Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   TBD_RS00050 Genome accession   NC_007404
Coordinates   11993..13057 (-) Length   354 a.a.
NCBI ID   WP_041432812.1    Uniprot ID   -
Organism   Thiobacillus denitrificans ATCC 25259     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 6993..18057
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TBD_RS00030 (Tbd_0008) - 7358..8500 (-) 1143 WP_011310521.1 rhodanese-like domain-containing protein -
  TBD_RS00035 (Tbd_0009) - 8567..8959 (-) 393 WP_011310522.1 hypothetical protein -
  TBD_RS00040 (Tbd_0010) topA 8962..11535 (-) 2574 WP_011310523.1 type I DNA topoisomerase -
  TBD_RS00045 (Tbd_0011) - 11542..11988 (-) 447 WP_011310524.1 DUF494 domain-containing protein -
  TBD_RS00050 (Tbd_0012) dprA 11993..13057 (-) 1065 WP_041432812.1 DNA-processing protein DprA Machinery gene
  TBD_RS00055 (Tbd_0013) - 13054..14250 (-) 1197 WP_041432128.1 LysM peptidoglycan-binding domain-containing protein -
  TBD_RS00060 (Tbd_0014) def 14400..14933 (+) 534 WP_011310527.1 peptide deformylase -
  TBD_RS00065 (Tbd_0015) fmt 14943..15872 (+) 930 WP_011310528.1 methionyl-tRNA formyltransferase -
  TBD_RS00070 (Tbd_0016) rsmB 15974..17230 (+) 1257 WP_011310529.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  TBD_RS00075 (Tbd_0017) - 17235..17837 (+) 603 WP_011310530.1 DUF4390 domain-containing protein -

Sequence

Protein


Download         Length: 354 a.a.        Molecular weight: 36215.57 Da        Isoelectric Point: 5.8986

>NTDB_id=24657 TBD_RS00050 WP_041432812.1 11993..13057(-) (dprA) [Thiobacillus denitrificans ATCC 25259]
MSATEVWLRLALAPGVGNAALLRLLTAFGSPEAVLTSGRSALAAHLSSAQCDAVLGAPDPAQLDAALAWLEQPGNSLMTL
GDADYPAALLEIADPPAVLYCKGRRELLGRPALGIVGSRNATPQGLRDAEAFALALSNAGLTVISGLALGIDAAAHRGGL
AGAASSVAVIGTGLDRIYPARNKALAHELAANGLVVSEFALGTPPLPGHFPRRNRLISGLSRGVLVVEAAPDSGSLITAR
VAAEQGREVFAIPGSIHSPLARGCHALIKQGAKLVESAADVLDELAWQQRLSPPVLPESEPDPVLDALDGAPTTLDSLAQ
KTGLTLDALSAKLLALELDGRIAALPGGRYQKIH

Nucleotide


Download         Length: 1065 bp        

>NTDB_id=24657 TBD_RS00050 WP_041432812.1 11993..13057(-) (dprA) [Thiobacillus denitrificans ATCC 25259]
CTGAGCGCGACCGAGGTCTGGCTGCGTCTGGCCCTCGCCCCGGGGGTCGGCAACGCGGCGCTGCTTCGCCTGCTGACGGC
CTTCGGTTCACCGGAGGCCGTTTTGACGTCGGGCCGCAGCGCGCTCGCCGCCCATCTTTCCTCCGCGCAGTGCGACGCGG
TGCTCGGCGCGCCCGATCCCGCGCAGCTCGACGCCGCGCTCGCCTGGCTCGAGCAGCCGGGCAACTCGCTCATGACGCTC
GGCGACGCGGACTATCCCGCCGCGCTGCTCGAGATCGCCGATCCGCCGGCCGTCCTCTACTGCAAGGGCCGCCGCGAACT
CCTGGGCCGGCCCGCGCTCGGCATCGTCGGCAGCCGCAACGCCACGCCGCAGGGGCTGCGTGACGCCGAGGCCTTCGCGC
TCGCGCTCTCGAACGCAGGACTCACGGTGATCAGCGGCCTCGCGCTCGGGATCGACGCCGCGGCGCACCGCGGTGGCCTG
GCCGGCGCCGCGTCGAGCGTCGCCGTCATCGGCACCGGCCTCGACCGCATCTACCCGGCGCGCAACAAGGCGCTCGCCCA
CGAACTCGCCGCGAACGGCCTGGTCGTCTCCGAGTTCGCACTCGGCACGCCGCCGCTGCCCGGCCACTTCCCCCGCCGCA
ACCGCCTGATCAGCGGCCTGAGCCGCGGCGTGCTCGTGGTCGAGGCCGCGCCCGACAGCGGCTCGCTGATCACCGCGCGC
GTCGCGGCCGAGCAGGGGCGCGAGGTGTTCGCGATCCCCGGATCGATCCACTCGCCGCTCGCGCGCGGCTGCCATGCGCT
GATCAAGCAGGGCGCCAAGCTCGTCGAATCGGCCGCCGACGTGCTCGACGAACTCGCGTGGCAGCAGCGACTCTCACCGC
CGGTGCTGCCGGAAAGCGAGCCCGATCCGGTCCTCGACGCCCTCGACGGCGCGCCGACGACGCTCGATTCGCTAGCGCAA
AAGACCGGGTTGACGCTAGATGCGCTTTCCGCCAAGCTGTTGGCGCTCGAACTGGACGGTCGCATCGCGGCCCTGCCCGG
CGGGCGTTACCAGAAAATTCACTGA

Domains

Predicted by InterproScan.

DprA winged helix domain (DprA_WH)

(297-348)

DNA recombination-mediator protein A (DNA_processg_A)

(70-276)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Neisseria meningitidis MC58

44.33

100

0.486
  dprA Neisseria meningitidis strain C311

44.33

100

0.486
  dprA Neisseria gonorrhoeae strain FA1090

43.636

100

0.475
  dprA Neisseria gonorrhoeae MS11

43.117

100

0.469
  dprA Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

43.575

100

0.441
  dprA Vibrio campbellii strain DS40M4

42.857

100

0.432
  dprA Vibrio cholerae strain A1552

41.828

100

0.427
  dprA Legionella pneumophila strain ERS1305867

49.492

83.333

0.412
  dprA Thermus thermophilus HB27

41.379

98.305

0.407
  dprA Acinetobacter baylyi ADP1

38.936

100

0.393
  dprA Glaesserella parasuis strain SC1401

41.27

88.983

0.367

Multiple sequence alignment