Detailed information NTG0253725

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: DK181_RS03030
• Genome accession: NZ_CP029490
• Coordinates: 586513..588744 (+)
• Length: 743 a.a.
• NCBI ID: WP_019786964.1
• Uniprot ID: A0ABM6W4P2
• Organism: Streptococcus sobrinus strain SL1
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 581513..593744

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK181_RS03000 (DK182_03000)	-	581822..582244 (+)	423	WP_002962402.1	YtxH domain-containing protein	-
DK181_RS03005 (DK182_03005)	-	582443..583255 (+)	813	WP_019771382.1	DUF6612 family protein	-
DK181_RS03010 (DK182_03010)	-	583466..583765 (-)	300	WP_019770143.1	DUF3270 domain-containing protein	-
DK181_RS03015 (DK182_03015)	-	583967..584896 (+)	930	WP_002962408.1	peptidase U32 family protein	-
DK181_RS03020 (DK182_03020)	-	584906..585646 (+)	741	WP_002962409.1	lysophospholipid acyltransferase family protein	-
DK181_RS03025 (DK182_03025)	comEA/celA/cilE	585857..586516 (+)	660	WP_002962411.1	helix-hairpin-helix domain-containing protein	Machinery gene
DK181_RS03030 (DK182_03030)	comEC/celB	586513..588744 (+)	2232	WP_019786964.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
DK181_RS03035 (DK182_03035)	-	588887..589888 (+)	1002	WP_002962417.1	DUF805 domain-containing protein	-
DK181_RS03040 (DK182_03040)	-	589899..590510 (+)	612	WP_002962420.1	DUF805 domain-containing protein	-
DK181_RS03045 (DK182_03045)	-	590588..590983 (+)	396	WP_002962421.1	TM2 domain-containing protein	-
DK181_RS03050 (DK182_03050)	holA	591640..592686 (+)	1047	WP_002962422.1	DNA polymerase III subunit delta	-

Sequence

Protein

• Length: 743 a.a.
• Molecular weight: 84798.35 Da
• Isoelectric Point: 10.1145

>NTDB_id=253725 DK181_RS03030 WP_019786964.1 586513..588744(+) (comEC/celB) [Streptococcus sobrinus strain SL1]
MSKYFPIRPIYLAFLLVLLAYFIYSGYCLVGVLLAFTLCQLWRHYNLKKVGQVLLVLLSFGLAFWTYQYRVNQAYKSAPS
QVQELEMIPDTISTNGDQLSFRAKSQGRTYQVFYRLKSPEEKRFYQNVKDKLDLQVSAKLTQPQALRNFHGFNYRAYLKH
EGIYRLVTVDKIQGWIPAKRLTFFDRLHVLRRRALVTCQQKFPSPMNHYMTGLLFGYLDKDFDQMGDIYTSLGIIHLFAL
SGMQVDFFIGLYRKFLLRLGLRRDWVDILQVPFSVFYAGMTGYAPSVLRSLLQSFWGNLELKRLDNLAFSIFCMFLLRPN
FLLTTGGLLSFAYAFILAVLDFQNLSRVKAGLAQGASLSLGAFPLLAYLFGVFQPLSLVLTLAFSLVFDYLMLPFLTLAF
IVSPLIRLTWVNPLFSLLEQIVIWTHDIVGRPPVTGSPSLAILTLMLILLAFLHDYWQVKKIRPWLILLFVLLACLVKHP
LTNEVTMIDVGQGDSIFLRDSWGKTILIDTGGRVTFGQKEAWQKSNSDSNADKTVIPYLKSRGVGKIDQLVLTHTDTDHI
GDLEAVAKNFQIGQVLVSKGSLTRPAFVKRLKALKLKVRTVQVGDGLTIMGSRLHVLYPKSLGKGDNNDSLVLYGNLLNK
TFLFTGDQEKEGEEDLMKIYPNLHVQILKAGHHGSKGSSTPDFLKQISPEVALISAGQNNRYGHPNKETLERFKKQKMRV
YRTDQQGAISYRGFWDWHLETVR

