Detailed information NTG0241065

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: Sp14A_RS07980
• Genome accession: NZ_CP022601
• Coordinates: 1563140..1565356 (-)
• Length: 738 a.a.
• NCBI ID: WP_115131183.1
• Uniprot ID: -
• Organism: Streptococcus pluranimalium strain 14A0014
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1558140..1570356

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Sp14A_RS07950 (Sp14A_16480)	-	1559040..1559615 (-)	576	Protein_1530	MBL fold metallo-hydrolase	-
Sp14A_RS11865	-	1560007..1560791 (-)	785	Protein_1531	recombinase zinc beta ribbon domain-containing protein	-
Sp14A_RS07965 (Sp14A_16500)	-	1560953..1561714 (-)	762	WP_115130605.1	ABC transporter permease	-
Sp14A_RS07970 (Sp14A_16510)	-	1561716..1562642 (-)	927	WP_115130606.1	ABC transporter ATP-binding protein	-
Sp14A_RS11735	-	1562770..1563012 (+)	243	Protein_1534	IS982 family transposase	-
Sp14A_RS07980 (Sp14A_16520)	comEC/celB	1563140..1565356 (-)	2217	WP_115131183.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
Sp14A_RS07985 (Sp14A_16530)	-	1565364..1566035 (-)	672	WP_115130607.1	helix-hairpin-helix domain-containing protein	-
Sp14A_RS07990 (Sp14A_16540)	-	1566105..1566854 (-)	750	WP_115130608.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
Sp14A_RS07995 (Sp14A_16550)	-	1567016..1567204 (+)	189	WP_104968267.1	hypothetical protein	-
Sp14A_RS08000 (Sp14A_16560)	-	1567562..1568095 (-)	534	WP_162797781.1	isoprenylcysteine carboxyl methyltransferase family protein	-
Sp14A_RS08010 (Sp14A_16570)	-	1568352..1569110 (+)	759	WP_115130611.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
Sp14A_RS08015 (Sp14A_16580)	-	1569107..1569367 (+)	261	WP_115130612.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 738 a.a.
• Molecular weight: 83654.43 Da
• Isoelectric Point: 9.5470

>NTDB_id=241065 Sp14A_RS07980 WP_115131183.1 1563140..1565356(-) (comEC/celB) [Streptococcus pluranimalium strain 14A0014]
MLKPIYLAFLVALTYFMILTKSWGVILLALLAVIALFRQYSKKAIIQTIVILTLFVAYFTFLGNKQIQLEKQLPSQVSTL
RVIPDSISVDGDLLSARAEEGKQRYQLYYQLQTELEKEYFQNLNQLILLKVMASVEKPQGQRNFKGFDYKTYLKREGIYG
IVQVEKVNAIHTVAPQNPEEWVRLWRRKLLVHINQHFPEPMKHYMTGLLLGYLDKSFDEMSDIYTDLGIIHLFALSGMQV
GFFVGIFRTILLRLGLLREHFLYVLLPFSFIYAGLTGFTISVVRSLLQAILSQFGLRKWDNLGTTILILFLLSPHFLVTT
GGVLSFAYAFILSTLDLDTLSGCRKAVVESMVLSLGILPLLVFYFGTFQPLSILLTAFFSVIFDVFLLPLLSLVLLASPI
VSLDFFNPCFYFLESVIKWTVHLSPRPLVFGSPNLTVLLLMLISLAVVHDFWHDKKLRYCFLIVVVALFAVTKKPLENEV
TVLDVGQGDSIFIRDIRGKTLLIDTGGRVDFTQKEEWRRRQKTANAERTSIPYLKSRGISSIDQLVITHTDADHMGDMAV
LAKQFSIKEVLVSPGALTNPSFVKVLKSLKIKVGLLQAGDQIAIMGSSLQVLYPWDQGDGGNNDSLVLYGKLLDKRFLFT
GDLEVDGEKSLMMRYPNLPVDILKAGHHGSKGSSDPDFLKHIGAKVALISAGLNNRYQHPNDETLERFEVQKMMIYRTDQ
EGAIRYRGVKTWKVETVR

