Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   CG712_RS02010 Genome accession   NZ_CP022547
Coordinates   381227..382597 (-) Length   456 a.a.
NCBI ID   WP_096811492.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain B59671     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 376227..387597
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CG712_RS01980 (CG712_02005) - 376374..376760 (-) 387 WP_002953113.1 DUF1934 domain-containing protein -
  CG712_RS01985 (CG712_02010) - 376852..377731 (-) 880 Protein_385 GNAT family N-acetyltransferase -
  CG712_RS01990 (CG712_02015) yidA 377939..378748 (+) 810 WP_011226081.1 sugar-phosphatase -
  CG712_RS01995 (CG712_02020) - 378750..379964 (+) 1215 WP_096811491.1 aminoacyltransferase -
  CG712_RS02000 (CG712_02025) - 380016..380377 (-) 362 Protein_388 YbaN family protein -
  CG712_RS02005 (CG712_02030) vicX 380437..381249 (-) 813 WP_011681204.1 MBL fold metallo-hydrolase Regulator
  CG712_RS02010 (CG712_02035) vicK 381227..382597 (-) 1371 WP_096811492.1 cell wall metabolism sensor histidine kinase VicK Regulator
  CG712_RS02015 (CG712_02040) vicR 382590..383297 (-) 708 WP_011226084.1 response regulator YycF Regulator
  CG712_RS02020 (CG712_02045) - 383824..384591 (+) 768 WP_011226085.1 amino acid ABC transporter ATP-binding protein -
  CG712_RS02025 (CG712_02050) - 384603..385436 (+) 834 WP_002953142.1 transporter substrate-binding domain-containing protein -
  CG712_RS02030 (CG712_02055) - 385454..386152 (+) 699 WP_022096755.1 amino acid ABC transporter permease -
  CG712_RS02035 (CG712_02060) - 386164..386814 (+) 651 WP_011226088.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 456 a.a.        Molecular weight: 51902.47 Da        Isoelectric Point: 6.1017

>NTDB_id=240551 CG712_RS02010 WP_096811492.1 381227..382597(-) (vicK) [Streptococcus thermophilus strain B59671]
MTSIGLNITSFELALLFMLLFVAFYFIFLAYRDYQQVKNIRKLTKRVKSLMAGNYNEKLCIKGDSELLELANSLNDLSDV
FRLTHENLIQEKNRLSSVLSYMSDGVIATNRLGQITMINSTAQRLLNLDRETAIQMSILDILDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFVLIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALNE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLNVEMTNFTAFMTYILNRFGQIKSQETNPGKSYEIIRDYPVNSI
WVEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDTQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHNGFIWAKSEYGKGSTFTIVLPYDQDAMMVDENGRCSRNDLRIRV

Nucleotide


Download         Length: 1371 bp        

>NTDB_id=240551 CG712_RS02010 WP_096811492.1 381227..382597(-) (vicK) [Streptococcus thermophilus strain B59671]
ATGACTAGTATTGGCTTAAATATTACAAGCTTTGAACTGGCCTTACTCTTTATGCTCCTCTTTGTTGCTTTCTATTTCAT
TTTTCTAGCTTATCGTGATTATCAACAGGTCAAAAATATCCGAAAGTTGACTAAGAGAGTCAAATCCCTTATGGCAGGTA
ATTATAATGAAAAATTATGCATAAAGGGAGATTCAGAGCTTTTAGAGCTAGCTAATAGCTTGAATGATTTGTCGGACGTC
TTTCGTTTGACACATGAAAATCTAATCCAGGAAAAAAACCGCTTATCATCTGTTCTTTCGTACATGAGTGACGGGGTTAT
TGCGACCAATCGCCTTGGTCAGATTACTATGATTAATAGTACTGCCCAACGCTTGTTGAATTTAGATCGCGAAACTGCGA
TTCAGATGTCTATTTTGGATATATTAGATGGTGAGAATCCCTATACCTATAGTGAATTGTTGTCTAAGACACCCGAAATC
CATCTGTCGCGTCGAGATGCTAACGATGAATTTGTGACGCTACGTGTTAATTTTGTATTAATTCGTAAGGAATCTGGTTT
TATTTCAGGTCTGGTAGCCGTTCTTCATGATGCCACTGAGCAGGAAAAAGAAGAGCGCGAACGCCGTCTCTTCGTATCAA
ATGTTAGTCACGAATTGCGGACGCCTTTAACTTCTGTGAAATCCTATCTTGAAGCGCTTGATGATGGTGCTCTCAACGAA
GAGATTGCTCCAAACTTTATCAAAGTTTCTTTAGATGAAACCAACCGCATGATGCGTATGATTTCTGACCTCTTGGCATT
ATCTCGAATTGACAATAAAAGCACACAGCTTAATGTTGAAATGACAAACTTTACAGCCTTTATGACCTATATCTTGAATC
GGTTTGGTCAAATTAAGAGTCAAGAAACTAATCCAGGTAAGTCTTATGAAATCATTCGAGATTACCCAGTAAACTCTATT
TGGGTGGAAATTGATACTGATAAGATGACCCAGGTCATAGATAATATACTTAATAATGCCATCAAGTATTCTCCTGATGG
TGGGAAAATTACAGTATCTATGAAAACGACAGACACTCAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGAATTCCTA
AAAAAGATTTACCTCTGATTTTTGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCTCAGGGTGGAACAGGACTT
GGCTTATCCATTGCAAAAGAAATTGTTAAACAACATAATGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGATCAAC
TTTTACAATTGTGCTTCCATATGACCAGGACGCAATGATGGTCGATGAAAATGGGAGATGTAGTAGAAATGACCTCAGAA
TTAGGGTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

PAS fold (PAS)

(94-197)

HAMP domain (HAMP)

(37-79)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.155

90.789

0.673
  micB Streptococcus pneumoniae Cp1015

65.596

95.614

0.627

Multiple sequence alignment