Detailed information NTG0251676

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: C3363_RS01915
• Genome accession: NZ_CP029150
• Coordinates: 390578..391252 (-)
• Length: 224 a.a.
• NCBI ID: WP_010787261.1
• Uniprot ID: B8F851
• Organism: Glaesserella parasuis strain GZ20170512
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 385578..396252

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C3363_RS01885 (C3363_01910)	lolB	386052..386684 (+)	633	WP_159179811.1	lipoprotein insertase outer membrane protein LolB	-
C3363_RS01890 (C3363_01915)	ispE	386686..387531 (+)	846	WP_015940038.1	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase	-
C3363_RS01895 (C3363_01920)	-	387559..388509 (+)	951	WP_005713153.1	ribose-phosphate pyrophosphokinase	-
C3363_RS01900 (C3363_01925)	pyrD	388756..389763 (+)	1008	WP_010787260.1	quinone-dependent dihydroorotate dehydrogenase	-
C3363_RS01905 (C3363_01930)	-	389884..390135 (-)	252	WP_005713159.1	hypothetical protein	-
C3363_RS01910 (C3363_01935)	-	390132..390323 (-)	192	WP_015940041.1	hypothetical protein	-
C3363_RS01915 (C3363_01940)	crp	390578..391252 (-)	675	WP_010787261.1	cAMP-activated global transcriptional regulator CRP	Regulator
C3363_RS01920 (C3363_01945)	-	391319..391543 (-)	225	WP_005713165.1	YheU family protein	-
C3363_RS01925 (C3363_01950)	slmA	391551..392156 (-)	606	WP_005713169.1	nucleoid occlusion factor SlmA	-
C3363_RS01930 (C3363_01955)	dut	392165..392620 (-)	456	WP_005713171.1	dUTP diphosphatase	-
C3363_RS01935 (C3363_01960)	-	392646..392972 (-)	327	WP_005713172.1	hypothetical protein	-
C3363_RS01940 (C3363_01965)	coaBC	392982..394184 (-)	1203	WP_010787262.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
C3363_RS01945 (C3363_01970)	radC	394354..395070 (+)	717	WP_010787263.1	RadC family protein	Machinery gene
C3363_RS01950 (C3363_01975)	rpmB	395196..395432 (+)	237	WP_005713177.1	50S ribosomal protein L28	-
C3363_RS01955 (C3363_01980)	rpmG	395444..395614 (+)	171	WP_005624479.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25208.17 Da
• Isoelectric Point: 6.9079

>NTDB_id=251676 C3363_RS01915 WP_010787261.1 390578..391252(-) (crp) [Glaesserella parasuis strain GZ20170512]
MQDVSISTAQLEDVSPLPSIHDPSVEWFLTHCHIHRYPAKYTLIHAGEDAESLFYIVSGAVSVFIKDEEGKEMLLTNLGQ
GEFVGEISLFEEKAQPRTAWVRTKGNCEIAEISYKKFKQLVHLNPDILMYLSAQMARRLRMTSRQVSNLAFLDVTGRIAQ
TLMNLAKMPDAMTHPQGMQIKITRQEIGQMVGCSRETVGRILKMLEDEGLISAHGKTIVVYGTR

Nucleotide

• Length: 675 bp

>NTDB_id=251676 C3363_RS01915 WP_010787261.1 390578..391252(-) (crp) [Glaesserella parasuis strain GZ20170512]
ATGCAAGATGTTTCAATCTCAACCGCACAGCTTGAAGATGTCAGCCCATTACCATCCATTCACGATCCTTCGGTGGAATG
GTTTTTAACTCACTGTCATATTCATCGTTATCCAGCAAAATATACTTTAATTCACGCAGGTGAAGATGCTGAATCACTGT
TTTATATTGTCAGCGGAGCTGTGTCTGTCTTTATCAAGGATGAAGAAGGCAAGGAGATGTTATTAACCAATTTAGGACAA
GGCGAATTTGTCGGTGAAATCAGCCTTTTTGAAGAAAAGGCTCAGCCTCGCACTGCTTGGGTAAGAACCAAAGGCAACTG
TGAAATTGCTGAAATTTCTTATAAAAAATTCAAGCAATTAGTTCATCTAAATCCTGATATCTTAATGTATCTCTCAGCTC
AGATGGCTCGCCGTTTACGAATGACATCAAGACAGGTTAGTAACCTTGCATTCCTTGATGTAACAGGTCGTATTGCTCAA
ACATTGATGAATTTAGCTAAAATGCCTGATGCGATGACTCACCCTCAGGGTATGCAGATTAAAATTACTCGCCAAGAAAT
TGGTCAAATGGTTGGTTGCTCACGAGAAACTGTAGGCCGTATTTTGAAAATGCTTGAGGATGAAGGGTTAATCTCTGCAC
ATGGTAAAACTATCGTTGTGTATGGGACAAGATAA

Domains

Predicted by InterProScan.

• Cyclic nucleotide-binding domain (cNMP_binding) (35-121)

• Crp-like helix-turn-helix domain (HTH_Crp_2) (156-220)

3D structure

• AlphaFold DB: B8F851

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Vibrio cholerae strain A1552	75.862	90.625	0.687
crp	Haemophilus influenzae Rd KW20	73.399	90.625	0.665
crp	Acinetobacter baumannii D1279779	48.5	89.286	0.433