Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   AM442_RS18525 Genome accession   NZ_CP026711
Coordinates   3841054..3841728 (-) Length   224 a.a.
NCBI ID   WP_000161505.1    Uniprot ID   A0A0D5YFC9
Organism   Acinetobacter baumannii strain AR_0063     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 3836054..3846728
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AM442_RS18495 (AM442_18490) - 3836329..3837213 (+) 885 WP_024437368.1 LysR family transcriptional regulator -
  AM442_RS18505 (AM442_18500) - 3837516..3838703 (+) 1188 WP_104877249.1 ammonium transporter -
  AM442_RS18510 (AM442_18505) - 3838752..3838913 (-) 162 WP_100743397.1 hypothetical protein -
  AM442_RS18515 (AM442_18510) - 3838983..3839693 (+) 711 WP_005143680.1 phosphatase PAP2 family protein -
  AM442_RS18520 (AM442_18515) - 3839694..3841028 (-) 1335 WP_104877243.1 ATP-binding protein -
  AM442_RS18525 (AM442_18520) ciaR 3841054..3841728 (-) 675 WP_000161505.1 response regulator transcription factor Regulator
  AM442_RS18530 (AM442_18525) - 3841743..3843392 (-) 1650 WP_031954446.1 phosphoethanolamine transferase -
  AM442_RS18535 (AM442_18530) - 3843574..3844878 (-) 1305 WP_000362910.1 DcaP family trimeric outer membrane transporter -
  AM442_RS18540 (AM442_18535) - 3844970..3846060 (+) 1091 WP_085940648.1 IS4-like element ISAba1 family transposase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25548.47 Da        Isoelectric Point: 5.3246

>NTDB_id=228274 AM442_RS18525 WP_000161505.1 3841054..3841728(-) (ciaR) [Acinetobacter baumannii strain AR_0063]
MTKILMIEDDFMIAESTITLLQYHQFEVEWVNNGLDGLAQLAKTKFDLILLDLGLPMMDGMQVLKQIRQRAATPVLIISA
RDQLQNRVDGLNLGADDYLIKPYEFDELLARIHALLRRSGVEAQLASQDQLLESGDLVLNVEQHIATFKGQRIDLSNREW
AILIPLMTHPNKIFSKANLEDKLYDFDSDVTSNTIEVYVHHLRAKLGKDFIRTIRGLGYRLGQS

Nucleotide


Download         Length: 675 bp        

>NTDB_id=228274 AM442_RS18525 WP_000161505.1 3841054..3841728(-) (ciaR) [Acinetobacter baumannii strain AR_0063]
ATGACAAAAATCTTGATGATTGAAGATGATTTTATGATTGCAGAATCAACGATCACGTTGCTGCAATATCATCAATTTGA
GGTGGAATGGGTCAATAACGGTTTAGATGGTTTGGCTCAATTGGCGAAGACTAAATTTGATCTTATTCTTTTGGATTTAG
GATTGCCTATGATGGATGGTATGCAAGTTTTAAAGCAGATCCGTCAAAGAGCAGCAACACCAGTATTAATTATTTCTGCT
CGAGATCAATTACAAAACCGTGTCGATGGTTTAAATTTGGGTGCAGATGATTATTTAATTAAACCTTATGAGTTTGATGA
GTTGCTTGCCCGTATTCATGCATTACTACGCCGTAGTGGAGTAGAAGCTCAACTTGCGAGTCAAGATCAACTATTAGAAA
GTGGCGATCTGGTTTTAAATGTTGAACAGCATATTGCGACGTTTAAAGGTCAACGCATTGATCTATCAAATCGTGAATGG
GCAATCTTAATTCCACTTATGACTCACCCAAATAAAATCTTTTCTAAAGCCAACTTAGAAGATAAGTTATATGATTTTGA
TAGTGATGTGACCAGTAATACTATTGAAGTATATGTTCACCATTTAAGAGCGAAGCTGGGTAAAGATTTTATCCGAACCA
TCCGAGGACTGGGCTACCGTTTGGGGCAATCATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(150-221)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 9OF3
  PDB 9OF4
  PDB 9OF5
  PDB 9OF6
  PDB 9OF7
  PDB 9OF8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.496

100

0.388
  ciaR Streptococcus pneumoniae D39

38.496

100

0.388
  ciaR Streptococcus pneumoniae R6

38.496

100

0.388
  ciaR Streptococcus pneumoniae TIGR4

38.496

100

0.388
  ciaR Streptococcus mutans UA159

37.445

100

0.379
  micA Streptococcus pneumoniae Cp1015

35.965

100

0.366

Multiple sequence alignment