Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   AOY83_RS03830 Genome accession   NZ_CP028745
Coordinates   789699..790358 (-) Length   219 a.a.
NCBI ID   WP_105458571.1    Uniprot ID   -
Organism   Escherichia coli strain A30     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 784699..795358
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AOY83_RS03805 (AOY83_04055) yqiA 784767..785348 (+) 582 WP_105458573.1 esterase YqiA -
  AOY83_RS03810 (AOY83_04060) parE 785377..787269 (+) 1893 WP_000195296.1 DNA topoisomerase IV subunit B -
  AOY83_RS03815 (AOY83_04065) ygiN 787317..787631 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  AOY83_RS03820 (AOY83_04070) mdaB 787662..788243 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  AOY83_RS03825 (AOY83_04075) qseC 788353..789702 (-) 1350 WP_240767669.1 quorum sensing histidine kinase QseC -
  AOY83_RS03830 (AOY83_04080) ciaR 789699..790358 (-) 660 WP_105458571.1 quorum sensing response regulator transcription factor QseB Regulator
  AOY83_RS03835 (AOY83_04085) ygiW 790510..790902 (+) 393 WP_096251400.1 OB fold stress tolerance protein YgiW -
  AOY83_RS03840 (AOY83_04090) ygiV 790954..791436 (+) 483 WP_105458570.1 GyrI-like domain-containing protein -
  AOY83_RS03845 (AOY83_04095) ygiS 791545..793152 (+) 1608 WP_044186453.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24583.47 Da        Isoelectric Point: 6.7638

>NTDB_id=246278 AOY83_RS03830 WP_105458571.1 789699..790358(-) (ciaR) [Escherichia coli strain A30]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTEGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWRGKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRSNGQASNELHHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=246278 AOY83_RS03830 WP_105458571.1 789699..790358(-) (ciaR) [Escherichia coli strain A30]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGATGGCATCAAAACAGGTCTGAGTAAGATGGGTTTTAGCGT
CGACTGGTTTACGGAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCGCCTTATGACGCGGTGATCCTTGATCTCACCT
TACCGGGAATGGATGGTCGCGATATTTTACGTGAGTGGCGGGGTAAAGGTCAGCGTGAGCCAGTACTGATCCTGACTGCG
CGCGATGCTCTGGCCGAACGCGTGGAAGGTTTGCGCCTGGGGGCCGACGATTATCTGTGCAAACCTTTTGCGTTGATAGA
AGTGGCCGCGAGGCTGGAAGCACTAATGCGTCGAAGCAACGGGCAAGCCAGTAATGAGTTGCATCACGGTAACGTAATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365
  micA Streptococcus pneumoniae Cp1015

34.498

100

0.361