Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   C6N65_RS07605 Genome accession   NZ_CP027325
Coordinates   1490846..1491478 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 2013C-4830     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1485846..1496478
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C6N65_RS07580 yhfG 1485979..1486146 (+) 168 WP_000736863.1 YhfG family protein -
  C6N65_RS07585 fic 1486136..1486738 (+) 603 WP_001280650.1 putative adenosine monophosphate-protein transferase Fic -
  C6N65_RS07590 pabA 1486770..1487333 (+) 564 WP_000601849.1 aminodeoxychorismate synthase component 2 -
  C6N65_RS07595 argD 1487419..1488639 (+) 1221 WP_032207219.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  C6N65_RS07600 yhfK 1488705..1490795 (-) 2091 WP_001297515.1 YccS/YhfK family putative transporter -
  C6N65_RS07605 crp 1490846..1491478 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  C6N65_RS07615 yhfA 1491780..1492184 (+) 405 WP_001148908.1 OsmC family protein -
  C6N65_RS07620 prkB 1492239..1493108 (-) 870 WP_001274680.1 phosphoribulokinase -
  C6N65_RS07625 yheU 1493162..1493380 (-) 219 WP_000907085.1 YheU family protein -
  C6N65_RS07630 yheT 1493374..1494396 (-) 1023 WP_000057379.1 hydrolase -
  C6N65_RS07635 yheS 1494396..1496309 (-) 1914 WP_032207216.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=232144 C6N65_RS07605 WP_000242755.1 1490846..1491478(-) (crp) [Escherichia coli strain 2013C-4830]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=232144 C6N65_RS07605 WP_000242755.1 1490846..1491478(-) (crp) [Escherichia coli strain 2013C-4830]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment