Detailed information NTG0252108

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: DEH83_RS04905
• Genome accession: NZ_CP029207
• Coordinates: 967664..970222 (+)
• Length: 852 a.a.
• NCBI ID: WP_255777213.1
• Uniprot ID: -
• Organism: Streptococcus constellatus strain TCV107
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 962664..975222

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DEH83_RS04885 (DEH83_04880)	-	964177..964686 (+)	510	WP_003071518.1	hypothetical protein	-
DEH83_RS04890 (DEH83_04885)	nrdI	964762..965217 (+)	456	WP_150202533.1	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	-
DEH83_RS04895 (DEH83_04890)	argS	965269..966957 (-)	1689	WP_255777211.1	arginine--tRNA ligase	-
DEH83_RS04900 (DEH83_04895)	argR	967061..967501 (+)	441	WP_255777212.1	arginine repressor	-
DEH83_RS04905 (DEH83_04900)	hexA	967664..970222 (+)	2559	WP_255777213.1	DNA mismatch repair protein MutS	Machinery gene
DEH83_RS04910 (DEH83_04905)	-	970363..970821 (-)	459	WP_255777214.1	DUF3021 domain-containing protein	-
DEH83_RS04915 (DEH83_04910)	brsR	970818..971258 (-)	441	WP_037598388.1	LytTR family DNA-binding domain-containing protein	Regulator
DEH83_RS04920 (DEH83_04915)	hexB	971505..973451 (+)	1947	WP_006269779.1	DNA mismatch repair endonuclease MutL	Machinery gene
DEH83_RS04925 (DEH83_04920)	-	973780..974289 (-)	510	WP_003071502.1	helix-turn-helix domain-containing protein	-
DEH83_RS04930 (DEH83_04925)	ruvA	974451..975041 (+)	591	WP_255777231.1	Holliday junction branch migration protein RuvA	Machinery gene

Sequence

Protein

• Length: 852 a.a.
• Molecular weight: 95978.38 Da
• Isoelectric Point: 4.9598

>NTDB_id=252108 DEH83_RS04905 WP_255777213.1 967664..970222(+) (hexA) [Streptococcus constellatus strain TCV107]
MTKEKLSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAINAAQILEIALTSRNKNSENPIPMAGVPYHSVQQYIDVLI
ESGYKVAIAEQVEDPKKAVGVVKREVVQVITPGTVVDSSKPDSQNNFLVALDKLENLYGLAYMDLVTGEFQVTSLSDFNI
VCGEIRNLRAREVVLGYELPESEHQVLANQMNLLLSQVGTAFEDVQLLGDELSRLEHQVAGKLLEYVHQTQLRELSHLKR
VHHYEIKDFLQMDYATMASLDLTENARTGKKHGSLYWLMDETKTAMGTRLLRRWIQQPLIDKERILKRQDVVQVFLDYFF
ERSDLADSLKGVYDIERLASRVSFGKTNPKDLLQLAATLSNVPQIKGILQGIDHPVLGQLIENLDDIPELANLIQSAISP
DAPNVITEGNIIQTGFDETLDKYRVVLRDGTSWIADIEAKERAASGINNLKIDYNKKDGYYFHVTNSQLEHVPSHFFRKA
TLKNSERFGTEELARIEGEMLEAREKSANLEYEIFMRIREEAGKYIKRLQSLAQTLATIDVLQSFAAVAEKQRFVRPEFI
ERPSIEIDKGRHAVVEKVMGAQTYIPNSISMDENVNVQLITGPNMSGKSTYMRQLAIIVIMAQMGSYVSAESAQLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANHAISQATEHSLILFDELGRGTATYDGMALAQAIIEYIHNRTGAKTLFATHYHEL
TDLSTSLTQLENVHVATLEKDGQVTFLHKIEAGPADKSYGIHVAKIAGLPNDLLMRADQILTRLEEQANEKPSLNPSNKG
ANDSKENQVSEQISLFTETTESPILEKLRQLDIYNMTPMEVMLAVSDMKKHL

