Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   CHY23_RS10450 Genome accession   NZ_CP022715
Coordinates   2183529..2184731 (-) Length   400 a.a.
NCBI ID   WP_005597394.1    Uniprot ID   Q6XFB0
Organism   Actinobacillus pleuropneumoniae strain KL 16     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2178529..2189731
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CHY23_RS10425 (CHY23_02111) lptE 2180329..2180823 (+) 495 WP_005597385.1 LPS assembly lipoprotein LptE -
  CHY23_RS10430 (CHY23_02112) holA 2180932..2181957 (+) 1026 WP_005612206.1 DNA polymerase III subunit delta -
  CHY23_RS10435 (CHY23_02113) yacG 2182034..2182222 (-) 189 WP_005597388.1 DNA gyrase inhibitor YacG -
  CHY23_RS10440 (CHY23_02114) coaE 2182204..2182842 (-) 639 WP_005597390.1 dephospho-CoA kinase -
  CHY23_RS10445 (CHY23_02115) - 2182864..2183502 (-) 639 WP_005597392.1 prepilin peptidase -
  CHY23_RS10450 (CHY23_02116) pilC 2183529..2184731 (-) 1203 WP_005597394.1 type II secretion system F family protein Machinery gene
  CHY23_RS10455 (CHY23_02117) pilB 2184715..2186109 (-) 1395 WP_117374128.1 GspE/PulE family protein Machinery gene
  CHY23_RS10460 (CHY23_02118) pilA 2186127..2186573 (-) 447 WP_005597397.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  CHY23_RS10465 (CHY23_02119) radA 2186755..2188134 (+) 1380 WP_005597398.1 DNA repair protein RadA -
  CHY23_RS10470 (CHY23_02120) - 2188178..2188411 (-) 234 WP_005597399.1 YgjV family protein -
  CHY23_RS10475 (CHY23_02121) folA 2188538..2189026 (-) 489 WP_005597400.1 type 3 dihydrofolate reductase -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 45588.11 Da        Isoelectric Point: 10.2885

>NTDB_id=241839 CHY23_RS10450 WP_005597394.1 2183529..2184731(-) (pilC) [Actinobacillus pleuropneumoniae strain KL 16]
MLKVYEFHWKAKNRFQQLQKGKALACHRTELERRLLAKGYSQIRIQRNFRFVTQASSESITQVIKQLALLLNAAVPLKQA
LNMLLENTYHIRIYMWLNDLNRLIESGYTMSSSLTKLNLYLAKSEIQLVRIGEQSGRLGEILQNIAVNRYQTEKLHKKIK
KIMFYPVVTLIISVALSLAMLLFIVPQFIELYSGREKPLPLITQMLFTLSLFLQHSLLQVTIVSLLAVGFFRFFAKKYRF
LTAIKNGVLSALPIFNKIVENVRIVFFSQNLGLMLKAHIRLETALNTFLATQSQDLRLQKEIENILAQLKQGYRFSESIN
ASVFGTQVVQMLAIGEQSGNVAQMCSYIGELYRQQLDDQIELLSQLLEPILMLIIGLIIGTVLIGLYLPIFDLGGLVGGG

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=241839 CHY23_RS10450 WP_005597394.1 2183529..2184731(-) (pilC) [Actinobacillus pleuropneumoniae strain KL 16]
ATGTTGAAAGTGTATGAATTCCATTGGAAAGCTAAAAATCGTTTTCAACAACTTCAGAAAGGAAAAGCGTTAGCTTGTCA
TCGAACGGAATTGGAACGGCGTTTATTAGCAAAAGGCTATTCACAGATCCGTATCCAACGTAATTTTCGTTTTGTCACAC
AGGCTTCTTCAGAATCGATTACTCAAGTAATTAAACAGTTGGCGCTTTTACTGAATGCCGCAGTCCCTTTAAAACAAGCG
CTGAATATGTTGTTAGAAAATACTTATCATATTCGGATCTATATGTGGCTGAATGATTTAAACCGTTTGATAGAATCGGG
TTATACAATGTCGTCAAGTTTAACCAAATTGAATTTATATTTGGCGAAATCGGAAATACAGCTGGTACGGATTGGCGAAC
AAAGCGGGCGATTAGGCGAAATTTTGCAAAATATTGCGGTAAATCGCTATCAAACCGAAAAATTACATAAGAAAATAAAA
AAGATAATGTTTTATCCTGTCGTCACTTTGATTATTTCCGTTGCGCTTTCTCTCGCCATGCTCCTTTTTATCGTGCCGCA
ATTTATCGAGCTGTATTCCGGTCGTGAAAAGCCGCTTCCTTTAATTACACAAATGCTATTTACATTATCGCTCTTCTTAC
AACATTCTTTATTACAGGTAACGATAGTCAGTTTATTAGCGGTCGGTTTTTTCCGTTTTTTTGCAAAAAAATATCGATTT
TTAACCGCTATAAAAAACGGGGTGTTAAGTGCTTTGCCTATTTTTAATAAGATAGTCGAAAACGTTCGTATAGTATTTTT
TAGTCAAAATCTCGGCTTGATGCTAAAAGCTCATATTCGGCTGGAAACGGCGTTAAATACCTTTCTTGCTACACAATCGC
AAGATTTGAGGTTACAAAAAGAGATAGAAAATATTTTAGCGCAATTAAAACAAGGTTATCGCTTTTCCGAAAGTATTAAT
GCGAGTGTGTTCGGTACTCAAGTAGTACAAATGCTTGCCATTGGCGAACAGAGTGGGAATGTAGCGCAGATGTGTAGCTA
TATCGGGGAGTTATATCGACAACAATTGGATGATCAGATTGAACTGTTATCGCAGCTGCTTGAGCCGATCTTAATGCTGA
TTATCGGATTAATTATCGGTACGGTTTTGATCGGATTATATTTACCGATTTTTGATTTAGGCGGACTAGTCGGAGGCGGT
TAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(267-389)

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q6XFB0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Glaesserella parasuis strain SC1401

49.874

99.25

0.495
  pilC Haemophilus influenzae Rd KW20

40

100

0.4
  pilC Haemophilus influenzae 86-028NP

39

100

0.39

Multiple sequence alignment