Detailed information NTG0237855

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: BG910_RS07495
• Genome accession: NZ_CP022278
• Coordinates: 1520170..1521033 (+)
• Length: 287 a.a.
• NCBI ID: WP_089036304.1
• Uniprot ID: A0A220S2H3
• Organism: Neisseria chenwenguii strain 10023
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1515170..1526033

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BG910_RS07480 (BG910_07470)	rfaQ	1515595..1516665 (-)	1071	WP_089036301.1	putative lipopolysaccharide heptosyltransferase III	-
BG910_RS07485 (BG910_07475)	pilF	1517177..1518856 (+)	1680	WP_089036302.1	type IV-A pilus assembly ATPase PilB	Machinery gene
BG910_RS07490 (BG910_07480)	pilG	1518927..1520168 (+)	1242	WP_089036303.1	type II secretion system F family protein	Machinery gene
BG910_RS07495 (BG910_07485)	pilD	1520170..1521033 (+)	864	WP_089036304.1	A24 family peptidase	Machinery gene
BG910_RS07500 (BG910_07490)	coaE	1521035..1521649 (+)	615	WP_089036305.1	dephospho-CoA kinase	-
BG910_RS07505 (BG910_07495)	yacG	1521663..1521848 (+)	186	WP_089036306.1	DNA gyrase inhibitor YacG	-
BG910_RS12565	-	1522133..1523623 (+)	1491	WP_198344769.1	hypothetical protein	-
BG910_RS07520 (BG910_07510)	-	1523653..1523985 (+)	333	WP_157694050.1	GtrA family protein	-
BG910_RS07525 (BG910_07515)	-	1523993..1524931 (+)	939	WP_089036309.1	glycosyltransferase family 2 protein	-
BG910_RS07530 (BG910_07520)	-	1524922..1525635 (+)	714	WP_089036310.1	class I SAM-dependent methyltransferase	-

Sequence

Protein

• Length: 287 a.a.
• Molecular weight: 31657.63 Da
• Isoelectric Point: 8.0145

>NTDB_id=237855 BG910_RS07495 WP_089036304.1 1520170..1521033(+) (pilD) [Neisseria chenwenguii strain 10023]
MAEYFNELAAFAIPLAAVFGLLVGSFLNVVIYRVPVMMERDWTRFAKEHLHLDLTEEEKQPFNLAKPDSRCPKCYSPVKA
WQNIPIVSYILLGGKCGTCKTPISKRYPLIELLTGILFAAVTWQYGWTWITLGGLVLTAILVALTFIDADTQYLPDQLTL
PLVWLGLLFNLNGAFAPLHSAVLGAVCGYMSLWLIANLYRLLRNQEGMGMGDFKLLAALGAWLGVGALPVLILMASVIGL
TGAVVMKVAKDQQFAFGPSLAIAGWVMFIANEPVSRLVQWWLTKSGF

Nucleotide

• Length: 864 bp

>NTDB_id=237855 BG910_RS07495 WP_089036304.1 1520170..1521033(+) (pilD) [Neisseria chenwenguii strain 10023]
ATGGCAGAATATTTCAACGAGTTGGCTGCTTTTGCCATTCCTTTGGCAGCCGTTTTCGGTTTGCTGGTCGGCAGTTTTCT
GAATGTTGTGATTTACCGCGTTCCCGTGATGATGGAGCGCGATTGGACGCGGTTTGCCAAAGAGCATTTGCATTTGGACC
TGACCGAAGAAGAAAAACAGCCGTTTAATCTGGCCAAACCCGATTCCCGCTGCCCGAAGTGCTATTCGCCCGTCAAGGCT
TGGCAAAATATTCCCATCGTCAGCTATATTTTGCTTGGCGGGAAATGCGGCACCTGTAAAACGCCCATCAGCAAGCGTTA
TCCTTTAATCGAGCTTCTGACTGGTATTTTATTCGCCGCGGTTACATGGCAATACGGCTGGACATGGATTACATTGGGCG
GGTTGGTATTAACCGCCATACTGGTGGCGCTGACCTTTATCGACGCCGATACCCAGTATCTGCCCGACCAGCTGACTCTG
CCGCTGGTGTGGTTGGGGCTGCTGTTCAATCTTAACGGCGCGTTTGCACCTTTGCACTCTGCCGTATTGGGCGCCGTTTG
CGGTTATATGAGCTTGTGGCTGATCGCCAATCTTTACCGCCTGCTCCGCAACCAAGAAGGCATGGGCATGGGCGATTTCA
AACTCTTGGCTGCCTTGGGCGCATGGCTGGGTGTGGGCGCTTTGCCGGTGTTGATTCTGATGGCTTCCGTTATCGGATTA
ACCGGCGCCGTGGTCATGAAAGTCGCTAAAGACCAACAGTTCGCCTTCGGCCCCAGTCTTGCGATTGCCGGTTGGGTGAT
GTTTATCGCCAACGAGCCGGTTTCCCGTTTGGTACAATGGTGGCTGACAAAATCAGGATTCTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (18-125)

• Type IV leader peptidase family (Peptidase_A24) (135-240)

3D structure

• AlphaFold DB: A0A220S2H3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	70.397	96.516	0.679
pilD	Acinetobacter nosocomialis M2	46.237	97.213	0.449
pilD	Acinetobacter baumannii D1279779	46.237	97.213	0.449
pilD	Vibrio cholerae strain A1552	46.739	96.167	0.449
pilD	Vibrio campbellii strain DS40M4	43.902	100	0.439