Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C6W79_RS11500 Genome accession   NZ_CP027457
Coordinates   2352871..2353503 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 88-3493     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2347871..2358503
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6W79_RS11475 yhfG 2348003..2348170 (+) 168 WP_000736862.1 YhfG family protein -
  C6W79_RS11480 fic 2348160..2348762 (+) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  C6W79_RS11485 pabA 2348794..2349357 (+) 564 WP_000601848.1 aminodeoxychorismate synthase component 2 -
  C6W79_RS11490 argD 2349443..2350663 (+) 1221 WP_001613951.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C6W79_RS11495 yhfK 2350730..2352820 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  C6W79_RS11500 crp 2352871..2353503 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C6W79_RS11510 yhfA 2353805..2354209 (+) 405 WP_001148908.1 OsmC family protein -
  C6W79_RS11515 prkB 2354264..2355133 (-) 870 WP_001274680.1 phosphoribulokinase -
  C6W79_RS11520 yheU 2355187..2355405 (-) 219 WP_000907085.1 YheU family protein -
  C6W79_RS11525 yheT 2355399..2356421 (-) 1023 WP_000057392.1 hydrolase -
  C6W79_RS11530 yheS 2356421..2358334 (-) 1914 WP_001613950.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=234495 C6W79_RS11500 WP_000242755.1 2352871..2353503(-) (crp) [Escherichia coli strain 88-3493]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=234495 C6W79_RS11500 WP_000242755.1 2352871..2353503(-) (crp) [Escherichia coli strain 88-3493]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTCAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment