Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   Sp14A_RS02060 Genome accession   NZ_CP022601
Coordinates   385618..386307 (+) Length   229 a.a.
NCBI ID   WP_115129732.1    Uniprot ID   A0A345VI01
Organism   Streptococcus pluranimalium strain 14A0014     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 380618..391307
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Sp14A_RS02035 (Sp14A_04150) - 380996..381667 (-) 672 WP_115129727.1 TrkA family potassium uptake protein -
  Sp14A_RS02040 (Sp14A_04160) - 381686..383059 (-) 1374 WP_115129728.1 potassium transporter TrkG -
  Sp14A_RS02045 (Sp14A_04170) rsmG 383084..383797 (-) 714 WP_115129729.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  Sp14A_RS02050 (Sp14A_04180) htpX 383912..384817 (+) 906 WP_115129730.1 zinc metalloprotease HtpX -
  Sp14A_RS02055 (Sp14A_04190) - 384852..385385 (+) 534 WP_115129731.1 YceD family protein -
  Sp14A_RS02060 (Sp14A_04200) covR 385618..386307 (+) 690 WP_115129732.1 response regulator transcription factor Regulator
  Sp14A_RS02065 (Sp14A_04210) - 386288..387808 (+) 1521 WP_115129733.1 HAMP domain-containing histidine kinase -
  Sp14A_RS02070 (Sp14A_04220) nrdR 388252..388725 (+) 474 WP_104968798.1 transcriptional regulator NrdR -
  Sp14A_RS02075 (Sp14A_04230) - 388725..389897 (+) 1173 WP_115129734.1 DnaD domain protein -
  Sp14A_RS02080 (Sp14A_04240) dnaI 389900..390802 (+) 903 WP_104967321.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26370.19 Da        Isoelectric Point: 4.7749

>NTDB_id=241044 Sp14A_RS02060 WP_115129732.1 385618..386307(+) (covR) [Streptococcus pluranimalium strain 14A0014]
MTKNILIIEDEKNLSRFVSLELQHEGYSVTIESNGRAGLETALDKDFDLILLDLMLPEMDGFEVTRRLQQEKSTYIIMMT
ARDSVMDIVSGLDRGADDYIIKPFAIEELLARVRAAFRRQEIEESKRNASGGASYRDLKLDPQNRSVIRGDETVPLTKRE
FDLLSALMSNMNRVMTREELLNLVWKYDEAVETNVVDVYIRYLRGKIDVSGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=241044 Sp14A_RS02060 WP_115129732.1 385618..386307(+) (covR) [Streptococcus pluranimalium strain 14A0014]
ATGACAAAAAATATTCTGATTATAGAGGATGAGAAAAATCTTTCGCGCTTCGTTTCTCTAGAATTACAGCATGAAGGGTA
TTCGGTAACCATTGAAAGTAATGGTCGCGCTGGTTTAGAAACAGCATTAGATAAAGATTTTGATTTGATTTTATTAGATT
TGATGTTGCCAGAGATGGATGGCTTTGAAGTGACACGTCGCTTACAACAAGAAAAGTCAACTTACATCATTATGATGACT
GCTAGAGACTCTGTTATGGATATTGTTTCAGGATTGGATCGTGGTGCAGACGATTATATTATCAAGCCATTTGCGATTGA
GGAACTCTTAGCGCGTGTTCGTGCTGCTTTTCGTCGTCAAGAAATTGAGGAAAGTAAACGAAATGCTTCAGGTGGAGCTA
GCTATCGTGACCTCAAATTGGATCCACAGAATCGCTCGGTTATTCGTGGGGATGAAACAGTTCCTTTAACAAAACGTGAG
TTTGATTTGTTATCTGCTTTGATGTCTAACATGAACCGTGTCATGACACGTGAAGAATTATTAAATCTTGTCTGGAAGTA
TGATGAAGCTGTAGAAACAAATGTTGTTGATGTCTACATTCGTTATCTTCGTGGCAAGATTGATGTCTCTGGTAAAGAAT
CATACATTCAAACTGTCCGTGGTATGGGTTATGTCATTCGTGAAAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A345VI01

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

80.786

100

0.808
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.544

99.563

0.672
  vicR Streptococcus mutans UA159

44.156

100

0.445
  micA Streptococcus pneumoniae Cp1015

42.308

100

0.432

Multiple sequence alignment