Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   SMU_RS02590 Genome accession   NC_004350
Coordinates   504962..505618 (-) Length   218 a.a.
NCBI ID   WP_002279623.1    Uniprot ID   Q8DVF1
Organism   Streptococcus mutans UA159     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 499962..510618
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMU_RS02565 (SMU.534) trpD 500396..501403 (+) 1008 WP_002262053.1 anthranilate phosphoribosyltransferase -
  SMU_RS02570 (SMU.535) trpC 501396..502163 (+) 768 WP_002262054.1 indole-3-glycerol phosphate synthase TrpC -
  SMU_RS02575 (SMU.536) - 502150..502731 (+) 582 WP_002262055.1 phosphoribosylanthranilate isomerase -
  SMU_RS02580 (SMU.537) trpB 502728..503939 (+) 1212 WP_002262056.1 tryptophan synthase subunit beta -
  SMU_RS02585 (SMU.538) trpA 503943..504725 (+) 783 WP_002262057.1 tryptophan synthase subunit alpha -
  SMU_RS02590 (SMU.539c) cclA/cilC 504962..505618 (-) 657 WP_002279623.1 prepilin peptidase Machinery gene
  SMU_RS02595 (SMU.540) dpr 505719..506246 (+) 528 WP_002262059.1 DNA starvation/stationary phase protection protein -
  SMU_RS02600 (SMU.541) - 506453..506659 (+) 207 WP_002262060.1 YqgQ family protein -
  SMU_RS02605 (SMU.542) - 506652..507623 (+) 972 WP_002262061.1 ROK family glucokinase -
  SMU_RS02610 (SMU.543) - 507633..508022 (+) 390 WP_002262062.1 rhodanese-like domain-containing protein -
  SMU_RS02615 (SMU.546) typA 508256..510100 (+) 1845 WP_002262063.1 translational GTPase TypA -
  SMU_RS02620 (SMU.547) - 510129..510383 (+) 255 WP_002262064.1 DUF3165 family protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 24845.06 Da        Isoelectric Point: 8.5763

>NTDB_id=22957 SMU_RS02590 WP_002279623.1 504962..505618(-) (cclA/cilC) [Streptococcus mutans UA159]
MKLILFFMLGASLGSFFGLVVDRYPQKSIIFPRSHCNKCYNCLTMRDLIPIFSRIINKNSCRFCGYPIPLRYSLVELLCG
LISTGFALDLLTTSQVCLLFMGVLLSLYDLQDQSYPLTLWIGFTFLLMFIYPLNLISLILFLFGIFAALKNINIGSGDFL
YLATLALSLNLQQIIWIIQIASLLGILYSLLFQKHKEPFAFVPFLFVGHLIIIFSHLI

Nucleotide


Download         Length: 657 bp        

>NTDB_id=22957 SMU_RS02590 WP_002279623.1 504962..505618(-) (cclA/cilC) [Streptococcus mutans UA159]
ATGAAACTTATTTTATTTTTTATGTTGGGAGCTTCTCTTGGCTCTTTCTTTGGCTTAGTTGTTGATCGTTACCCTCAGAA
ATCTATTATATTTCCTAGAAGCCATTGCAATAAGTGTTATAACTGCTTAACCATGAGGGATCTTATCCCAATATTTTCAC
GAATCATCAACAAAAATTCTTGTCGCTTTTGCGGTTACCCTATTCCATTGCGTTATTCTTTGGTAGAATTACTCTGCGGA
CTGATTAGCACAGGTTTTGCTCTTGATTTATTAACCACTTCACAAGTATGTTTGCTCTTCATGGGAGTTCTTTTATCTCT
TTATGATTTACAAGATCAGTCTTATCCTTTGACACTGTGGATAGGCTTTACTTTTCTCTTAATGTTTATCTATCCTCTTA
ACCTAATTAGCTTAATTCTTTTTCTATTTGGTATTTTTGCTGCCCTCAAAAATATTAATATCGGAAGCGGTGATTTCCTC
TATCTGGCTACTTTGGCACTTTCTCTTAATCTTCAGCAAATTATTTGGATTATTCAGATTGCCAGTTTATTAGGAATTCT
TTACAGCCTGCTTTTTCAAAAGCACAAAGAACCTTTTGCTTTTGTTCCTTTCTTATTCGTGGGTCACCTCATTATCATTT
TCTCTCACTTGATTTAA

Domains

Predicted by InterProScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(9-87)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DVF1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus mitis SK321

42.791

98.624

0.422
  cclA/cilC Streptococcus pneumoniae Rx1

42.254

97.706

0.413
  cclA/cilC Streptococcus pneumoniae D39

42.254

97.706

0.413
  cclA/cilC Streptococcus pneumoniae R6

42.254

97.706

0.413
  cclA/cilC Streptococcus mitis NCTC 12261

41.86

98.624

0.413
  cclA/cilC Streptococcus pneumoniae TIGR4

41.315

97.706

0.404

Multiple sequence alignment