Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   DK181_RS08070 Genome accession   NZ_CP029490
Coordinates   1668767..1669423 (+) Length   218 a.a.
NCBI ID   WP_002960006.1    Uniprot ID   A0ABM6W8A9
Organism   Streptococcus sobrinus strain SL1     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1663767..1674423
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK181_RS08040 (DK182_08040) - 1664707..1665456 (-) 750 WP_002962125.1 alpha/beta hydrolase family protein -
  DK181_RS08050 (DK182_08050) - 1666025..1666414 (-) 390 WP_002963223.1 rhodanese-like domain-containing protein -
  DK181_RS08055 (DK182_08055) - 1666606..1667571 (-) 966 WP_002960010.1 ROK family glucokinase -
  DK181_RS08060 (DK182_08060) - 1667564..1667785 (-) 222 WP_002960009.1 YqgQ family protein -
  DK181_RS08065 (DK182_08065) - 1668075..1668599 (-) 525 WP_002960008.1 Dps family protein -
  DK181_RS08070 (DK182_08070) cclA/cilC 1668767..1669423 (+) 657 WP_002960006.1 prepilin peptidase Machinery gene
  DK181_RS08075 (DK182_08075) - 1669445..1670287 (-) 843 WP_002960004.1 NAD(P)H-hydrate dehydratase -
  DK181_RS08080 (DK182_08080) - 1670284..1671141 (-) 858 WP_019768917.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  DK181_RS08085 (DK182_08085) - 1671277..1671633 (+) 357 WP_019770894.1 hypothetical protein -
  DK181_RS08090 (DK182_08090) - 1671667..1671825 (-) 159 WP_002963133.1 FeoB-associated Cys-rich membrane protein -
  DK181_RS08095 (DK182_08095) feoB 1671842..1673995 (-) 2154 WP_002963132.1 ferrous iron transport protein B -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23964.99 Da        Isoelectric Point: 4.6309

>NTDB_id=253765 DK181_RS08070 WP_002960006.1 1668767..1669423(+) (cclA/cilC) [Streptococcus sobrinus strain SL1]
MDTLLIFFLGASLGSFLGLVLDRFPEKSIIWPGSQCDNCGKALAIRDLIPILSEVANGFACRFCGEKLPVSYCLLELASG
LAFWLGWTGLLSWTQVFLILVSLLLSLYDLKGQNYPLVIILLAGLTLFLLEGGNTPVLVLLLLGILAQILPLGIGEGDLY
YLAFLALALDLYSLLWIIQLGSLLAILFIISRKEKRAVPFLPFLSLAYLLELVLLRMS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=253765 DK181_RS08070 WP_002960006.1 1668767..1669423(+) (cclA/cilC) [Streptococcus sobrinus strain SL1]
ATGGATACACTTTTAATATTCTTTCTTGGAGCCAGTCTGGGCTCCTTTCTGGGCTTGGTTCTGGACCGCTTTCCGGAAAA
ATCTATCATTTGGCCTGGCAGCCAGTGCGACAACTGTGGCAAGGCTCTGGCTATCAGAGATTTAATTCCCATCCTTTCTG
AAGTTGCTAATGGTTTTGCCTGCCGTTTCTGCGGAGAAAAATTACCAGTCAGCTATTGTCTGTTAGAACTGGCTTCTGGA
CTTGCTTTTTGGCTGGGCTGGACGGGGCTATTGAGTTGGACCCAGGTCTTTTTGATTTTGGTCAGCCTTCTGCTCAGCCT
CTACGACCTCAAGGGCCAAAATTATCCTCTAGTCATTATTTTGCTGGCGGGACTCACTTTGTTTTTGCTTGAGGGTGGCA
ATACTCCGGTCTTGGTTCTTCTTCTCTTGGGCATTCTGGCTCAAATCCTACCCTTAGGAATCGGAGAGGGGGACCTCTAT
TATTTGGCCTTTCTAGCTCTAGCTTTGGACCTTTATTCCCTGCTCTGGATAATTCAGTTGGGAAGCCTCTTGGCCATCCT
TTTTATCATCAGTCGCAAAGAAAAAAGAGCAGTTCCTTTCCTGCCCTTTCTGAGTTTAGCTTATTTGCTTGAATTGGTTT
TGCTGAGGATGAGCTGA

Domains

Predicted by InterProScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(9-85)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

45.894

94.954

0.436
  cclA/cilC Streptococcus pneumoniae TIGR4

45.411

94.954

0.431
  cclA/cilC Streptococcus pneumoniae Rx1

46.269

92.202

0.427
  cclA/cilC Streptococcus pneumoniae D39

46.269

92.202

0.427
  cclA/cilC Streptococcus pneumoniae R6

46.269

92.202

0.427
  cclA/cilC Streptococcus mitis NCTC 12261

42.381

96.33

0.408