Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   CEP76_RS07295 Genome accession   NZ_CP022037
Coordinates   1494849..1496042 (-) Length   397 a.a.
NCBI ID   WP_010945037.1    Uniprot ID   Q7VM72
Organism   [Haemophilus] ducreyi strain FDAARGOS_297     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1489849..1501042
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CEP76_RS07270 (CEP76_07275) lptE 1491769..1492266 (+) 498 WP_010945042.1 LPS assembly lipoprotein LptE -
  CEP76_RS07275 (CEP76_07280) holA 1492272..1493297 (+) 1026 WP_010945041.1 DNA polymerase III subunit delta -
  CEP76_RS07280 (CEP76_07285) yacG 1493331..1493519 (-) 189 WP_010945040.1 DNA gyrase inhibitor YacG -
  CEP76_RS07285 (CEP76_07290) coaE 1493522..1494139 (-) 618 WP_010945039.1 dephospho-CoA kinase -
  CEP76_RS07290 (CEP76_07295) - 1494157..1494849 (-) 693 WP_041603480.1 prepilin peptidase -
  CEP76_RS07295 (CEP76_07300) pilC 1494849..1496042 (-) 1194 WP_010945037.1 type II secretion system F family protein Machinery gene
  CEP76_RS07300 (CEP76_07305) pilB 1496026..1497420 (-) 1395 WP_010945036.1 GspE/PulE family protein Machinery gene
  CEP76_RS07305 (CEP76_07310) pilA 1497432..1497881 (-) 450 WP_010945035.1 prepilin peptidase-dependent pilin Machinery gene
  CEP76_RS07310 (CEP76_07315) radA 1498075..1499454 (+) 1380 WP_010945034.1 DNA repair protein RadA -
  CEP76_RS07315 (CEP76_07320) - 1499521..1499736 (-) 216 WP_010945033.1 YgjV family protein -
  CEP76_RS07320 (CEP76_07325) - 1499858..1500343 (-) 486 WP_010945031.1 dihydrofolate reductase -

Sequence

Protein


Download         Length: 397 a.a.        Molecular weight: 45721.33 Da        Isoelectric Point: 10.1310

>NTDB_id=236055 CEP76_RS07295 WP_010945037.1 1494849..1496042(-) (pilC) [[Haemophilus] ducreyi strain FDAARGOS_297]
MLKIYEFHWRAFNRFNQRQKGKSLAKSHDELEQRLLAKGYSNIHIQRNFILVRKPKSEQITQLINQLAMLLNASVPLKQS
LVMVLENVHNIKLYLWLSEIIMLLEAGHAFSASLTKMNVYLTKQEIQLIQMGEQSGRLAIMLDNIAQVRNQSQKLANKVK
KIMFYPAIILAVSISVLIGLLLFIVPQFEDLYRNKDQSLPFITQLLFQLSNFLQQYAFILFIGGLFSGIVSYFLAKKWLF
WRTLRSRLLNHMPGFQQIIKDARIIFFSQNLALMLNAHIHLDATLKAFLSEHRQDPVLHQEILSILSLLKQGYKFSEGLN
PTVFTSQVVQMMAIGEQSGNLAKMCMYISQLYQQKLDYQIDLFAQLLEPVLMVVIGIIVGTILIGIYLPIFDMGALV

Nucleotide


Download         Length: 1194 bp        

>NTDB_id=236055 CEP76_RS07295 WP_010945037.1 1494849..1496042(-) (pilC) [[Haemophilus] ducreyi strain FDAARGOS_297]
ATGCTGAAAATATATGAATTTCATTGGCGGGCTTTTAATCGTTTTAATCAACGGCAAAAAGGTAAATCTCTGGCCAAAAG
TCACGATGAATTAGAACAACGGCTATTAGCTAAAGGCTATTCAAATATCCATATTCAACGTAATTTTATTTTAGTTAGGA
AACCAAAAAGCGAACAAATCACTCAATTAATTAATCAGTTAGCTATGTTATTGAATGCCTCGGTTCCATTAAAACAATCG
CTGGTGATGGTATTAGAAAACGTACATAATATTAAATTATATTTATGGCTATCTGAAATTATTATGCTGTTAGAAGCGGG
GCATGCTTTTTCAGCCAGTCTCACTAAAATGAACGTTTATTTGACTAAGCAAGAAATTCAGTTAATTCAGATGGGAGAAC
AGAGTGGGCGTTTAGCCATTATGCTAGATAACATTGCACAAGTACGTAATCAATCACAGAAATTAGCTAATAAAGTAAAG
AAAATTATGTTTTATCCGGCGATTATTTTAGCCGTATCAATTAGTGTATTAATTGGATTGTTATTATTTATTGTGCCTCA
ATTTGAAGATCTTTATCGTAACAAAGATCAGTCACTGCCTTTTATTACCCAATTATTATTTCAGTTATCGAATTTTCTTC
AACAATATGCATTTATTTTATTCATCGGCGGCCTATTTAGCGGTATTGTTAGCTATTTTTTAGCGAAAAAGTGGCTTTTT
TGGCGTACCTTAAGATCGCGTTTATTAAATCATATGCCAGGGTTTCAGCAAATTATTAAAGATGCTCGAATTATTTTCTT
TAGTCAAAATCTTGCGTTAATGCTTAATGCACATATTCATTTAGATGCAACGTTAAAAGCATTTTTATCAGAACATCGCC
AAGATCCGGTATTACATCAGGAGATTTTGAGTATATTAAGTTTATTAAAGCAAGGTTATAAATTCTCTGAGGGGCTTAAT
CCAACCGTATTTACTAGCCAAGTAGTACAAATGATGGCAATTGGCGAACAAAGTGGTAATTTGGCTAAAATGTGTATGTA
TATTAGTCAACTGTATCAGCAAAAACTGGATTACCAAATTGATTTGTTTGCTCAATTACTTGAACCGGTTTTAATGGTAG
TGATTGGCATTATTGTGGGGACGATTTTGATTGGGATTTATTTGCCTATTTTTGATATGGGAGCATTGGTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(64-186)

Type II secretion system (T2SS), protein F (T2SSF)

(267-389)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q7VM72

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Glaesserella parasuis strain SC1401

51.637

100

0.516
  pilC Haemophilus influenzae Rd KW20

40.75

100

0.411
  pilC Haemophilus influenzae 86-028NP

40.25

100

0.406

Multiple sequence alignment