Detailed information NTG0234179

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: BB159_RS04570
• Genome accession: NZ_CP021868
• Coordinates: 847573..849810 (+)
• Length: 745 a.a.
• NCBI ID: WP_000939901.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain SG-M8
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 842573..854810

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BB159_RS04545 (BB159_04545)	-	843167..844753 (+)	1587	WP_000673089.1	DEAD/DEAH box helicase	-
BB159_RS04550 (BB159_04550)	-	844938..845204 (-)	267	WP_000598736.1	GIY-YIG nuclease family protein	-
BB159_RS04555 (BB159_04555)	-	845197..845961 (-)	765	WP_000567423.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
BB159_RS04560 (BB159_04560)	-	846096..846836 (+)	741	WP_000500220.1	lysophospholipid acyltransferase family protein	-
BB159_RS04565 (BB159_04565)	-	846936..847589 (+)	654	WP_000461744.1	helix-hairpin-helix domain-containing protein	-
BB159_RS04570 (BB159_04570)	comEC/celB	847573..849810 (+)	2238	WP_000939901.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
BB159_RS04575 (BB159_04575)	-	849936..850745 (+)	810	WP_000153219.1	Cof-type HAD-IIB family hydrolase	-
BB159_RS04580 (BB159_04580)	-	850756..851700 (+)	945	WP_000200830.1	LacI family DNA-binding transcriptional regulator	-
BB159_RS04585 (BB159_04585)	-	851759..852751 (-)	993	WP_000800995.1	alpha/beta hydrolase fold domain-containing protein	-
BB159_RS04590 (BB159_04590)	-	852927..853655 (+)	729	WP_000468966.1	methyltransferase domain-containing protein	-
BB159_RS04595 (BB159_04595)	holA	853709..854746 (+)	1038	WP_000560292.1	DNA polymerase III subunit delta	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 85415.23 Da
• Isoelectric Point: 9.7742

>NTDB_id=234179 BB159_RS04570 WP_000939901.1 847573..849810(+) (comEC/celB) [Streptococcus agalactiae strain SG-M8]
MLQLTKYFPLKPIYLALLVFQIYLLVFSWTMLGCAFLLFSFIFLIYQYDRETIFKTIAIVIFFLFYFLWQNHNMNVQYQR
VPNHISQIKVRIDTISINGDVLSFQADASGNTYQAFYTLKNKSEKDYFQNLDNNIMIIADIKLEEAEERRHFNGFDYRQY
LKRHGIYRIAKVTKIKQIRLFQHRSFFALMSKWRRSAIVISQTFPNPMRHYMSGLLFGYLDKTFDDMSDLYSSLGIIHLF
ALSGMQVGFFLGIFRYICLRIGLRLDHVWLLQIPFSLIYAGLTGFSISVVRALIQSLLSHSGVKKDENFALCLLICLISL
PHSLLTTGGVLSFAYAFILTMTSFDHFSSIKKVAIESLTVSVGILPILTYYFSGFQPISIILTALLSFAFDIIFLPLLTV
IFVLSPIVKLSCINSLFEILEVLLKWTGQLFPRPLIFGKPSLFLLIVMIIILGLLYDYYHSKCFRYCSLLIIFTLFFITK
NPITNEVAILDVGQGDSILVRDWLGKTILIDTGGRVRFEQPEEWKQKVNQSNAERTLIPYLKSRGISKIDDLVITHTDTD
HMGDMEVISKHFKVARLITSSGSSTNSQYVKHLSKIGVAVKSIEAGDKLAVMGSYLQVLYPWHKGDGKNNDSIVLYGHLL
GKGFLFTGDLEEEGEKQLLEAYPNLSVDILKAGHHGSKGSSSLSFLKKLSPSVVLVSAGKNNRYQHPHQETLQRFQKIKS
KIFRTDQSGTIRLTGWWKWHIQTVR

