Detailed information NTG0024383

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: NTHI_RS05555
• Genome accession: NC_007146
• Coordinates: 1098422..1099543 (-)
• Length: 373 a.a.
• NCBI ID: WP_011272330.1
• Uniprot ID: Q4QLS5
• Organism: Haemophilus influenzae 86-028NP
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1093422..1104543

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NTHI_RS05525 (NTHI1151)	dusB	1093860..1094840 (+)	981	WP_011272326.1	tRNA dihydrouridine synthase DusB	-
NTHI_RS05530 (NTHI1152)	fis	1094834..1095133 (+)	300	WP_005647967.1	DNA-binding transcriptional regulator Fis	-
NTHI_RS05535 (NTHI1153)	smpB	1095234..1095719 (-)	486	WP_005647965.1	SsrA-binding protein SmpB	-
NTHI_RS05540 (NTHI1154)	pfkA	1095958..1096923 (-)	966	WP_011272327.1	6-phosphofructokinase	-
NTHI_RS05545 (NTHI1155)	-	1097019..1097600 (-)	582	WP_011272328.1	hypothetical protein	-
NTHI_RS05550 (NTHI1156)	yaaA	1097593..1098369 (-)	777	WP_041174750.1	peroxide stress protein YaaA	-
NTHI_RS05555 (NTHI1157)	dprA	1098422..1099543 (-)	1122	WP_011272330.1	DNA-processing protein DprA	Machinery gene
NTHI_RS05560 (NTHI1160)	leuA	1100087..1101634 (+)	1548	WP_011272331.1	2-isopropylmalate synthase	-
NTHI_RS05565 (NTHI1161)	leuB	1101797..1102873 (+)	1077	WP_011272332.1	3-isopropylmalate dehydrogenase	-
NTHI_RS05570 (NTHI1162)	leuC	1103050..1104459 (+)	1410	WP_011272333.1	3-isopropylmalate dehydratase large subunit	-

Sequence

Protein

• Length: 373 a.a.
• Molecular weight: 41653.73 Da
• Isoelectric Point: 6.4124

>NTDB_id=24383 NTHI_RS05555 WP_011272330.1 1098422..1099543(-) (dprA) [Haemophilus influenzae 86-028NP]
MNDITYTLLRLMQVPKLGGVGIDKILSNITLNELLNYDDVAFRQMGWGAIQIRRWFKPEAKFIEPALAWSQKEGNHLVNY
FSPFYPFLLKQTANFPPLLFVKGNLTALSQRQMAMVGSRYCTTYGEYWAKHFATELSLAGFTITSGLALGIDGHCHQAVV
NIQGQTIAVLGSGLEQIYPSKHQRLSAQIIENNGALVSEFLPNQAPIAANFPRRNRIISGLSVGTLVVEATEKSGSLITA
RYALEQNREVFAVPGNIQNESSQGCHRLIKQGAMLVENAKDILETLYQHSIHSQTEIDFDQIAVPNYTPPPDPRRLVEAP
SHPKLYSRIGYTPVSIDDLAEEFNLSVDVLLVQLLDLELQDLIISENGLYKRI

Nucleotide

• Length: 1122 bp

>NTDB_id=24383 NTHI_RS05555 WP_011272330.1 1098422..1099543(-) (dprA) [Haemophilus influenzae 86-028NP]
ATGAATGACATTACCTACACATTACTCCGTTTAATGCAAGTGCCTAAACTTGGCGGCGTTGGCATTGATAAAATTTTGTC
CAATATTACCTTAAATGAATTACTTAATTATGATGATGTTGCTTTCCGACAAATGGGATGGGGAGCCATTCAAATTCGCC
GTTGGTTCAAACCTGAAGCAAAATTTATTGAGCCAGCACTCGCGTGGTCACAAAAAGAGGGAAATCATTTAGTAAATTAT
TTTTCCCCTTTTTATCCCTTTTTATTGAAACAAACCGCAAACTTTCCGCCACTATTATTTGTAAAAGGAAATTTAACCGC
ACTTTCACAACGCCAAATGGCAATGGTTGGGAGCCGTTATTGCACGACTTATGGAGAATATTGGGCAAAACATTTTGCAA
CAGAACTTTCATTAGCGGGTTTTACCATAACAAGCGGTTTAGCATTAGGAATTGATGGTCATTGTCATCAGGCTGTCGTC
AATATTCAAGGGCAAACTATTGCGGTCTTAGGCAGTGGATTAGAACAAATCTATCCCTCTAAACATCAAAGATTATCAGC
ACAAATCATCGAAAATAATGGGGCATTAGTCTCTGAATTTTTACCTAACCAAGCACCTATTGCTGCTAATTTTCCACGCC
GTAATCGGATTATTAGTGGGCTTTCAGTCGGCACGCTCGTTGTTGAAGCCACCGAAAAAAGTGGATCACTTATTACTGCA
CGGTATGCGTTGGAACAAAACCGAGAGGTTTTTGCTGTGCCAGGCAATATTCAAAATGAATCAAGTCAAGGTTGTCATCG
CCTGATTAAACAAGGCGCAATGTTGGTAGAAAATGCAAAGGACATTTTGGAAACGCTCTACCAACATTCTATCCACAGCC
AAACTGAAATTGATTTTGACCAGATCGCCGTGCCTAATTACACGCCACCACCCGATCCTCGCCGATTAGTAGAAGCACCA
AGCCACCCGAAACTTTATTCACGTATTGGCTATACTCCTGTGAGCATTGATGATTTAGCTGAAGAATTTAATTTAAGTGT
CGATGTTTTACTTGTTCAATTGCTCGATCTTGAGCTACAAGATCTTATCATAAGTGAAAATGGCTTATATAAACGCATTT
AA

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (311-366)

• DNA recombination-mediator protein A (DNA_processg_A) (71-277)

3D structure

• AlphaFold DB: Q4QLS5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Haemophilus influenzae Rd KW20	98.928	100	0.989
dprA	Glaesserella parasuis strain SC1401	52.011	93.298	0.485
dprA	Vibrio campbellii strain DS40M4	43.617	100	0.44
dprA	Vibrio cholerae strain A1552	43.014	97.855	0.421
dprA	Legionella pneumophila strain ERS1305867	40.751	92.761	0.378