Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   C4X49_RS14400 Genome accession   NZ_CP028138
Coordinates   2956099..2956773 (-) Length   224 a.a.
NCBI ID   WP_004746055.1    Uniprot ID   K7XJ84
Organism   Acinetobacter baumannii strain NCIMB 8209     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 2951099..2961773
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C4X49_RS14375 (C4X49_14365) - 2951514..2952398 (+) 885 WP_032036149.1 LysR family transcriptional regulator -
  C4X49_RS14385 (C4X49_14375) - 2952701..2953888 (+) 1188 WP_032036147.1 ammonium transporter -
  C4X49_RS14390 (C4X49_14380) - 2954040..2954738 (+) 699 WP_031978550.1 phosphatase PAP2 family protein -
  C4X49_RS14395 (C4X49_14385) - 2954739..2956073 (-) 1335 WP_109267654.1 ATP-binding protein -
  C4X49_RS14400 (C4X49_14390) ciaR 2956099..2956773 (-) 675 WP_004746055.1 DNA-binding response regulator PmrA Regulator
  C4X49_RS14405 (C4X49_14395) - 2956788..2958437 (-) 1650 WP_031945667.1 phosphoethanolamine transferase -
  C4X49_RS14410 (C4X49_14400) - 2958620..2959951 (-) 1332 WP_109267647.1 DcaP family trimeric outer membrane transporter -
  C4X49_RS14415 (C4X49_14405) - 2960497..2961744 (-) 1248 WP_109267646.1 MFS transporter -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25534.40 Da        Isoelectric Point: 5.6117

>NTDB_id=238265 C4X49_RS14400 WP_004746055.1 2956099..2956773(-) (ciaR) [Acinetobacter baumannii strain NCIMB 8209]
MTKILMIEDDFMIAESTTTLLQYHQFEVEWVNNGLDGLAQLAKNKFDLILLDLGLPMMDGMQVLKQIRQRAATPVLIISA
RDQLQNRVDGLNLGADDYLIKPYEFDELLARIHALLRRSGVEAQLASQDQLLQSGDLVLNVEQHIATFKGQRIDLSNREW
AILIPLMSHPNKIFSKANLEDKLYDFDSDVTSNTIEVYVHHLRAKLGKDFIRTIRGLGYRLGQS

Nucleotide


Download         Length: 675 bp        

>NTDB_id=238265 C4X49_RS14400 WP_004746055.1 2956099..2956773(-) (ciaR) [Acinetobacter baumannii strain NCIMB 8209]
ATGACAAAAATCTTGATGATTGAAGATGATTTTATGATTGCAGAATCAACGACTACGTTGCTGCAATATCATCAATTTGA
GGTGGAATGGGTCAATAACGGTTTAGATGGTTTGGCCCAATTGGCAAAGAATAAGTTTGATCTCATTCTTTTAGATTTGG
GCTTGCCTATGATGGATGGGATGCAGGTTTTAAAGCAAATCCGTCAAAGAGCAGCAACGCCTGTCTTAATTATCTCTGCG
CGTGACCAACTGCAAAACCGTGTTGATGGTTTGAATTTGGGAGCAGATGATTACTTAATTAAGCCATATGAGTTTGATGA
GTTACTTGCTCGCATTCACGCATTATTGCGCCGTAGTGGAGTAGAGGCTCAACTTGCTAGCCAAGATCAACTATTACAAA
GTGGTGATCTGGTTTTAAATGTTGAACAGCATATTGCAACATTTAAAGGGCAACGTATTGATTTATCGAATCGTGAGTGG
GCAATCTTGATTCCGCTTATGAGTCATCCAAATAAAATTTTCTCAAAAGCTAATTTGGAAGATAAGTTATATGACTTTGA
TAGTGATGTGACCAGCAACACGATTGAGGTATATGTCCATCATTTAAGGGCTAAGTTGGGTAAAGACTTTATTCGAACTA
TCCGAGGACTGGGTTACCGTTTAGGGCAATCATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(150-221)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB K7XJ84

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.496

100

0.388
  ciaR Streptococcus pneumoniae D39

38.496

100

0.388
  ciaR Streptococcus pneumoniae R6

38.496

100

0.388
  ciaR Streptococcus pneumoniae TIGR4

38.496

100

0.388
  ciaR Streptococcus mutans UA159

37.445

100

0.379
  micA Streptococcus pneumoniae Cp1015

36.842

100

0.375