Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   CR542_RS08525 Genome accession   NZ_CP024126
Coordinates   1665298..1665942 (+) Length   214 a.a.
NCBI ID   WP_004194621.1    Uniprot ID   A0A126UP31
Organism   Streptococcus suis strain HA0609     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1660298..1670942
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CR542_RS08505 (CR542_08490) pflA 1661436..1662227 (-) 792 WP_012027587.1 pyruvate formate-lyase-activating protein -
  CR542_RS08510 (CR542_08495) - 1662348..1663685 (-) 1338 WP_099425945.1 hemolysin family protein -
  CR542_RS08515 (CR542_08500) - 1663818..1664597 (+) 780 WP_004194629.1 ABC transporter ATP-binding protein -
  CR542_RS08520 (CR542_08505) - 1664613..1665167 (-) 555 WP_004194627.1 tRNA (mnm(5)s(2)U34)-methyltransferase -
  CR542_RS08525 (CR542_08510) cclA/cilC 1665298..1665942 (+) 645 WP_004194621.1 prepilin peptidase Machinery gene
  CR542_RS08530 (CR542_08515) - 1666050..1667510 (+) 1461 WP_004194619.1 nicotinate phosphoribosyltransferase -
  CR542_RS08535 (CR542_08520) nadE 1667523..1668347 (+) 825 WP_004194617.1 ammonia-dependent NAD(+) synthetase -
  CR542_RS08540 (CR542_08525) - 1669221..1669748 (-) 528 WP_004194600.1 VanZ family protein -
  CR542_RS08545 (CR542_08530) rlmN 1669745..1670857 (-) 1113 WP_004194597.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24227.39 Da        Isoelectric Point: 8.4760

>NTDB_id=252400 CR542_RS08525 WP_004194621.1 1665298..1665942(+) (cclA/cilC) [Streptococcus suis strain HA0609]
MKTIILFFLGASIGSFLGLVIDRFPEQSIIAPSSHCNACKRRLKAWDLIPVLSQLSTKSKCRYCKAKIPYWYLGLEFLAG
LVVLLCHFQVLNLTETILILAGLVLTIYDIKHQEYPFAVWLIFTFIALILSQLNWLFCGFLLLAYLTEKWQINIGSGDFL
YLASLALICGFTELLWIIQISSLLGLLVFAIFKPKSIPYVPLLFLSSIPIILCI

Nucleotide


Download         Length: 645 bp        

>NTDB_id=252400 CR542_RS08525 WP_004194621.1 1665298..1665942(+) (cclA/cilC) [Streptococcus suis strain HA0609]
ATGAAGACAATTATCCTATTTTTCCTTGGAGCTTCTATCGGCTCCTTCTTGGGATTGGTCATCGACCGTTTCCCTGAACA
GTCCATTATCGCCCCCTCTAGTCACTGCAATGCCTGCAAACGACGGCTCAAGGCATGGGACTTAATTCCAGTCCTATCCC
AGCTTTCGACAAAATCCAAATGCCGTTACTGCAAGGCGAAGATACCTTATTGGTATCTGGGACTAGAATTCTTAGCTGGT
CTAGTTGTCCTGCTCTGCCATTTTCAAGTCCTAAACCTAACCGAAACCATTCTCATCTTGGCAGGACTAGTTTTGACCAT
TTACGACATCAAACATCAGGAATATCCTTTTGCTGTCTGGCTCATTTTTACTTTTATTGCTCTGATACTCTCCCAGCTCA
ACTGGCTCTTCTGTGGCTTTTTACTCTTGGCCTATCTGACTGAAAAATGGCAAATCAATATTGGTTCTGGTGACTTTCTC
TATCTGGCAAGTTTGGCCTTAATATGTGGATTTACAGAACTCCTCTGGATTATCCAGATTAGTTCCCTCCTAGGGCTTCT
TGTCTTCGCCATTTTCAAACCCAAGTCTATTCCCTACGTACCACTCCTTTTTCTTTCAAGTATTCCTATCATTCTGTGCA
TCTAA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(9-88)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A126UP31

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

49.528

99.065

0.491
  cclA/cilC Streptococcus pneumoniae Rx1

49.029

96.262

0.472
  cclA/cilC Streptococcus pneumoniae D39

49.029

96.262

0.472
  cclA/cilC Streptococcus pneumoniae R6

49.029

96.262

0.472
  cclA/cilC Streptococcus pneumoniae TIGR4

48.058

96.262

0.463
  cclA/cilC Streptococcus mitis NCTC 12261

45.755

99.065

0.453

Multiple sequence alignment