Detailed information NTG0256574

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: CV728_RS05700
• Genome accession: NZ_CP024948
• Coordinates: 1163398..1164198 (-)
• Length: 266 a.a.
• NCBI ID: WP_145817628.1
• Uniprot ID: A0A518YG37
• Organism: Helicobacter pylori strain B140
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1158398..1169198

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CV728_RS08715 (CV728_05665)	-	1159277..1160062 (-)	786	Protein_1087	hypothetical protein	-
CV728_RS05660 (CV728_05670)	-	1160062..1160448 (-)	387	WP_194151419.1	DUF1294 domain-containing protein	-
CV728_RS08940 (CV728_05680)	-	1160747..1161013 (-)	267	Protein_1089	lysozyme	-
CV728_RS05680 (CV728_05690)	-	1161433..1161993 (-)	561	WP_145817624.1	hypothetical protein	-
CV728_RS05685 (CV728_05695)	-	1161977..1162315 (-)	339	WP_101005683.1	hypothetical protein	-
CV728_RS05690 (CV728_05700)	-	1162500..1162859 (-)	360	WP_145817626.1	tetratricopeptide repeat protein	-
CV728_RS05695 (CV728_05705)	dprB	1162997..1163401 (-)	405	WP_000599237.1	Holliday junction resolvase RuvX	Machinery gene
CV728_RS05700 (CV728_05710)	dprA	1163398..1164198 (-)	801	WP_145817628.1	DNA-processing protein DprA	Machinery gene
CV728_RS05705 (CV728_05715)	minE	1164210..1164443 (-)	234	WP_145817631.1	cell division topological specificity factor MinE	-
CV728_RS05710 (CV728_05720)	minD	1164440..1165246 (-)	807	WP_145817632.1	septum site-determining protein MinD	-
CV728_RS05715 (CV728_05725)	ilvC	1165270..1166262 (-)	993	WP_145817634.1	ketol-acid reductoisomerase	-
CV728_RS05725 (CV728_05735)	-	1166511..1167293 (+)	783	WP_145817636.1	NAD+ synthase	-
CV728_RS05730 (CV728_05740)	-	1167290..1168228 (+)	939	WP_145817637.1	tetraacyldisaccharide 4'-kinase	-
CV728_RS05735 (CV728_05745)	pseH	1168161..1168703 (-)	543	WP_145817639.1	UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase	-

Sequence

Protein

• Length: 266 a.a.
• Molecular weight: 29882.75 Da
• Isoelectric Point: 8.2264

>NTDB_id=256574 CV728_RS05700 WP_145817628.1 1163398..1164198(-) (dprA) [Helicobacter pylori strain B140]
MKSNFQYSALENIPKAFDILKDHPKKLYCVGDTKLLEAPLKVAIIGTRRPTPYSKQHTITLARELAKNGAVIVSGGALGV
DIIAQENALPKTIMLSPCSLDFIYPTNNHKVIQEIAQNGLILSEYEKDFMPIKGSFLARNRLVIALSDAVIIPQADLQSG
SMSSARLAQKYQKPLFVLPQRLNESDGTNELLEKGQAQGIFNIQNFINTLLKDYHLKEMPEMKDEFLEYCAKNPSYEEAY
LKFGDKLLEYELLGKIKRINHLVVLA

Nucleotide

• Length: 801 bp

>NTDB_id=256574 CV728_RS05700 WP_145817628.1 1163398..1164198(-) (dprA) [Helicobacter pylori strain B140]
ATGAAAAGCAACTTCCAATACAGCGCGCTAGAAAATATCCCTAAAGCCTTTGACATTCTCAAAGACCACCCTAAAAAACT
CTATTGTGTGGGCGATACCAAGCTTTTAGAAGCGCCTTTAAAAGTGGCTATCATAGGCACAAGAAGACCCACCCCTTATA
GCAAGCAACACACCATCACTCTAGCCAGAGAGCTTGCTAAAAATGGCGCGGTTATTGTGAGCGGAGGAGCGTTAGGCGTG
GATATTATCGCTCAAGAAAACGCCTTGCCAAAAACGATCATGCTTTCGCCTTGCAGTTTGGATTTCATCTATCCTACGAA
CAATCATAAAGTGATCCAAGAAATCGCGCAAAACGGCTTGATTTTAAGCGAATATGAAAAAGACTTCATGCCCATTAAAG
GTTCTTTTTTAGCGAGAAACCGCCTGGTGATCGCTTTAAGCGATGCGGTCATTATCCCCCAAGCGGATTTACAAAGCGGC
TCTATGAGTAGCGCGAGATTAGCCCAAAAATACCAAAAGCCCTTATTTGTTTTGCCTCAGCGCTTGAATGAGAGCGATGG
CACTAATGAGCTTTTAGAAAAAGGGCAGGCTCAAGGGATATTTAATATTCAAAATTTTATAAACACCCTTTTAAAAGACT
ACCATTTAAAAGAAATGCCTGAAATGAAAGATGAATTTTTAGAATATTGCGCGAAAAACCCGAGCTATGAAGAGGCGTAT
CTCAAATTTGGGGATAAGCTTTTAGAATACGAGCTGTTGGGTAAGATCAAGCGCATCAATCATCTCGTGGTGTTAGCATG
A

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (12-197)

3D structure

• AlphaFold DB: A0A518YG37

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Helicobacter pylori 26695	96.617	100	0.966
dprA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	48.23	84.962	0.41