Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   CTW00_RS00170 Genome accession   NZ_CP024843
Coordinates   29769..30455 (-) Length   228 a.a.
NCBI ID   WP_037583387.1    Uniprot ID   -
Organism   Streptococcus iniae strain FP5228     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 24769..35455
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CTW00_RS00150 (CTW00_00031) dnaI 25565..26467 (-) 903 WP_003101664.1 primosomal protein DnaI -
  CTW00_RS00155 (CTW00_00032) - 26468..27655 (-) 1188 WP_100185161.1 DnaD domain protein -
  CTW00_RS00160 (CTW00_00033) nrdR 27639..28133 (-) 495 WP_003101666.1 transcriptional regulator NrdR -
  CTW00_RS00165 (CTW00_00034) - 28279..29766 (-) 1488 WP_037583389.1 HAMP domain-containing histidine kinase -
  CTW00_RS00170 (CTW00_00035) covR 29769..30455 (-) 687 WP_037583387.1 two-component system response regulator CovR Regulator
  CTW00_RS00175 (CTW00_00036) - 30684..31217 (-) 534 WP_003101669.1 DUF177 domain-containing protein -
  CTW00_RS00180 (CTW00_00037) htpX 31405..32301 (-) 897 WP_003101670.1 zinc metalloprotease HtpX -
  CTW00_RS00185 (CTW00_00038) - 32340..32897 (-) 558 WP_003101671.1 LemA family protein -
  CTW00_RS00190 (CTW00_00039) rsmG 33042..33758 (+) 717 WP_003101672.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  CTW00_RS00195 (CTW00_00040) ktrB 33850..35211 (+) 1362 WP_017794720.1 potassium uptake transporter channel subunit KtrB -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26743.67 Da        Isoelectric Point: 4.6541

>NTDB_id=255787 CTW00_RS00170 WP_037583387.1 29769..30455(-) (covR) [Streptococcus iniae strain FP5228]
MTKKILIVEDEKNLARFVSLELQHEGYEVTVEVNGREGLDTALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGWDRGADDYIVKPFAIEELLARIRAIFRRQDIETEKKSPNQGIYRDLVLNPQNRSVNRGDEEISLTKREY
DLLNILMSNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDMQGRESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=255787 CTW00_RS00170 WP_037583387.1 29769..30455(-) (covR) [Streptococcus iniae strain FP5228]
ATGACAAAAAAAATTCTAATTGTTGAAGATGAAAAAAATCTTGCAAGGTTTGTTTCATTAGAATTGCAACACGAAGGTTA
CGAAGTAACTGTAGAAGTGAATGGTCGTGAAGGACTTGACACAGCGCTTGAAAAAGATTTTGATTTAATCTTGCTTGATT
TGATGTTACCTGAAATGGATGGTTTTGAAGTGACCCGTCGTCTTCAAACTGAAAAAACAACCTACATTATGATGATGACA
GCACGCGATTCTATCATGGACGTGGTTGCTGGTTGGGATCGTGGTGCAGATGATTATATTGTTAAGCCATTTGCTATTGA
AGAATTATTGGCACGTATTCGTGCAATTTTCCGTCGTCAAGATATTGAAACTGAGAAAAAATCTCCTAATCAAGGTATTT
ACCGTGATTTAGTCTTAAATCCACAAAACCGTTCTGTAAACCGTGGAGATGAAGAAATTTCATTGACAAAACGCGAATAT
GATTTGTTAAACATTTTAATGAGCAATATGAATCGTGTCATGACGCGTGAAGAGTTGCTGTCAAATGTTTGGAAATACGA
TGAAGCTGTTGAAACAAACGTTGTTGACGTGTATATTCGTTACCTACGTGGAAAAATCGATATGCAAGGACGTGAGTCCT
ATATTCAAACTGTTCGTGGAATGGGATATGTTATTCGTGAGAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.096

100

0.825
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.079

99.561

0.658
  vicR Streptococcus mutans UA159

42.857

100

0.434
  micA Streptococcus pneumoniae Cp1015

42.609

100

0.43

Multiple sequence alignment