Detailed information NTG0249115

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: CP942_RS14740
• Genome accession: NZ_CP023666
• Coordinates: 3003600..3004757 (+)
• Length: 385 a.a.
• NCBI ID: WP_020453119.1
• Uniprot ID: A0A6I7TVP7
• Organism: Bacillus paralicheniformis strain Bac48
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2998600..3009757

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CP942_RS14715	tuaH	2998721..2999908 (+)	1188	WP_026580178.1	teichuronic acid biosynthesis protein TuaH	-
CP942_RS14720	-	3000039..3001103 (+)	1065	WP_095292064.1	glycosyltransferase family 4 protein	-
CP942_RS14725	-	3001212..3001568 (+)	357	Protein_2855	hypothetical protein	-
CP942_RS14730	-	3001646..3002724 (-)	1079	Protein_2856	LCP family protein	-
CP942_RS14735	-	3002739..3003377 (-)	639	WP_105979660.1	YigZ family protein	-
CP942_RS14740	degS	3003600..3004757 (+)	1158	WP_020453119.1	sensor histidine kinase	Regulator
CP942_RS14745	degU	3004839..3005528 (+)	690	WP_003185730.1	two-component system response regulator DegU	Regulator
CP942_RS14750	-	3005648..3006490 (+)	843	WP_020453118.1	DegV family protein	-
CP942_RS14755	comFA	3006614..3008008 (+)	1395	WP_105980589.1	DEAD/DEAH box helicase	Machinery gene
CP942_RS14760	-	3008063..3008347 (+)	285	WP_020453116.1	late competence development ComFB family protein	-
CP942_RS14765	comFC	3008304..3009041 (+)	738	WP_105979662.1	double zinc ribbon domain-containing protein	Machinery gene
CP942_RS14770	-	3009100..3009519 (+)	420	WP_020453114.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44650.34 Da
• Isoelectric Point: 6.7862

>NTDB_id=249115 CP942_RS14740 WP_020453119.1 3003600..3004757(+) (degS) [Bacillus paralicheniformis strain Bac48]
MSVSKMDSKVLDSIIMKMLKTVDGSKDEVFQIGEQSRQQYEGLVEELKQIKQQVNEVIDLGDRLEVHARHARNRLSEVSR
NFHKFSEEEIREAYEKAHKLQVELTMIQQREKQLREKRDDLERRLLGLQEIIERSEGLVSQITVVLNYLNQDLRQVGVLL
EDAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDKGTEEGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLNTIEDYHGKAKIHFQCIGESEDRRIAPRFEVALFRLAQEAVTNALKHSESTEIHVKVEV
TKDFVTLIIKDNGNGFDLKEVKGKKNKSFGLLGMKERVDLLEGSMTIDSKIGLGTFILIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=249115 CP942_RS14740 WP_020453119.1 3003600..3004757(+) (degS) [Bacillus paralicheniformis strain Bac48]
GTGAGTGTTTCCAAAATGGACTCCAAAGTTTTAGATTCAATCATTATGAAGATGTTAAAAACGGTTGACGGGAGCAAGGA
TGAGGTCTTTCAAATCGGAGAGCAGTCCCGTCAGCAATATGAAGGCTTGGTAGAAGAGCTGAAGCAGATTAAACAGCAGG
TCAACGAAGTCATCGATCTTGGAGACAGGCTGGAAGTGCATGCCCGCCATGCGCGAAACCGCTTGTCTGAGGTCAGCAGA
AACTTTCATAAATTCAGTGAAGAAGAGATTCGCGAAGCTTATGAAAAAGCCCACAAACTGCAGGTTGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGAGAGAGAAGCGTGATGATCTGGAACGGCGCCTTTTGGGGCTTCAGGAAATCATCGAGC
GTTCAGAAGGGCTTGTCAGCCAGATTACCGTCGTCTTAAACTATTTAAATCAGGATCTGCGCCAGGTTGGCGTTCTCCTA
GAAGATGCGCAGGCCAAACAGGATTTCGGACTGCGGATCATCGAAGCCCAAGAGGAAGAAAGAAAAAGGGTCTCAAGGGA
AATCCACGACGGCCCTGCGCAAATGCTGGCCAACGTCATGATGAGATCTGAGCTGATCGAACGCATCTTCAGAGACAAAG
GAACAGAAGAAGGCTTTCAGGAAATTAGAAACCTCCGGCAAAACGTCAGAAATGCTCTTTATGAAGTCAGAAGAATCATT
TATGATTTAAGACCGATGGCTTTAGACGATTTGGGATTGATACCGACGCTCAGAAAATACTTGAACACGATCGAAGATTA
TCATGGAAAAGCAAAGATCCATTTCCAATGCATCGGAGAATCCGAAGATAGAAGAATAGCACCGCGGTTTGAGGTTGCAC
TTTTCCGGCTTGCACAGGAAGCAGTGACAAACGCCTTAAAACACTCCGAATCAACTGAGATTCATGTTAAAGTAGAAGTG
ACAAAAGATTTTGTGACGTTGATTATCAAAGACAATGGAAACGGCTTTGACTTAAAAGAAGTTAAAGGCAAGAAGAACAA
ATCTTTCGGTCTGCTAGGTATGAAAGAAAGAGTCGACTTGCTCGAAGGTTCAATGACAATCGATTCGAAAATAGGTCTTG
GGACATTTATTTTGATTAAAGTTCCGCTGTCTTTGTAA

Domains

Predicted by InterproScan.

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (292-384)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A0A6I7TVP7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	89.351	100	0.894