Detailed information NTG0248588

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: DB248_RS06350
• Genome accession: NZ_CP028841
• Coordinates: 1192699..1193661 (-)
• Length: 320 a.a.
• NCBI ID: WP_010922426.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain CCUG 4207
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1187699..1198661

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DB248_RS06335 (DB248_06340)	-	1188536..1189243 (-)	708	WP_002989211.1	O-methyltransferase	-
DB248_RS06340 (DB248_06345)	-	1189309..1190505 (-)	1197	WP_002995765.1	OFA family MFS transporter	-
DB248_RS06345 (DB248_06350)	pepF	1190881..1192686 (-)	1806	WP_010922425.1	oligoendopeptidase F	Regulator
DB248_RS06350 (DB248_06355)	coiA	1192699..1193661 (-)	963	WP_010922426.1	competence protein CoiA	Machinery gene
DB248_RS06355 (DB248_06360)	-	1193956..1194672 (-)	717	WP_002995774.1	pseudouridine synthase	-
DB248_RS06360 (DB248_06365)	nagB	1194791..1195495 (-)	705	WP_010922428.1	glucosamine-6-phosphate deaminase	-
DB248_RS06365 (DB248_06370)	queA	1195697..1196725 (+)	1029	WP_010922429.1	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	-
DB248_RS06370 (DB248_06375)	-	1196732..1197952 (+)	1221	WP_010922430.1	DUF3114 domain-containing protein	-
DB248_RS06375 (DB248_06380)	-	1198066..1198656 (-)	591	WP_010922431.1	serine hydrolase	-

Sequence

Protein

• Length: 320 a.a.
• Molecular weight: 37859.28 Da
• Isoelectric Point: 10.2431

>NTDB_id=248588 DB248_RS06350 WP_010922426.1 1192699..1193661(-) (coiA) [Streptococcus pyogenes strain CCUG 4207]
MTKILTALDDKNQLISLVTQPISTKPPFRCPACKSPVRLRQGTIRRPHFAHVQLAHCQFQAENESEEHLTLKAKLYTSLV
RTEAVCIEKYLPELQQIADLWVNDKLALEIQCSPLPVERLKKRTKAYQEKGYPVRWLLGRKLWLNTHLTALQKQFLYFSS
SLGFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLDHNIMEMFRLPYQQEILYSYQKKMTVNLSKRIQRALLARHP
KWLRRQEKAYLSGYNLLMLTTDAFYPQWRPVQSSSGFCQIKGNLRPYYESFKVYYKKEKDKKVQTLFSPKYYVKMDSNRK

Nucleotide

• Length: 963 bp

>NTDB_id=248588 DB248_RS06350 WP_010922426.1 1192699..1193661(-) (coiA) [Streptococcus pyogenes strain CCUG 4207]
GTGACAAAAATATTAACCGCTTTAGATGATAAGAATCAGCTCATTTCGCTAGTAACTCAGCCTATTTCAACGAAACCGCC
TTTTCGTTGCCCAGCTTGCAAATCTCCTGTTCGCTTGCGTCAGGGGACAATTAGACGACCTCATTTTGCCCATGTACAAC
TAGCTCATTGTCAATTCCAAGCAGAAAATGAATCTGAGGAACATTTGACGTTGAAGGCAAAACTTTACACCAGTTTAGTC
CGAACAGAAGCTGTCTGTATTGAAAAATATCTTCCTGAGCTGCAACAGATAGCAGACCTTTGGGTGAATGATAAGTTAGC
CTTAGAAATTCAGTGCAGTCCCTTGCCAGTTGAGCGTCTAAAGAAACGCACCAAAGCCTATCAAGAAAAGGGGTATCCGG
TACGATGGTTACTGGGAAGAAAATTGTGGCTTAACACTCACTTAACTGCTTTGCAAAAACAGTTTCTTTACTTTTCATCT
AGTTTGGGCTTTCATTTGTGGGAGCTGGATGCAGCTGCAAATCTGCTACGTCTCAAATATTTAATCCATGAAGACTTATT
TGGTAAGGTAAGTTACCTAACCAAAACCATTTCTTTAGACCACAATATTATGGAAATGTTTCGGTTACCCTATCAGCAAG
AAATCCTTTATTCTTATCAGAAAAAAATGACTGTGAACCTATCTAAAAGAATACAAAGAGCTCTTTTAGCTAGACACCCG
AAATGGCTACGACGACAAGAAAAGGCTTACTTATCAGGCTATAATTTACTTATGTTAACAACTGATGCTTTTTATCCTCA
ATGGAGACCAGTTCAATCTTCCAGCGGTTTTTGTCAAATTAAAGGAAATCTTCGCCCTTATTATGAAAGTTTTAAAGTCT
ATTATAAAAAAGAAAAGGATAAGAAGGTGCAAACGCTTTTTTCACCAAAATATTATGTTAAAATGGATAGTAATAGAAAA
TGA

Domains

Predicted by InterProScan.

• Competence protein CoiA-like family (CoiA_nuc) (19-265)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus mitis NCTC 12261	42.903	96.875	0.416
coiA	Streptococcus pneumoniae Rx1	41.613	96.875	0.403
coiA	Streptococcus pneumoniae D39	41.613	96.875	0.403
coiA	Streptococcus pneumoniae R6	41.613	96.875	0.403
coiA	Streptococcus pneumoniae TIGR4	41.613	96.875	0.403
coiA	Lactococcus lactis subsp. cremoris KW2	39.329	100	0.403