Nucleotide

• Length: 2217 bp

>NTDB_id=241065 Sp14A_RS07980 WP_115131183.1 1563140..1565356(-) (comEC/celB) [Streptococcus pluranimalium strain 14A0014]
ATGTTAAAGCCAATCTATTTGGCTTTTTTAGTAGCTTTGACCTATTTTATGATCTTGACCAAATCCTGGGGTGTCATTTT
GCTAGCTTTGCTTGCCGTTATCGCTTTATTCAGACAATATTCTAAAAAGGCAATTATACAGACGATTGTTATCCTTACTC
TATTTGTTGCGTATTTTACTTTTTTGGGGAACAAGCAGATTCAGCTGGAAAAGCAGCTCCCAAGTCAAGTGTCGACCTTG
CGTGTGATACCTGATAGCATTTCTGTAGATGGTGATTTATTATCTGCGCGTGCTGAAGAAGGTAAGCAAAGGTATCAGCT
TTATTATCAATTACAGACGGAGTTGGAAAAGGAATATTTTCAAAATCTTAATCAGCTGATCCTTTTAAAGGTAATGGCTT
CAGTCGAGAAGCCACAAGGTCAGCGCAATTTTAAAGGTTTTGATTATAAGACTTATTTGAAACGAGAAGGCATTTATGGG
ATCGTTCAAGTTGAGAAAGTCAACGCCATTCATACGGTTGCTCCTCAAAACCCAGAGGAATGGGTTAGACTGTGGCGGAG
AAAGCTTCTGGTCCACATCAATCAACACTTTCCTGAGCCTATGAAACATTATATGACGGGACTTTTGTTGGGGTATTTGG
ATAAGTCTTTTGACGAGATGAGTGATATCTATACGGATTTGGGGATTATTCATCTTTTTGCCCTGTCTGGCATGCAGGTG
GGCTTTTTTGTCGGTATTTTTCGGACGATCCTTTTACGTCTAGGGCTTTTGAGGGAGCATTTTTTGTATGTTCTTCTGCC
ATTTTCCTTTATTTACGCCGGTCTAACAGGATTCACGATTTCTGTGGTACGAAGCTTATTACAGGCCATTCTCAGTCAAT
TTGGCTTGCGAAAATGGGATAATTTAGGAACAACCATCTTGATATTGTTCCTGCTATCGCCCCATTTTTTGGTTACAACA
GGAGGTGTTCTATCTTTCGCTTATGCCTTCATACTGTCTACCTTAGATTTAGACACTTTGTCAGGATGCCGCAAAGCAGT
AGTAGAAAGTATGGTACTTTCACTAGGCATTCTACCCTTGTTGGTATTTTATTTCGGGACTTTTCAGCCTCTGTCAATTC
TTTTAACAGCATTCTTTTCAGTGATTTTTGATGTCTTTTTGTTACCCTTGTTAAGTCTTGTGTTATTAGCCAGTCCGATA
GTATCTCTAGACTTTTTTAATCCTTGCTTTTACTTTTTAGAATCAGTTATCAAGTGGACGGTACATCTGTCTCCTCGCCC
CTTGGTTTTTGGTAGCCCTAACTTAACTGTACTTCTATTAATGCTTATTTCTTTAGCTGTTGTACATGATTTTTGGCATG
ATAAAAAATTGAGGTACTGTTTTTTGATTGTTGTAGTTGCCTTGTTTGCTGTGACGAAAAAACCTTTAGAAAATGAGGTG
ACTGTTCTAGATGTTGGGCAAGGAGATTCGATTTTCATTAGGGATATCAGAGGGAAAACCTTGCTTATTGATACGGGAGG
CCGAGTTGATTTTACTCAGAAAGAGGAGTGGCGCAGGCGGCAGAAAACAGCTAATGCTGAACGGACATCCATCCCCTATC
TGAAAAGTCGAGGGATTTCGTCCATCGACCAACTTGTGATTACGCATACCGATGCAGACCACATGGGAGATATGGCAGTT
CTAGCCAAGCAGTTTAGTATTAAGGAAGTTTTGGTTAGTCCAGGTGCTCTGACCAATCCCTCTTTTGTAAAAGTGCTAAA
ATCATTGAAAATCAAAGTAGGATTGCTTCAAGCTGGGGATCAGATTGCGATTATGGGGTCTTCTCTTCAAGTTCTCTACC
CGTGGGATCAGGGAGATGGTGGGAATAACGATTCCTTGGTCTTATATGGAAAGTTATTAGATAAACGATTTCTTTTTACG
GGAGATTTAGAAGTTGATGGCGAAAAATCCTTGATGATGAGGTATCCCAACTTACCCGTTGATATTTTAAAAGCTGGGCA
CCATGGCTCTAAAGGATCTTCTGATCCAGACTTTTTAAAACATATCGGAGCAAAAGTCGCGTTGATTTCAGCTGGTCTTA
ATAATCGTTACCAGCATCCCAATGATGAAACCTTAGAACGCTTTGAAGTCCAAAAGATGATGATTTATAGGACCGATCAA
GAAGGAGCGATTCGTTACAGAGGTGTAAAGACTTGGAAAGTTGAAACGGTTCGTTGA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (484-692)

• Domain of unknown function (DUF4131) (DUF4131) (23-168)

• Competence protein (Competence) (208-452)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	48.645	100	0.486
comEC/celB	Streptococcus mitis NCTC 12261	48.711	99.864	0.486
comEC/celB	Streptococcus pneumoniae TIGR4	47.29	100	0.473
comEC/celB	Streptococcus pneumoniae D39	47.154	100	0.472
comEC/celB	Streptococcus pneumoniae Rx1	47.154	100	0.472
comEC/celB	Streptococcus pneumoniae R6	47.154	100	0.472
comEC	Lactococcus lactis subsp. cremoris KW2	44.28	100	0.446