Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   CGZ53_RS02150 Genome accession   NZ_CP022435
Coordinates   398371..399057 (+) Length   228 a.a.
NCBI ID   WP_100911922.1    Uniprot ID   -
Organism   Streptococcus uberis strain NZ01     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 393371..404057
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CGZ53_RS02125 (CGZ53_02120) ktrB 393594..394985 (-) 1392 WP_269441091.1 potassium uptake transporter channel subunit KtrB -
  CGZ53_RS02130 (CGZ53_02125) rsmG 395057..395770 (-) 714 WP_012657909.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  CGZ53_RS02135 (CGZ53_02130) - 395917..396474 (+) 558 WP_012657910.1 LemA family protein -
  CGZ53_RS02140 (CGZ53_02135) htpX 396509..397402 (+) 894 WP_012657911.1 zinc metalloprotease HtpX -
  CGZ53_RS02145 (CGZ53_02140) - 397615..398148 (+) 534 WP_012657912.1 YceD family protein -
  CGZ53_RS02150 (CGZ53_02145) covR 398371..399057 (+) 687 WP_100911922.1 two-component system response regulator CovR Regulator
  CGZ53_RS02155 (CGZ53_02150) - 399061..400563 (+) 1503 WP_100911923.1 ATP-binding protein -
  CGZ53_RS02160 (CGZ53_02155) nrdR 400726..401220 (+) 495 WP_012657916.1 transcriptional regulator NrdR -
  CGZ53_RS02165 (CGZ53_02160) - 401204..402400 (+) 1197 WP_046387903.1 DnaD domain protein -
  CGZ53_RS02170 (CGZ53_02165) dnaI 402401..403303 (+) 903 WP_100911924.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26669.69 Da        Isoelectric Point: 4.6540

>NTDB_id=239371 CGZ53_RS02150 WP_100911922.1 398371..399057(+) (covR) [Streptococcus uberis strain NZ01]
MTKKILIVEDEKNLARFVSLELQHECYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIETEKKAPNQGIYRDLVLNPQNRSVNRGDDEISLTKREY
DLLNILMSNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDMPGRESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=239371 CGZ53_RS02150 WP_100911922.1 398371..399057(+) (covR) [Streptococcus uberis strain NZ01]
ATGACAAAGAAAATTTTAATCGTTGAAGATGAGAAAAATCTTGCGAGATTTGTATCTTTAGAATTACAACATGAATGTTA
TGAAGTAACAGTCGAGGTAAATGGGCGTGAAGGTTTAGAAACGGCTCTTGAAAAAGACTTTGATTTAATCCTTTTAGATT
TAATGTTACCTGAAATGGATGGTTTTGAAGTGACACGTCGCTTACAGACTGAGAAAACAACCTATATCATGATGATGACT
GCACGTGATTCTATCATGGATGTCGTGGCAGGTTTAGACCGTGGTGCGGATGATTATATTGTTAAACCATTTGCCATTGA
AGAGTTATTAGCACGTATCAGAGCGATTTTCCGTCGTCAAGACATTGAAACAGAGAAGAAAGCTCCCAATCAAGGAATCT
ATCGTGATTTAGTTTTAAATCCACAAAATCGTTCAGTCAACCGTGGTGATGATGAAATTTCATTAACAAAACGTGAATAT
GATTTGTTAAATATTCTTATGTCAAATATGAACCGTGTTATGACACGTGAAGAATTATTATCAAACGTTTGGAAATATGA
CGAAGCAGTGGAAACAAATGTTGTTGATGTCTACATTCGTTACCTTCGTGGAAAAATTGACATGCCTGGAAGAGAGTCAT
ACATTCAAACAGTTCGTGGAATGGGATACGTAATTCGCGAGAAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.969

100

0.833
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.52

99.561

0.662
  vicR Streptococcus mutans UA159

43.29

100

0.439
  micA Streptococcus pneumoniae Cp1015

43.043

100

0.434

Multiple sequence alignment