Nucleotide

• Length: 2238 bp

>NTDB_id=234179 BB159_RS04570 WP_000939901.1 847573..849810(+) (comEC/celB) [Streptococcus agalactiae strain SG-M8]
ATGTTACAATTGACTAAGTATTTTCCTCTAAAACCTATTTATTTAGCATTGTTGGTCTTCCAAATTTACTTACTAGTGTT
TTCTTGGACAATGCTTGGTTGTGCCTTTCTTTTATTTTCTTTTATTTTTCTGATTTATCAATATGATCGTGAAACTATTT
TTAAAACAATAGCAATAGTAATTTTTTTCTTATTTTATTTTTTATGGCAAAATCACAATATGAATGTCCAATATCAAAGA
GTACCGAATCATATTAGCCAGATTAAAGTGCGTATTGATACTATTTCTATCAATGGTGATGTTTTATCATTCCAGGCAGA
TGCTTCAGGTAACACTTATCAAGCTTTTTACACATTAAAAAATAAAAGTGAGAAAGATTATTTTCAAAATCTTGATAATA
ATATAATGATAATTGCAGATATCAAACTTGAAGAAGCAGAGGAGAGAAGGCATTTTAATGGCTTTGATTATCGTCAGTAT
TTAAAAAGACATGGAATTTATCGTATCGCCAAAGTGACAAAGATAAAACAGATACGCTTATTTCAACATAGGTCTTTCTT
TGCTCTTATGTCTAAGTGGCGTAGAAGTGCAATTGTTATTAGTCAAACTTTTCCAAATCCTATGCGTCACTATATGTCAG
GGCTTTTGTTTGGATATCTAGATAAGACCTTTGATGACATGTCCGATTTATATAGTAGTCTAGGTATTATACATTTATTT
GCTTTGTCAGGTATGCAAGTAGGTTTTTTTCTCGGTATTTTTCGTTATATCTGTCTACGTATTGGCTTACGTCTAGACCA
TGTTTGGTTACTTCAAATACCATTCTCGCTAATTTATGCTGGTTTAACAGGCTTTAGTATCTCAGTCGTTAGGGCACTTA
TTCAATCTTTATTATCACATAGCGGTGTCAAGAAAGATGAGAACTTTGCTCTCTGCTTGTTAATTTGTCTTATCTCCCTC
CCCCACTCACTTTTGACTACGGGAGGAGTTCTTAGCTTTGCTTATGCTTTTATACTTACGATGACCTCCTTTGATCATTT
TTCGAGTATAAAAAAAGTAGCTATCGAATCTTTGACAGTCTCTGTAGGAATTCTTCCCATACTAACCTACTATTTTTCGG
GTTTTCAACCAATATCAATTATATTAACAGCACTTTTATCTTTTGCATTTGATATTATATTTTTGCCTTTATTAACTGTT
ATATTTGTCTTATCGCCTATCGTTAAATTAAGTTGTATTAATAGTTTGTTTGAAATCCTAGAAGTGTTATTAAAATGGAC
TGGGCAACTGTTTCCAAGGCCACTTATTTTTGGAAAGCCCAGCCTTTTTCTTTTAATAGTCATGATTATAATTTTGGGAT
TACTTTATGATTATTATCATTCTAAATGTTTTCGTTATTGCTCCCTTCTTATTATCTTTACCTTGTTTTTTATCACTAAG
AATCCAATTACTAACGAGGTTGCGATTTTAGATGTTGGACAGGGAGATAGTATTTTAGTGAGGGATTGGTTAGGAAAAAC
AATTTTAATTGATACTGGGGGAAGGGTGAGATTTGAACAGCCTGAAGAATGGAAACAAAAAGTAAATCAGTCTAATGCTG
AGAGAACGCTCATTCCTTACTTGAAAAGCAGAGGTATTAGCAAGATAGATGATTTAGTGATAACTCATACCGATACAGAT
CATATGGGGGATATGGAAGTTATCTCAAAGCATTTTAAAGTTGCACGTTTGATTACAAGTTCAGGTTCTTCAACGAATTC
GCAGTACGTTAAGCATTTATCAAAGATAGGTGTAGCGGTAAAATCTATAGAAGCCGGTGATAAACTTGCTGTCATGGGAA
GTTATTTACAAGTACTTTACCCATGGCACAAGGGTGATGGAAAAAATAATGATTCAATTGTTTTATATGGACATTTATTA
GGAAAAGGCTTCTTATTTACCGGTGATTTGGAGGAAGAGGGAGAAAAGCAGTTATTAGAAGCTTATCCTAATTTATCAGT
AGATATCCTTAAAGCAGGACATCATGGTTCTAAGGGCTCATCAAGTCTATCCTTTCTGAAAAAGTTGTCTCCTAGTGTGG
TTCTAGTTTCAGCTGGTAAAAATAATCGTTACCAGCATCCTCATCAAGAGACTTTACAAAGGTTCCAAAAGATTAAAAGC
AAGATTTTCCGAACGGATCAATCAGGTACAATTAGGCTAACAGGATGGTGGAAGTGGCATATTCAGACAGTTCGTTGA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (215-458)

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-576)

• Domain of unknown function (DUF4131) (DUF4131) (27-177)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	48.267	100	0.486
comEC/celB	Streptococcus mitis SK321	48.396	100	0.486
comEC/celB	Streptococcus pneumoniae TIGR4	46.925	100	0.471
comEC/celB	Streptococcus pneumoniae Rx1	46.452	100	0.466
comEC/celB	Streptococcus pneumoniae D39	46.452	100	0.466
comEC/celB	Streptococcus pneumoniae R6	46.452	100	0.466
comEC	Lactococcus lactis subsp. cremoris KW2	43.203	99.732	0.431