Nucleotide

• Length: 2559 bp

>NTDB_id=252108 DEH83_RS04905 WP_255777213.1 967664..970222(+) (hexA) [Streptococcus constellatus strain TCV107]
ATGACAAAAGAAAAACTATCTCCGGGAATGCAACAGTATTTAGATATAAAAAAAGATTATCCGGATGCTTTTTTGCTATT
TCGTATGGGAGATTTTTATGAATTATTCTATGAAGATGCGATCAATGCAGCACAGATTTTAGAAATTGCTCTGACTAGCC
GTAATAAAAATTCGGAAAATCCAATCCCGATGGCAGGAGTTCCCTACCATTCGGTGCAACAGTATATTGATGTTTTAATT
GAATCGGGCTATAAAGTAGCGATTGCAGAGCAGGTGGAAGATCCTAAAAAAGCAGTTGGTGTAGTCAAACGTGAGGTGGT
ACAAGTCATCACACCGGGGACAGTCGTTGATTCTTCAAAACCAGATAGTCAAAATAATTTCTTGGTAGCTTTAGATAAAC
TAGAAAATTTATATGGGCTGGCTTACATGGACTTGGTTACAGGTGAATTTCAGGTCACAAGTCTCAGTGACTTTAACATA
GTCTGTGGAGAAATTCGGAACCTGCGAGCGCGTGAAGTGGTCTTAGGATATGAATTACCTGAATCAGAGCACCAAGTGTT
GGCAAATCAAATGAATTTGTTATTATCACAGGTGGGAACTGCTTTTGAAGATGTTCAGCTATTAGGGGATGAATTGTCTC
GCTTAGAACATCAAGTAGCTGGGAAACTGTTAGAATATGTTCATCAGACGCAGCTGCGTGAGCTTAGTCACTTAAAGCGA
GTTCATCATTATGAAATCAAGGATTTCTTACAGATGGATTATGCAACCATGGCAAGTCTGGATTTAACAGAGAATGCACG
TACAGGAAAGAAGCACGGTAGTCTGTATTGGCTGATGGATGAGACCAAGACAGCTATGGGAACGCGACTTTTAAGAAGAT
GGATTCAGCAGCCCTTGATTGACAAAGAGCGAATCCTTAAGCGGCAGGATGTCGTGCAGGTATTTCTAGATTATTTTTTT
GAGCGCAGTGATTTAGCAGATAGTCTCAAAGGTGTGTATGACATTGAGCGTTTAGCCAGTCGTGTTTCGTTTGGAAAGAC
CAATCCGAAAGATTTATTGCAGTTGGCGGCAACATTGAGCAATGTCCCTCAGATTAAGGGAATTTTACAAGGAATTGATC
ATCCTGTTTTGGGACAGTTGATTGAAAACTTGGATGACATTCCAGAATTGGCAAACTTGATTCAGTCGGCAATTTCTCCC
GATGCTCCAAATGTTATTACTGAAGGGAATATCATTCAAACTGGTTTTGATGAAACCTTAGATAAGTATCGAGTGGTTCT
GCGAGATGGTACGAGCTGGATTGCTGATATCGAAGCGAAAGAAAGGGCGGCTAGTGGGATTAATAATCTAAAAATTGATT
ACAATAAAAAAGATGGTTATTATTTCCATGTCACTAATTCACAGTTGGAGCACGTACCTAGCCATTTTTTCCGAAAAGCA
ACGTTGAAAAATTCAGAACGATTTGGTACAGAGGAATTGGCTCGTATTGAAGGCGAAATGTTGGAAGCGCGTGAAAAATC
TGCTAATTTAGAATATGAGATTTTTATGCGTATTCGTGAAGAAGCTGGCAAATATATCAAGCGTCTGCAATCCTTGGCAC
AAACTCTGGCAACGATTGATGTATTACAAAGTTTTGCAGCAGTTGCTGAAAAGCAACGCTTTGTACGCCCAGAATTTATT
GAACGTCCTTCCATTGAAATTGATAAGGGACGGCATGCAGTTGTAGAAAAAGTCATGGGTGCACAAACCTATATTCCTAA
CAGCATTTCAATGGATGAAAATGTCAACGTTCAGCTAATTACAGGTCCAAATATGAGTGGGAAGTCAACCTATATGCGTC
AATTAGCGATTATTGTTATTATGGCTCAAATGGGTTCCTATGTTTCAGCTGAGAGTGCTCAATTACCAATTTTTGATGCC
ATCTTCACTCGAATTGGTGCGGCAGATGACTTGGTATCTGGACAATCAACCTTTATGGTAGAAATGATGGAAGCAAATCA
TGCTATTTCTCAAGCAACAGAGCACTCTCTTATTCTTTTTGATGAGTTGGGAAGAGGGACAGCGACATATGATGGGATGG
CTCTTGCTCAGGCGATTATTGAATATATCCACAATCGAACAGGGGCAAAGACCCTTTTTGCCACACACTATCATGAGTTG
ACAGACTTGTCAACTAGCTTGACACAGTTAGAAAATGTTCATGTAGCAACTTTAGAAAAAGATGGGCAAGTGACCTTCCT
TCATAAGATTGAAGCTGGTCCTGCGGATAAATCTTATGGGATTCATGTGGCAAAAATTGCAGGTTTACCGAATGATTTGC
TGATGAGAGCAGACCAGATCTTAACACGATTAGAAGAACAAGCAAATGAGAAACCGTCTCTCAATCCTTCTAATAAAGGA
GCTAATGATAGTAAGGAAAATCAAGTATCTGAGCAGATATCTTTATTCACAGAAACAACTGAATCCCCTATTTTAGAAAA
ATTACGCCAGTTGGACATCTACAACATGACTCCAATGGAAGTGATGCTGGCTGTATCAGATATGAAAAAACATCTCTGA

Domains

Predicted by InterProScan.

• MutS domain I (MutS_I) (8-118)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain V (MutS_V) (599-785)

• MutS domain III (MutS_III) (255-546)

• MutS domain II (MutS_II) (126-239)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	76.174	100	0.762
mutS	Pseudomonas stutzeri strain ATCC 17587	36.806	100	0.373