Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   CO204_RS01485 Genome accession   NZ_CP023477
Coordinates   281497..282189 (+) Length   230 a.a.
NCBI ID   WP_002262121.1    Uniprot ID   -
Organism   Streptococcus mutans strain LAR01     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 276497..287189
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO204_RS01465 (CO204_01465) - 276609..279221 (-) 2613 WP_106006671.1 ABC transporter permease -
  CO204_RS01470 (CO204_01470) - 279223..279930 (-) 708 WP_002265123.1 ABC transporter ATP-binding protein -
  CO204_RS01475 (CO204_01475) - 280037..280612 (+) 576 WP_002265122.1 TetR/AcrR family transcriptional regulator -
  CO204_RS01480 (CO204_01480) - 280605..281141 (+) 537 WP_002262122.1 YceD family protein -
  CO204_RS01485 (CO204_01485) covR 281497..282189 (+) 693 WP_002262121.1 response regulator GcrR Regulator
  CO204_RS01490 (CO204_01490) nrdR 282557..283048 (+) 492 WP_002262120.1 transcriptional regulator NrdR -
  CO204_RS01495 (CO204_01495) - 283035..284204 (+) 1170 WP_106006672.1 DnaD domain protein -
  CO204_RS01500 (CO204_01500) dnaI 284205..285104 (+) 900 WP_002265120.1 primosomal protein DnaI -
  CO204_RS01505 (CO204_01505) der 285117..286427 (+) 1311 WP_002287707.1 ribosome biogenesis GTPase Der -
  CO204_RS01510 (CO204_01510) - 286502..287128 (+) 627 WP_002265453.1 hypothetical protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26739.72 Da        Isoelectric Point: 4.9899

>NTDB_id=247404 CO204_RS01485 WP_002262121.1 281497..282189(+) (covR) [Streptococcus mutans strain LAR01]
MAKDILIIEDEKKLAKFVSLELQHEGYEVEVTYDGRSGLERALEKDFDLILLDLMLPEMDGYEVIRRLQLEKTTYVIIIT
ARDSIMDIVTGLDRGADGYIVKPFAIEELLARVRAIFRRQDIEKAKHSSKNDTTYRDLKLDVHNRAAIRNGETIPLTKRE
FDLLNALVENINQVMTREELLARVWKYDQEAETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYIIRENN

Nucleotide


Download         Length: 693 bp        

>NTDB_id=247404 CO204_RS01485 WP_002262121.1 281497..282189(+) (covR) [Streptococcus mutans strain LAR01]
ATGGCTAAGGACATTTTAATTATTGAAGATGAAAAAAAACTTGCAAAGTTTGTTTCTTTAGAATTACAACATGAAGGATA
TGAGGTTGAAGTGACATATGATGGGCGTTCTGGCCTGGAAAGAGCACTTGAAAAAGATTTCGATCTCATCCTTCTTGATT
TAATGTTACCAGAGATGGACGGGTATGAAGTGATTCGTCGTTTACAATTGGAAAAGACAACTTATGTTATTATTATCACT
GCTCGTGACTCCATTATGGATATTGTGACTGGTCTTGATCGTGGAGCAGATGGTTATATCGTTAAACCATTTGCTATTGA
AGAATTACTAGCTCGTGTTCGTGCCATATTTCGTCGTCAAGATATTGAGAAAGCTAAGCATTCTTCTAAAAATGATACTA
CCTATCGTGATTTGAAATTAGATGTTCATAACCGAGCTGCCATTAGAAATGGTGAGACAATTCCTTTAACTAAACGTGAA
TTTGATTTATTAAATGCTCTTGTAGAAAATATCAATCAAGTTATGACTAGAGAAGAGCTTTTGGCCCGTGTTTGGAAGTA
TGATCAAGAAGCTGAAACTAATGTTGTCGATGTTTATATTCGCTATCTTCGTGGGAAGATTGATGTTCCCGGTAAAGAAA
GCTATATTCAGACTGTCCGCGGCATGGGGTATATCATTCGCGAAAATAATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

78.07

99.13

0.774
  covR Lactococcus lactis subsp. lactis strain DGCC12653

63.436

98.696

0.626
  vicR Streptococcus mutans UA159

42.857

100

0.43
  micA Streptococcus pneumoniae Cp1015

41.631

100

0.422

Multiple sequence alignment