Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   CV729_RS01215 Genome accession   NZ_CP024947
Coordinates   241014..241751 (+) Length   245 a.a.
NCBI ID   WP_145731663.1    Uniprot ID   -
Organism   Helicobacter pylori strain J182     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 236014..246751
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CV729_RS01190 (CV729_01185) panD 238176..238526 (+) 351 WP_108593697.1 aspartate 1-decarboxylase -
  CV729_RS01195 (CV729_01190) - 238537..238830 (+) 294 WP_000347917.1 YbaB/EbfC family nucleoid-associated protein -
  CV729_RS01200 (CV729_01195) - 238830..239825 (+) 996 WP_145731660.1 PDZ domain-containing protein -
  CV729_RS01205 (CV729_01200) comB6 239833..240888 (+) 1056 WP_145731661.1 P-type conjugative transfer protein TrbL Machinery gene
  CV729_RS01210 (CV729_01205) comB7 240904..241017 (+) 114 WP_001217873.1 hypothetical protein Machinery gene
  CV729_RS01215 (CV729_01210) comB8 241014..241751 (+) 738 WP_145731663.1 virB8 family protein Machinery gene
  CV729_RS01220 (CV729_01215) comB9 241751..242737 (+) 987 WP_145731664.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  CV729_RS01225 (CV729_01220) comB10 242730..243866 (+) 1137 WP_145731666.1 DNA type IV secretion system protein ComB10 Machinery gene
  CV729_RS01230 (CV729_01225) - 243936..245348 (+) 1413 WP_145731668.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  CV729_RS01235 (CV729_01230) gmd 245377..246522 (+) 1146 WP_145731670.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28578.77 Da        Isoelectric Point: 9.2316

>NTDB_id=256555 CV729_RS01215 WP_145731663.1 241014..241751(+) (comB8) [Helicobacter pylori strain J182]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALVLAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEYLTKTQNSIY
TQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLLNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
TNRGD

Nucleotide


Download         Length: 738 bp        

>NTDB_id=256555 CV729_RS01215 WP_145731663.1 241014..241751(+) (comB8) [Helicobacter pylori strain J182]
ATGAAAGAAAAACCTTTCAATAGCGAGCAGTTGATCTATTTAGAAGAGCTTTTAAGCCATCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTCAGGCTGGAGAGAAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGCTTGATGAGTTTTATCGCTCTTGTTTTAGCGATCGTGTTAATCAGTGTTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAATATTTGACTAAAACCCAAAACAGCATTTAT
ACGCAAAGCCATTTAGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
CTCTATTGCAGCTAAACTTTTGAACGAAAACAAGCTAGTGTATGAAAAGCGTTATAAAATCGTGCTGAGTTATTTGTTTG
ACACCCCAGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACTCGTTACAGCATCACTGAAATC
ACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

96.356

100

0.971

Multiple sequence alignment