Detailed information    

insolico Bioinformatically predicted

Overview


Name   comEA   Type   Machinery gene
Locus tag   CA925_RS04120 Genome accession   NZ_CP021266
Coordinates   907772..908089 (+) Length   105 a.a.
NCBI ID   WP_011945930.1    Uniprot ID   A0A378KB58
Organism   Legionella pneumophila subsp. pneumophila strain Knoxville     
Function   dsDNA binding (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 902772..913089
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CA925_RS04100 - 902924..904363 (+) 1440 WP_010946542.1 cation:proton antiporter -
  CA925_RS04105 nadC 904360..905202 (+) 843 WP_013101201.1 carboxylating nicotinate-nucleotide diphosphorylase -
  CA925_RS04110 - 905199..906290 (+) 1092 WP_013101202.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -
  CA925_RS04115 - 906265..907680 (+) 1416 WP_010946545.1 M20 family metallopeptidase -
  CA925_RS04120 comEA 907772..908089 (+) 318 WP_011945930.1 helix-hairpin-helix domain-containing protein Machinery gene
  CA925_RS04125 - 908285..909322 (+) 1038 WP_011213320.1 rod shape-determining protein -
  CA925_RS04130 mreC 909300..910208 (+) 909 WP_010946548.1 rod shape-determining protein MreC -
  CA925_RS04135 mreD 910205..910684 (+) 480 WP_011945932.1 rod shape-determining protein MreD -
  CA925_RS04140 - 910620..911222 (-) 603 WP_013101203.1 pseudouridine synthase -
  CA925_RS04145 - 911483..912181 (+) 699 WP_011945934.1 hypothetical protein -

Sequence


Protein


Download         Length: 105 a.a.        Molecular weight: 11747.74 Da        Isoelectric Point: 10.6194

>NTDB_id=229370 CA925_RS04120 WP_011945930.1 907772..908089(+) (comEA) [Legionella pneumophila subsp. pneumophila strain Knoxville]
MKARLIAILLSFIVIPFSSQAENEPQKTPAKQVLVKGKINLNTADVHSLTGSFKGIGKKRAEAIIAYRENHQGFKSLEEL
AEVKGIGQRFVDKNREKLKEIFVIN

Nucleotide


Download         Length: 318 bp        

>NTDB_id=229370 CA925_RS04120 WP_011945930.1 907772..908089(+) (comEA) [Legionella pneumophila subsp. pneumophila strain Knoxville]
ATGAAAGCAAGACTCATTGCTATTTTGTTGTCATTTATTGTTATCCCTTTCTCTTCTCAAGCTGAGAACGAGCCTCAAAA
AACTCCAGCTAAACAAGTCCTTGTTAAGGGCAAGATTAATCTCAATACAGCGGATGTGCATTCTTTAACAGGCTCTTTTA
AAGGGATAGGAAAAAAACGGGCTGAAGCTATTATTGCTTATAGAGAGAATCATCAAGGCTTTAAATCTCTGGAAGAGCTT
GCGGAAGTCAAGGGTATAGGGCAGCGTTTTGTAGATAAAAATAGAGAAAAACTGAAAGAAATTTTCGTTATTAATTAA

Domains


Predicted by InterproScan.

(37-98)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A378KB58

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Legionella pneumophila str. Paris

99.048

100

0.99

  comEA Legionella pneumophila strain ERS1305867

99.048

100

0.99

  comE1/comEA Haemophilus influenzae Rd KW20

35.455

100

0.371

  comEA Staphylococcus aureus N315

38.384

94.286

0.362

  comEA Staphylococcus aureus MW2

38.384

94.286

0.362


Multiple sequence alignment