Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   AAF93_RS26335 Genome accession   NZ_CP027472
Coordinates   4867520..4868152 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2014C-3050     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4862520..4873152
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAF93_RS26310 yhfG 4862652..4862819 (+) 168 WP_000736860.1 YhfG family protein -
  AAF93_RS26315 fic 4862809..4863411 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  AAF93_RS26320 pabA 4863443..4864006 (+) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  AAF93_RS26325 argD 4864092..4865312 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  AAF93_RS26330 yhfK 4865379..4867469 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  AAF93_RS26335 crp 4867520..4868152 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  AAF93_RS26345 yhfA 4868454..4868858 (+) 405 WP_001148908.1 OsmC family protein -
  AAF93_RS26350 prkB 4868913..4869782 (-) 870 WP_001274680.1 phosphoribulokinase -
  AAF93_RS26355 yheU 4869836..4870054 (-) 219 WP_000907085.1 YheU family protein -
  AAF93_RS26360 yheT 4870048..4871070 (-) 1023 WP_000057356.1 hydrolase -
  AAF93_RS26365 yheS 4871070..4872983 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=234839 AAF93_RS26335 WP_000242755.1 4867520..4868152(-) (crp) [Escherichia coli strain 2014C-3050]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=234839 AAF93_RS26335 WP_000242755.1 4867520..4868152(-) (crp) [Escherichia coli strain 2014C-3050]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTTTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATTGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment