Detailed information NTG0023860

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: LPL_RS12725
• Genome accession: NC_006369
• Coordinates: 2874286..2875371 (+)
• Length: 361 a.a.
• NCBI ID: WP_011216473.1
• Uniprot ID: -
• Organism: Legionella pneumophila str. Lens
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 2869286..2880371

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LPL_RS12700 (lpl2515)	-	2869679..2870428 (-)	750	WP_011216469.1	type II CAAX prenyl endopeptidase Rce1 family protein	-
LPL_RS12705 (lpl2516)	rsmB	2870425..2871708 (-)	1284	WP_011216470.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
LPL_RS12710 (lpl2517)	fmt	2871705..2872649 (-)	945	WP_011216471.1	methionyl-tRNA formyltransferase	-
LPL_RS12715 (lpl2518)	def	2872646..2873158 (-)	513	WP_010948295.1	peptide deformylase	-
LPL_RS12720 (lpl2519)	-	2873252..2874289 (+)	1038	WP_011216472.1	LysM peptidoglycan-binding domain-containing protein	-
LPL_RS12725 (lpl2520)	dprA	2874286..2875371 (+)	1086	WP_011216473.1	DNA-processing protein DprA	Machinery gene
LPL_RS12730 (lpl2521)	-	2875361..2875798 (+)	438	WP_011216474.1	DUF494 family protein	-
LPL_RS12735 (lpl2522)	topA	2875877..2878156 (+)	2280	WP_011216475.1	type I DNA topoisomerase	-
LPL_RS12740 (lpl2523)	-	2878257..2880230 (-)	1974	WP_011216476.1	acyltransferase family protein	-

Sequence

Protein

• Length: 361 a.a.
• Molecular weight: 39587.77 Da
• Isoelectric Point: 7.0520

>NTDB_id=23860 LPL_RS12725 WP_011216473.1 2874286..2875371(+) (dprA) [Legionella pneumophila str. Lens]
MNNLQPLLALNRMKKIGPRTVLKLQKRWPDLNLMFQLSSVALEEAGLPSWLAQTIKNFDPDFIKTDLDWLSSSENHHILT
WDSPYYPALLKEIADPPFILYAKGELSALTQPNLAIVGSRNASVTGNENARAFSREISRHGVSIVSGLALGIDAHAHLGC
LEEGGKTIAVLGTGIDCIYPRRHLKLAEQITENGLLLSEFPLKSPPIAGHFPLRNRIISGLSLCILVIEAAIKSGSLITA
RMALEQNRDVLAIPGSIHNPLARGCHYLLQQGAKLVTSVADVLDELKIEHHQFTSNKPIFSLASGKENLVKFIGFETTTI
DQIIDRSGYGMEQVTSGLAELELKGAVMAVPGGYIRCEYER

Nucleotide

• Length: 1086 bp

>NTDB_id=23860 LPL_RS12725 WP_011216473.1 2874286..2875371(+) (dprA) [Legionella pneumophila str. Lens]
ATGAATAATCTGCAACCCCTCCTCGCCTTAAACAGGATGAAAAAAATTGGCCCCCGAACCGTATTAAAACTGCAAAAAAG
ATGGCCTGATTTAAACCTTATGTTCCAACTGTCTAGTGTTGCTCTGGAAGAAGCGGGCTTGCCATCCTGGTTGGCACAAA
CCATAAAAAATTTTGATCCGGACTTTATAAAAACTGACTTGGACTGGTTAAGTTCATCAGAAAATCATCATATTTTAACT
TGGGACTCCCCCTATTATCCCGCATTGCTCAAAGAAATAGCCGATCCTCCCTTCATTTTATACGCTAAAGGTGAGCTGTC
CGCTTTGACACAGCCCAACCTGGCTATTGTTGGAAGTCGCAATGCTTCTGTAACAGGAAACGAGAATGCCCGAGCATTCT
CCAGGGAAATTTCCAGGCATGGGGTAAGCATAGTGAGTGGTTTAGCCTTGGGAATTGATGCTCATGCTCATTTAGGTTGT
CTGGAAGAAGGCGGCAAAACGATAGCGGTCTTAGGTACGGGAATTGATTGTATCTATCCGCGCCGGCATTTAAAATTAGC
TGAGCAAATTACAGAGAATGGTTTATTATTAAGCGAATTTCCTTTAAAAAGTCCACCAATTGCTGGACATTTTCCACTCA
GAAATCGTATAATAAGCGGTCTATCATTATGCATTTTGGTTATCGAGGCAGCAATTAAAAGCGGTTCTTTAATTACAGCA
AGAATGGCTCTGGAACAAAACAGAGATGTATTGGCTATTCCCGGATCGATTCATAACCCGTTAGCCAGGGGCTGCCACTA
CTTATTGCAACAGGGTGCGAAATTAGTAACTTCAGTGGCTGATGTTCTTGATGAGCTAAAAATTGAGCACCATCAGTTCA
CTTCTAATAAACCAATTTTTTCCCTTGCCAGCGGTAAGGAAAACCTAGTAAAGTTCATTGGTTTTGAAACTACGACTATC
GATCAAATCATTGATCGTAGCGGATATGGCATGGAACAAGTCACGAGTGGACTGGCTGAACTAGAATTGAAAGGGGCTGT
GATGGCAGTGCCCGGTGGCTACATAAGGTGTGAATATGAAAGATAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (74-277)

• DprA winged helix domain (DprA_WH) (300-353)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Legionella pneumophila strain ERS1305867	98.338	100	0.983
dprA	Vibrio cholerae strain A1552	43.164	100	0.446
dprA	Vibrio campbellii strain DS40M4	44.722	99.723	0.446
dprA	Glaesserella parasuis strain SC1401	39.947	100	0.418
dprA	Haemophilus influenzae Rd KW20	46.735	80.609	0.377