Detailed information NTG0247432

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: CO204_RS07345
• Genome accession: NZ_CP023477
• Coordinates: 1442359..1444593 (-)
• Length: 744 a.a.
• NCBI ID: WP_002267862.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain LAR01
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1437359..1449593

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CO204_RS07325 (CO204_07290)	-	1438070..1439125 (-)	1056	WP_019313139.1	serine hydrolase	-
CO204_RS07330 (CO204_07295)	sodA	1439581..1440192 (-)	612	WP_106006796.1	superoxide dismutase SodA	-
CO204_RS07335 (CO204_07300)	holA	1440339..1441379 (-)	1041	WP_019313137.1	DNA polymerase III subunit delta	-
CO204_RS07340 (CO204_07305)	-	1441547..1442173 (-)	627	WP_002264731.1	DUF805 domain-containing protein	-
CO204_RS07345 (CO204_07310)	comEC/celB	1442359..1444593 (-)	2235	WP_002267862.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
CO204_RS07350 (CO204_07315)	-	1444583..1445263 (-)	681	WP_002267104.1	helix-hairpin-helix domain-containing protein	-
CO204_RS07355 (CO204_07320)	-	1445403..1446155 (-)	753	WP_002264733.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
CO204_RS07360 (CO204_07325)	-	1446294..1447229 (+)	936	WP_019313136.1	polysaccharide deacetylase family protein	-
CO204_RS07365 (CO204_07330)	-	1447318..1447830 (+)	513	WP_002261919.1	HXXEE domain-containing protein	-
CO204_RS07370 (CO204_07335)	-	1447876..1448895 (+)	1020	WP_019313135.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 744 a.a.
• Molecular weight: 85576.01 Da
• Isoelectric Point: 10.0891

>NTDB_id=247432 CO204_RS07345 WP_002267862.1 1442359..1444593(-) (comEC/celB) [Streptococcus mutans strain LAR01]
MLIRFFPLKPIYLAFLTVLLYFCIHCFSFLPVGLFILALVFLVFQYDRQICIKTLLFLLPFAAFFFYFHQKRQSEYQIVP
RQVQKLIIIPDTLSVNGDNLSFRAKSGHWTYQVFYKLKSETEKHYFEQLWQTAEIQVTADVVEAEEQRNFKGFDYRNYLK
MQGIYRIVNVTDIKTIKLSSKRFWFARLHEWRRRALVSIQSKFPDPMKHYMTGLLFGYLDKSFDEMNAIYSSLGIIHLFA
LSGMQVSFFIGKFRYLGLRLGIRQEYMNAIQLPFSLLYAGLTGFAVSVVRSLIQSNLTHFGFKKQDNFALTLFVMFFLIP
NFLLTTGGVLSFAYAFILIMIDFETLSLLKRILFQTFSLSLGILPLLMWYFSSFQPLSILLTILFSFIFDNLMLPFLTLA
YFLSPFVSLACFNPAFRLLERIIVQIHLIFSRPFILGSPTLPILLLLLCLLALLYDFRQKKRVVLVLSSILALLFFISKN
PLTNEVTIVDIGQGDSILLRDISSKTILIDVGGKVTFGQTDKWRRRISDTNAEKTLIPYLKSRGIDKIDQLVLTHTDTDH
MGDMEVVAKAFHVGEVLVSPGSLTKANFVSKLRRMKVKVHITKPGETLSIMGSHLQVLYPLKIGDGGNNDSIVLYGRLLG
LNFLFTGDLEKEGEAELLKTYPNLKVDVLKAGHHGSKGSSSPELLAQIEPKIALISAGKNNRYKHPHQETLDRFAQIKSR
IYRTDQEGAIRFKGLKHWQIETVR

