Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C6W71_RS12800 Genome accession   NZ_CP027452
Coordinates   2493371..2494003 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2014C-3338     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2488371..2499003
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6W71_RS12775 yhfG 2488503..2488670 (+) 168 WP_000736860.1 YhfG family protein -
  C6W71_RS12780 fic 2488660..2489262 (+) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  C6W71_RS12785 pabA 2489294..2489857 (+) 564 WP_042103625.1 aminodeoxychorismate synthase component 2 -
  C6W71_RS12790 argD 2489943..2491163 (+) 1221 WP_001525813.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C6W71_RS12795 yhfK 2491230..2493320 (-) 2091 WP_001571992.1 YccS/YhfK family putative transporter -
  C6W71_RS12800 crp 2493371..2494003 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C6W71_RS12810 yhfA 2494305..2494709 (+) 405 WP_001148908.1 OsmC family protein -
  C6W71_RS12815 prkB 2494764..2495633 (-) 870 WP_001274680.1 phosphoribulokinase -
  C6W71_RS12820 yheU 2495687..2495905 (-) 219 WP_000907085.1 YheU family protein -
  C6W71_RS12825 yheT 2495899..2496921 (-) 1023 WP_042103628.1 hydrolase -
  C6W71_RS12830 yheS 2496921..2498834 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=234340 C6W71_RS12800 WP_000242755.1 2493371..2494003(-) (crp) [Escherichia coli strain 2014C-3338]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=234340 C6W71_RS12800 WP_000242755.1 2493371..2494003(-) (crp) [Escherichia coli strain 2014C-3338]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment