818070.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  CV728_RS07675 (CV728_07695) comB8 1577829..1578572 (-) 744 WP_128036478.1 virB8 family protein Machinery gene
  CV728_RS07680 (CV728_07700) comB7 1578569..1578682 (-) 114 WP_001217873.1 hypothetical protein Machinery gene
  CV728_RS07685 (CV728_07705) comB6 1578698..1579753 (-) 1056 WP_145818311.1 P-type conjugative transfer protein TrbL Machinery gene
  CV728_RS07690 (CV728_07710) - 1579761..1580765 (-) 1005 WP_145818313.1 PDZ domain-containing protein -
  CV728_RS07695 (CV728_07715) - 1580765..1581067 (-) 303 WP_145818071.1 YbaB/EbfC family nucleoid-associated protein -
  CV728_RS07700 (CV728_07720) panD 1581070..1581423 (-) 354 WP_145818072.1 aspartate 1-decarboxylase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28810.02 Da        Isoelectric Point: 8.9604

>NTDB_id=256583 CV728_RS07675 WP_128036478.1 1577829..1578572(-) (comB8) [Helicobacter pylori strain B140]
MREKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALILAIVLISLLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
VQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLTNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APTNRND

Nucleotide


Download         Length: 744 bp        

>NTDB_id=256583 CV728_RS07675 WP_128036478.1 1577829..1578572(-) (comB8) [Helicobacter pylori strain B140]
ATGAGAGAAAAGCCTTTCAACAGCGAGCAGTTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTCAGACTAGAGAGAAACCGCTTGAAAATCGCTT
ACAAGCTCTTAGGCTTGATGAGTTTTATCGCTCTTATCTTAGCGATCGTGTTAATCAGTCTTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAGGTGTGGCAACGCTTTGAAGATTTGATTAAAACCCAAAACAGCATTTAT
GTGCAAAGCCATTTAGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
GTCCATTGCAGCTAAACTAACGAACGAAAACAAGCTGGTGTATGAAAAGCGTTATAAAATCGTATTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACTCGCTACAGCATCACTGAAATC
GCGCCGACTAACAGGAATGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A439BZV5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

98.785

100

0.988

Multiple sequence alignment