Nucleotide

• Length: 2232 bp

>NTDB_id=253725 DK181_RS03030 WP_019786964.1 586513..588744(+) (comEC/celB) [Streptococcus sobrinus strain SL1]
ATGAGCAAATACTTTCCTATCAGGCCAATCTACTTGGCTTTTTTGCTGGTCTTGCTGGCTTATTTCATCTATTCAGGCTA
CTGCTTGGTCGGCGTCCTCTTGGCCTTCACTCTCTGTCAACTTTGGCGGCATTACAACTTAAAAAAAGTTGGCCAGGTTC
TGCTGGTTCTCTTGTCCTTTGGATTAGCCTTTTGGACCTATCAATATCGGGTCAATCAGGCTTATAAGTCTGCTCCCAGT
CAAGTACAGGAGCTGGAGATGATTCCAGATACTATCTCTACTAATGGTGACCAGCTCAGCTTTCGTGCTAAGAGTCAGGG
GCGGACTTATCAGGTTTTCTATCGCTTGAAATCACCTGAGGAAAAGCGATTCTATCAAAATGTAAAGGATAAACTTGACC
TGCAGGTTTCAGCCAAGCTAACTCAACCCCAGGCTCTGCGGAATTTTCATGGCTTTAACTATCGAGCCTATCTCAAGCAT
GAGGGTATTTATCGACTGGTGACTGTCGATAAAATTCAAGGCTGGATACCGGCCAAGCGACTGACCTTCTTTGACCGTCT
GCATGTCCTGAGACGGCGGGCTCTAGTAACTTGTCAACAGAAGTTTCCCAGTCCCATGAACCACTACATGACGGGGCTTC
TCTTTGGTTATCTGGATAAGGATTTTGACCAGATGGGCGATATTTATACCAGTCTGGGGATTATCCACCTTTTTGCCTTG
TCTGGTATGCAGGTTGATTTCTTTATCGGCCTTTATCGAAAATTCCTCTTACGACTTGGCCTGAGAAGGGATTGGGTGGA
TATTTTACAAGTGCCTTTTTCAGTTTTCTATGCTGGGATGACCGGTTATGCTCCCTCGGTTCTAAGAAGCCTGCTTCAGT
CTTTCTGGGGCAATCTGGAACTAAAGCGATTGGATAATCTGGCCTTTAGCATCTTTTGTATGTTTTTGCTGAGACCCAAC
TTCCTGCTGACCACTGGAGGCCTGCTTAGTTTTGCCTATGCCTTTATTTTGGCGGTGCTTGATTTCCAAAACTTGAGCAG
GGTTAAGGCAGGCCTAGCCCAGGGTGCCAGTTTGTCTTTGGGTGCCTTCCCTCTGCTGGCCTATTTATTTGGCGTTTTTC
AGCCTCTATCGCTTGTCTTGACCCTGGCCTTTTCCCTAGTTTTCGATTATCTGATGCTCCCCTTTTTGACTTTGGCCTTC
ATAGTCAGCCCGCTAATTAGACTGACCTGGGTCAATCCTCTCTTCAGCCTGCTGGAGCAAATTGTCATCTGGACTCATGA
TATTGTTGGCCGGCCTCCCGTTACTGGTAGTCCAAGTTTGGCTATTCTTACTCTCATGCTAATCTTATTAGCCTTTCTCC
ATGATTATTGGCAGGTCAAAAAGATTCGTCCTTGGCTAATTCTGCTCTTCGTTTTACTAGCCTGTTTGGTCAAACATCCT
TTGACCAATGAGGTGACCATGATTGATGTCGGTCAAGGAGATAGTATTTTCCTGCGCGATAGCTGGGGCAAGACTATTCT
AATTGATACTGGTGGACGGGTAACTTTTGGGCAGAAGGAGGCCTGGCAAAAGAGCAATTCAGATAGCAATGCGGACAAGA
CCGTCATTCCCTACCTTAAAAGTCGGGGTGTGGGGAAAATTGACCAGCTGGTTCTGACCCATACCGATACAGACCATATT
GGCGATTTGGAAGCTGTTGCCAAGAATTTTCAAATTGGCCAGGTACTGGTCAGCAAGGGTAGTCTGACAAGACCAGCTTT
TGTCAAGCGTCTCAAGGCTCTGAAGCTGAAGGTGAGGACAGTTCAAGTAGGCGATGGTTTAACAATTATGGGTAGTAGGC
TTCATGTCCTCTATCCCAAGAGTCTGGGCAAAGGTGACAATAATGATTCCTTAGTTCTCTATGGGAATCTGCTCAATAAG
ACTTTTCTCTTTACTGGCGATCAAGAAAAAGAAGGAGAGGAAGATCTGATGAAAATCTATCCCAATCTCCATGTCCAGAT
TCTCAAAGCCGGTCACCATGGTTCCAAAGGTTCGTCTACCCCAGATTTTCTCAAGCAAATCAGCCCAGAAGTCGCCCTTA
TTTCGGCGGGTCAAAATAATCGCTATGGTCACCCCAACAAGGAGACATTGGAGCGATTTAAGAAACAGAAAATGAGAGTT
TACCGGACTGATCAACAAGGGGCAATTTCTTATCGTGGCTTCTGGGATTGGCACCTAGAAACGGTTCGGTAA

Domains

Predicted by InterProScan.

• Domain of unknown function (DUF4131) (DUF4131) (25-173)

• Metallo-beta-lactamase superfamily (Lactamase_B) (489-697)

• Competence protein (Competence) (213-459)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	47.376	100	0.474
comEC/celB	Streptococcus mitis NCTC 12261	47.233	99.731	0.471
comEC/celB	Streptococcus pneumoniae TIGR4	46.765	99.865	0.467
comEC/celB	Streptococcus pneumoniae R6	46.496	99.865	0.464
comEC/celB	Streptococcus pneumoniae Rx1	46.496	99.865	0.464
comEC/celB	Streptococcus pneumoniae D39	46.496	99.865	0.464
comEC	Lactococcus lactis subsp. cremoris KW2	46.237	100	0.463