Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   SAG_RS04445 Genome accession   NC_004116
Coordinates   346956..347621 (+) Length   221 a.a.
NCBI ID   WP_000128291.1    Uniprot ID   Q8E1L7
Organism   Streptococcus agalactiae 2603V/R     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 341956..352621
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAG_RS04420 (SAG0332) - 341974..342642 (+) 669 WP_000394891.1 fructose-6-phosphate aldolase -
  SAG_RS04425 (SAG0333) - 342710..343798 (+) 1089 WP_000862118.1 glycerol dehydrogenase -
  SAG_RS04430 (SAG0334) cysK 343950..344876 (-) 927 WP_000036948.1 cysteine synthase A -
  SAG_RS04435 (SAG0335) - 344967..345611 (-) 645 WP_001108147.1 YigZ family protein -
  SAG_RS04440 (SAG0336) comFA/cflA 345667..346956 (+) 1290 WP_000432961.1 DEAD/DEAH box helicase Machinery gene
  SAG_RS04445 (SAG0337) comFC/cflB 346956..347621 (+) 666 WP_000128291.1 ComF family protein Machinery gene
  SAG_RS04450 (SAG0338) hpf 347698..348252 (+) 555 WP_000599094.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25411.61 Da        Isoelectric Point: 9.3275

>NTDB_id=22861 SAG_RS04445 WP_000128291.1 346956..347621(+) (comFC/cflB) [Streptococcus agalactiae 2603V/R]
MTCLLCHEIDLSQLTFVELMLLKPKQNVICQTCKGSFEALSREMGCQTCCKQIPQKQCQDCIYWGKKGIEVNHFSLYRYN
EAMKKNFSLFKFQGDYLLKDVFTKEIKAALKKYKGYTIVPVPLSHEGYQNRQFNQVIAFLQSANIPYKNILSKKDGGKQS
ANNKEERLKQVQQFTLKNEAELGDNLLIVDDIYTTGATIAQIRKLLEEKGIKNIKSFSLAR

Nucleotide


Download         Length: 666 bp        

>NTDB_id=22861 SAG_RS04445 WP_000128291.1 346956..347621(+) (comFC/cflB) [Streptococcus agalactiae 2603V/R]
ATGACTTGTTTGTTATGTCATGAAATAGATTTATCGCAATTAACTTTTGTGGAACTTATGCTTCTAAAACCAAAGCAAAA
CGTAATTTGTCAAACGTGCAAGGGTAGTTTTGAAGCACTTAGTAGGGAGATGGGTTGCCAAACATGTTGCAAGCAAATTC
CCCAAAAACAATGTCAAGATTGTATTTATTGGGGTAAAAAAGGTATAGAGGTAAATCATTTTTCCCTTTATAGATACAAT
GAAGCAATGAAAAAAAATTTTTCTCTTTTTAAATTTCAAGGGGATTATTTGTTGAAAGATGTTTTTACAAAAGAAATAAA
AGCTGCTCTAAAAAAGTATAAGGGCTACACTATAGTGCCAGTTCCCTTGAGTCATGAAGGATACCAAAATAGGCAATTTA
ATCAAGTGATTGCTTTTCTACAATCGGCAAATATACCTTACAAAAATATTCTTTCTAAAAAAGATGGAGGTAAGCAATCG
GCTAATAATAAAGAAGAAAGACTCAAACAAGTTCAGCAATTTACATTAAAAAATGAGGCTGAGTTAGGGGACAACCTTTT
AATTGTTGATGATATTTATACAACAGGCGCAACAATAGCACAAATCAGGAAACTATTAGAAGAAAAAGGTATAAAAAATA
TAAAAAGTTTTTCATTAGCACGCTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8E1L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

42.986

100

0.43
  comFC/cflB Streptococcus pneumoniae Rx1

42.534

100

0.425
  comFC/cflB Streptococcus pneumoniae D39

42.534

100

0.425
  comFC/cflB Streptococcus pneumoniae R6

42.534

100

0.425
  comFC/cflB Streptococcus mitis SK321

41.629

100

0.416
  comFC/cflB Streptococcus mitis NCTC 12261

41.629

100

0.416

Multiple sequence alignment