Nucleotide

• Length: 2235 bp

>NTDB_id=247432 CO204_RS07345 WP_002267862.1 1442359..1444593(-) (comEC/celB) [Streptococcus mutans strain LAR01]
GTGTTGATTAGGTTTTTTCCTCTCAAACCAATCTATTTAGCCTTTTTAACTGTTTTGCTTTATTTTTGTATTCACTGCTT
TTCTTTTTTGCCAGTTGGCTTATTTATTTTAGCTTTAGTCTTTCTTGTTTTTCAATATGATAGGCAAATCTGTATCAAAA
CACTTTTGTTTTTATTGCCTTTTGCCGCTTTCTTTTTCTATTTTCACCAAAAAAGGCAAAGCGAGTATCAAATAGTACCC
AGACAGGTTCAAAAGTTAATTATCATTCCAGATACGCTTAGTGTCAATGGAGATAACTTAAGTTTTCGAGCAAAATCAGG
TCATTGGACTTATCAGGTCTTTTATAAATTAAAATCTGAAACAGAGAAACATTATTTTGAACAATTATGGCAGACAGCAG
AAATTCAAGTGACAGCGGATGTTGTAGAAGCAGAAGAGCAGCGTAATTTCAAGGGATTCGATTATAGAAACTATTTAAAG
ATGCAGGGAATTTACCGAATTGTTAATGTTACAGACATTAAAACAATTAAACTGAGTTCTAAACGCTTCTGGTTTGCTCG
TTTGCATGAATGGCGACGAAGAGCTTTGGTATCTATTCAGTCAAAATTTCCAGACCCCATGAAACACTATATGACTGGTC
TGCTTTTTGGCTATTTAGATAAATCCTTTGATGAAATGAATGCTATTTATTCTAGCTTAGGTATTATTCACCTTTTTGCT
TTGTCAGGTATGCAGGTTAGTTTTTTCATTGGGAAATTTCGTTATTTGGGCTTGCGTTTAGGTATTAGACAGGAATACAT
GAATGCTATTCAGCTGCCCTTTTCTTTGCTTTATGCTGGTTTGACTGGCTTTGCAGTATCCGTTGTGCGTAGTTTGATTC
AAAGTAATCTTACTCATTTTGGTTTTAAAAAGCAGGATAACTTTGCTCTAACCTTATTTGTTATGTTTTTCCTGATACCC
AATTTCTTATTAACAACAGGAGGTGTGCTTAGTTTTGCCTATGCTTTTATTCTAATCATGATTGATTTTGAGACTTTGTC
ACTCTTAAAGCGGATTCTATTTCAAACCTTTTCTCTTTCTTTAGGGATTTTACCGTTATTGATGTGGTATTTTAGCAGTT
TTCAGCCCTTGTCTATCCTATTAACTATCCTCTTTTCTTTTATTTTTGATAACTTGATGTTGCCTTTTTTGACACTTGCT
TATTTTCTGTCACCTTTTGTATCACTTGCCTGCTTCAATCCAGCTTTTAGATTATTAGAAAGAATAATTGTTCAAATTCA
CCTAATCTTTAGTCGTCCTTTTATTTTGGGCAGTCCGACTTTGCCTATTCTCTTACTTTTATTGTGCCTTTTAGCTTTAC
TCTATGATTTTCGTCAGAAAAAAAGGGTAGTGTTAGTACTTAGTAGCATTCTCGCCCTGTTATTTTTCATCAGTAAAAAT
CCTTTGACTAATGAAGTGACTATTGTTGATATTGGTCAGGGGGATAGTATTCTTCTTCGGGATATCAGCAGTAAGACTAT
TTTAATTGATGTAGGAGGAAAAGTAACCTTTGGACAGACTGATAAATGGCGGCGGCGTATCAGTGATACTAATGCTGAAA
AGACTTTGATTCCCTATCTCAAAAGCAGAGGCATTGATAAGATTGACCAATTGGTTTTGACTCATACTGACACGGATCAT
ATGGGAGATATGGAAGTGGTGGCAAAGGCCTTTCATGTTGGGGAAGTTTTAGTTAGTCCAGGCAGTTTAACTAAGGCAAA
TTTTGTCAGTAAATTGAGAAGAATGAAAGTTAAGGTACACATCACTAAGCCAGGGGAGACATTATCCATTATGGGGAGTC
ATTTACAGGTACTCTATCCGTTGAAAATAGGTGATGGTGGTAATAATGACTCTATCGTTCTTTATGGACGTTTGCTAGGC
TTAAATTTTCTCTTTACAGGAGATTTGGAAAAAGAAGGAGAAGCAGAATTGCTAAAGACTTATCCCAATTTAAAAGTTGA
TGTCTTAAAAGCTGGACATCATGGTTCAAAAGGTTCTTCTTCACCTGAATTATTAGCTCAAATAGAGCCTAAAATTGCTC
TTATCTCGGCAGGAAAGAACAATCGTTATAAACATCCCCATCAGGAGACACTGGACAGATTTGCGCAAATAAAAAGTCGG
ATTTATCGGACGGATCAAGAGGGTGCCATTCGTTTTAAGGGTCTTAAGCATTGGCAGATTGAGACTGTGCGATAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (214-460)

• Domain of unknown function (DUF4131) (DUF4131) (30-174)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-698)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	51.213	99.731	0.511
comEC/celB	Streptococcus mitis SK321	51.282	99.597	0.511
comEC/celB	Streptococcus pneumoniae TIGR4	50.806	100	0.508
comEC/celB	Streptococcus pneumoniae Rx1	50.134	100	0.501
comEC/celB	Streptococcus pneumoniae D39	50.134	100	0.501
comEC/celB	Streptococcus pneumoniae R6	50.134	100	0.501
comEC	Lactococcus lactis subsp. cremoris KW2	46.309	100	0.464