Detailed information    

insolico Bioinformatically predicted

Overview

Name   coiA   Type   Machinery gene
Locus tag   M6_RS05565 Genome accession   NC_006086
Coordinates   1110585..1111547 (-) Length   320 a.a.
NCBI ID   WP_002983995.1    Uniprot ID   -
Organism   Streptococcus pyogenes MGAS10394     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1105585..1116547
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M6_RS05550 (M6_Spy1109) - 1106422..1107129 (-) 708 WP_011017939.1 O-methyltransferase -
  M6_RS05555 (M6_Spy1110) - 1107195..1108391 (-) 1197 WP_002995765.1 L-lactate MFS transporter -
  M6_RS05560 (M6_Spy1111) pepF 1108767..1110572 (-) 1806 WP_002995768.1 oligoendopeptidase F Regulator
  M6_RS05565 (M6_Spy1112) coiA 1110585..1111547 (-) 963 WP_002983995.1 competence protein CoiA Machinery gene
  M6_RS05570 (M6_Spy1113) - 1111843..1112559 (-) 717 WP_011184662.1 pseudouridine synthase -
  M6_RS05575 (M6_Spy1114) nagB 1112678..1113382 (-) 705 WP_021340443.1 glucosamine-6-phosphate deaminase -
  M6_RS05580 (M6_Spy1115) queA 1113584..1114612 (+) 1029 WP_011184664.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
  M6_RS05585 (M6_Spy1116) - 1114619..1115839 (+) 1221 WP_011184665.1 DUF3114 domain-containing protein -
  M6_RS05590 (M6_Spy1117) - 1115953..1116543 (-) 591 WP_011184666.1 serine hydrolase -

Sequence

Protein


Download         Length: 320 a.a.        Molecular weight: 37801.25 Da        Isoelectric Point: 10.2848

>NTDB_id=23796 M6_RS05565 WP_002983995.1 1110585..1111547(-) (coiA) [Streptococcus pyogenes MGAS10394]
MTKILTALDGKNQLISLVTQPISTKPPFRCPACKSPVRLRQGTIRRPHFAHVQLAHCQFQAENESEEHLTLKAKLYTSLV
RTEAVCIEKYLPELQQIADLWVNDKLALEIQCSPLPVERLKKRTKAYQEKGYPVRWLLGRKLWLNTHLTALQKQFLYFSS
SLGFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLDHNIMEMFRLPYQQEILYSYQKKMTVNLSKRIQRALLARHP
KWLRRQEKAYLSGYNLLMLTTDAFYPQWRPVQSSSGFCQIKGNLRPYYESFKVYYKKEKDKKVQTLFSPKYYVKMDSNRK

Nucleotide


Download         Length: 963 bp        

>NTDB_id=23796 M6_RS05565 WP_002983995.1 1110585..1111547(-) (coiA) [Streptococcus pyogenes MGAS10394]
GTGACAAAAATATTAACCGCTTTAGATGGTAAGAATCAGCTCATTTCGCTAGTAACTCAGCCTATTTCAACGAAACCGCC
TTTTCGTTGCCCAGCTTGCAAATCTCCTGTTCGCTTGCGTCAGGGGACAATTAGACGACCTCATTTTGCCCATGTACAAC
TAGCTCATTGTCAATTCCAAGCAGAAAATGAATCTGAGGAACATTTGACGTTGAAGGCAAAACTTTACACCAGTTTAGTC
CGAACAGAAGCTGTCTGTATTGAAAAATATCTTCCTGAGCTGCAACAGATAGCAGACCTTTGGGTGAATGATAAGTTAGC
CTTAGAAATTCAGTGCAGTCCCTTGCCAGTTGAGCGTCTAAAGAAACGCACCAAAGCCTATCAAGAAAAGGGGTATCCGG
TACGATGGTTACTGGGAAGAAAATTGTGGCTTAACACTCACTTAACTGCTTTGCAAAAACAGTTTCTTTACTTTTCATCT
AGTTTGGGCTTTCATTTGTGGGAGCTGGATGCAGCTGCAAATCTGCTACGTCTCAAATATTTAATCCATGAAGACTTATT
TGGTAAGGTAAGTTACCTAACCAAAACCATTTCTTTAGACCATAATATTATGGAAATGTTTCGGTTACCCTATCAGCAAG
AAATCCTTTATTCTTATCAGAAAAAAATGACTGTGAACCTATCTAAAAGAATACAAAGAGCTCTTTTAGCTAGACACCCG
AAATGGCTACGACGACAAGAAAAGGCTTACTTATCAGGCTATAATTTACTTATGTTAACAACTGATGCTTTTTATCCTCA
ATGGAGACCAGTTCAATCTTCCAGCGGTTTTTGTCAAATTAAAGGAAATCTTCGCCCTTATTATGAAAGTTTTAAAGTCT
ATTACAAAAAAGAAAAGGATAAGAAGGTGCAAACGCTTTTTTCACCAAAATATTATGTTAAAATGGATAGTAATAGAAAA
TAA

Domains

Predicted by InterProScan.

Competence protein CoiA-like family (CoiA_nuc)

(19-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  coiA Streptococcus mitis NCTC 12261

42.903

96.875

0.416
  coiA Streptococcus pneumoniae Rx1

41.613

96.875

0.403
  coiA Streptococcus pneumoniae D39

41.613

96.875

0.403
  coiA Streptococcus pneumoniae R6

41.613

96.875

0.403
  coiA Streptococcus pneumoniae TIGR4

41.613

96.875

0.403
  coiA Lactococcus lactis subsp. cremoris KW2

39.329

100

0.403

Multiple sequence alignment