Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SAB_RS09525 Genome accession   NC_007622
Coordinates   1908056..1908679 (-) Length   207 a.a.
NCBI ID   WP_001045137.1    Uniprot ID   -
Organism   Staphylococcus aureus RF122     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1903056..1913679
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAB_RS09500 (SAB1777c) - 1903240..1904436 (-) 1197 WP_000238227.1 metallophosphoesterase family protein -
  SAB_RS09510 (SAB1778c) - 1905520..1905864 (-) 345 WP_000290301.1 YlbF/YmcA family competence regulator -
  SAB_RS09515 (SAB1779c) - 1905933..1907057 (-) 1125 WP_000992510.1 DUF445 domain-containing protein -
  SAB_RS09520 (SAB1780c) - 1907236..1907700 (-) 465 WP_000375864.1 XRE family transcriptional regulator XdrA -
  SAB_RS09525 (SAB1781c) vraR 1908056..1908679 (-) 624 WP_001045137.1 response regulator Regulator
  SAB_RS09530 (SAB1782c) - 1908701..1909813 (-) 1113 WP_000437974.1 GAF domain-containing sensor histidine kinase -
  SAB_RS09535 (SAB1783) - 1909976..1910797 (+) 822 WP_000669372.1 RluA family pseudouridine synthase -
  SAB_RS09540 (SAB1784c) fumC 1911248..1912633 (-) 1386 WP_000116236.1 class II fumarate hydratase -
  SAB_RS09545 (SAB1785c) - 1912829..1913224 (-) 396 WP_000901023.1 hypothetical protein -

Sequence

Protein


Download         Length: 207 a.a.        Molecular weight: 23865.58 Da        Isoelectric Point: 5.8099

>NTDB_id=25235 SAB_RS09525 WP_001045137.1 1908056..1908679(-) (vraR) [Staphylococcus aureus RF122]
MNKVILVDDHYIVRQGLRFLLSTIENIEVLQDFADGETFLEYLKEHEHPDIVLLDLVMPGMNGIEITVYIKAHYPDIKVL
VLTSYVDDEHVISAINKGADGYEMKDVEPQQLIETIRRVMNGEKMIHPKAQDVFETVSQKPHYTNKLSKREIEVLREMVK
GKTNKEIAETLFVSEKTIKTHVSHIFSKLQVSDRTQAAIYAMENKLI

Nucleotide


Download         Length: 624 bp        

>NTDB_id=25235 SAB_RS09525 WP_001045137.1 1908056..1908679(-) (vraR) [Staphylococcus aureus RF122]
ATGAACAAAGTAATATTAGTAGATGACCATTATATTGTGCGACAAGGATTGCGATTTTTATTATCCACGATTGAAAACAT
AGAAGTTTTACAAGACTTTGCAGATGGAGAAACATTTTTAGAATATTTAAAAGAGCATGAGCACCCTGATATTGTGCTAT
TAGATTTAGTGATGCCTGGCATGAATGGTATTGAAATTACGGTATATATTAAGGCACATTATCCGGATATTAAAGTTTTG
GTATTAACAAGTTATGTTGATGATGAACATGTAATTTCAGCAATCAATAAAGGTGCTGATGGTTATGAAATGAAAGACGT
TGAGCCTCAGCAATTAATTGAAACTATTAGACGAGTTATGAACGGTGAAAAAATGATACATCCTAAGGCACAAGATGTAT
TCGAAACAGTTAGCCAAAAACCACACTACACGAATAAGTTGTCAAAGAGAGAAATTGAAGTGTTACGTGAAATGGTTAAA
GGTAAAACAAATAAAGAGATAGCAGAAACTTTATTTGTATCTGAAAAAACAATTAAAACACATGTCAGTCATATATTTAG
TAAATTACAAGTTAGCGATCGTACACAAGCAGCAATTTATGCAATGGAAAATAAGTTGATTTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(146-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.58

100

0.406
  degU Bacillus subtilis subsp. subtilis str. 168

35.135

100

0.377
  letA Legionella pneumophila str. Paris

35.714

100

0.362
  letA Legionella pneumophila strain ERS1305867

35.714

100

0.362