Detailed information NTG0254563

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: CPZ93_RS26580
• Genome accession: NZ_CP024630
• Coordinates: 5624169..5625506 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain PA59
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5619169..5630506

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CPZ93_RS26555 (CPZ93_27190)	pgeF	5619312..5620040 (-)	729	WP_003123393.1	peptidoglycan editing factor PgeF	-
CPZ93_RS26560 (CPZ93_27195)	rluD	5620037..5620999 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
CPZ93_RS26565 (CPZ93_27200)	-	5621145..5622170 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
CPZ93_RS26570 (CPZ93_27205)	-	5622354..5622572 (+)	219	WP_253942776.1	PP0621 family protein	-
CPZ93_RS26575 (CPZ93_27210)	pilS	5622562..5624154 (+)	1593	WP_003123394.1	two-component system sensor histidine kinase PilS	Regulator
CPZ93_RS26580 (CPZ93_27215)	pilR	5624169..5625506 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
CPZ93_RS26585 (CPZ93_27220)	thiO	5625552..5626646 (-)	1095	WP_003123395.1	glycine oxidase ThiO	-
CPZ93_RS26590 (CPZ93_27225)	-	5626781..5627290 (+)	510	WP_003102595.1	Tfp pilus assembly protein FimT/FimU	-
CPZ93_RS26595 (CPZ93_27230)	-	5627396..5627902 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
CPZ93_RS26600 (CPZ93_27235)	pilV	5627893..5628450 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
CPZ93_RS26605 (CPZ93_27240)	pilW	5628447..5629271 (+)	825	WP_003123396.1	type 4a pilus minor pilin PilW	-
CPZ93_RS26610 (CPZ93_27245)	pilX	5629268..5629855 (+)	588	WP_003112826.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=254563 CPZ93_RS26580 WP_003094694.1 5624169..5625506(+) (pilR) [Pseudomonas aeruginosa strain PA59]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=254563 CPZ93_RS26580 WP_003094694.1 5624169..5625506(+) (pilR) [Pseudomonas aeruginosa strain PA59]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATCGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384