Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   M6_RS00905 Genome accession   NC_006086
Coordinates   145120..145548 (+) Length   142 a.a.
NCBI ID   WP_011184089.1    Uniprot ID   -
Organism   Streptococcus pyogenes MGAS10394     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 140120..150548
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M6_RS00885 (M6_Spy0133) - 142451..142816 (+) 366 WP_002986560.1 DUF1033 family protein -
  M6_RS00890 (M6_Spy0134) comGA 142909..143847 (+) 939 WP_002986557.1 competence type IV pilus ATPase ComGA Machinery gene
  M6_RS00895 (M6_Spy0135) comGB 143783..144817 (+) 1035 WP_011184088.1 competence type IV pilus assembly protein ComGB Machinery gene
  M6_RS00900 (M6_Spy0136) comGC 144819..145145 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  M6_RS00905 (M6_Spy0137) comGD 145120..145548 (+) 429 WP_011184089.1 competence type IV pilus minor pilin ComGD Machinery gene
  M6_RS00910 (M6_Spy0138) comGE 145505..145789 (+) 285 WP_027968839.1 competence type IV pilus minor pilin ComGE Machinery gene
  M6_RS00915 (M6_Spy0139) comGF 145782..146216 (+) 435 WP_002986542.1 competence type IV pilus minor pilin ComGF Machinery gene
  M6_RS00920 (M6_Spy0140) comGG 146200..146526 (+) 327 WP_002986539.1 competence type IV pilus minor pilin ComGG -
  M6_RS00925 (M6_Spy0141) comGH 146624..147577 (+) 954 WP_021340467.1 class I SAM-dependent methyltransferase Machinery gene
  M6_RS00930 (M6_Spy0142) - 147636..148832 (+) 1197 WP_002986533.1 acetate kinase -
  M6_RS00935 (M6_Spy0143) - 149019..149327 (+) 309 WP_011017251.1 hypothetical protein -
  M6_RS00940 (M6_Spy0144) proC 149410..150180 (-) 771 WP_011184092.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 142 a.a.        Molecular weight: 16337.07 Da        Isoelectric Point: 10.3481

>NTDB_id=23751 M6_RS00905 WP_011184089.1 145120..145548(+) (comGD) [Streptococcus pyogenes MGAS10394]
MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEHLFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTE
GNNLTVPKSITVNHPYRLVIDQMGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP

Nucleotide


Download         Length: 429 bp        

>NTDB_id=23751 M6_RS00905 WP_011184089.1 145120..145548(+) (comGD) [Streptococcus pyogenes MGAS10394]
ATGAAAAAGCCCGTCTTAGCAATTAAAGCTTTTACTTTGCTTGAAACTTTACTAAGTTTGTCAGTGATGAGTTTCATTAT
ATTGGGATTGTCTGTACCAGTGACAAAAAGCTATCAAAAAGTAGAAGAGCATCTGTTTTTTAGCCATTTTGAACATTTGT
ATCGACATCAGCAAAAGTTAGCCATATTACAGCAAAAACAGCGCGTCTTGGATATTTCTTCAACAAAAATTGTTACAGAA
GGTAATAACCTAACAGTTCCTAAATCAATAACAGTGAATCATCCTTATCGGTTAGTTATTGATCAGATGGGAGGCAACCA
TTCCTTAGCTAAAATTATTTTTGACATGACTGATCGACGCTTTAAATACCAATTTTATCTAGGGAGTGGGAATTATCAAA
AAACAAGTCAAAGCTTACATAGCCCTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus mutans UA159

45.736

90.845

0.415
  comGD Streptococcus mutans UA140

45.736

90.845

0.415
  comGD/cglD Streptococcus mitis NCTC 12261

40.441

95.775

0.387
  comGD Streptococcus gordonii str. Challis substr. CH1

40.458

92.254

0.373
  comGD/cglD Streptococcus mitis SK321

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae Rx1

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae D39

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae R6

39.695

92.254

0.366

Multiple sequence alignment