Detailed information NTG0022797

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: SPYM3_RS05625
• Genome accession: NC_004070
• Coordinates: 1106788..1107750 (-)
• Length: 320 a.a.
• NCBI ID: WP_011054653.1
• Uniprot ID: A0A0H2UV79
• Organism: Streptococcus pyogenes MGAS315
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1101788..1112750

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPYM3_RS05610 (SpyM3_1060)	-	1102625..1103332 (-)	708	WP_002984000.1	O-methyltransferase	-
SPYM3_RS05615 (SpyM3_1061)	-	1103398..1104594 (-)	1197	WP_011054651.1	L-lactate MFS transporter	-
SPYM3_RS05620 (SpyM3_1062)	pepF	1104970..1106775 (-)	1806	WP_011054652.1	oligoendopeptidase F	Regulator
SPYM3_RS05625 (SpyM3_1063)	coiA	1106788..1107750 (-)	963	WP_011054653.1	competence protein CoiA	Machinery gene
SPYM3_RS05630 (SpyM3_1064)	-	1108047..1108763 (-)	717	WP_011106718.1	pseudouridine synthase	-
SPYM3_RS05635 (SpyM3_1065)	nagB	1108882..1109586 (-)	705	WP_002995779.1	glucosamine-6-phosphate deaminase	-
SPYM3_RS05640 (SpyM3_1066)	queA	1109788..1110816 (+)	1029	WP_002995782.1	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	-
SPYM3_RS05645 (SpyM3_1067)	-	1110823..1112043 (+)	1221	WP_011054655.1	DUF3114 domain-containing protein	-
SPYM3_RS05650 (SpyM3_1068)	-	1112157..1112747 (-)	591	WP_002983984.1	serine hydrolase	-

Sequence

Protein

• Length: 320 a.a.
• Molecular weight: 37824.21 Da
• Isoelectric Point: 10.2092

>NTDB_id=22797 SPYM3_RS05625 WP_011054653.1 1106788..1107750(-) (coiA) [Streptococcus pyogenes MGAS315]
MTKILTALDGKNQLISLVTQPISTKPPFRCPACKSPVRLRQGTIRRSHFAHVQLAHCQFQAENESEEHLTLKAKLYTSLV
RTEAVCIEKYLPELQQIADLWMNDKLALEIQCSPLPVERLKKRTKAYQEKGYPVRWLLGRKLWLNTHLTALQKQFLYFSS
SLGFHLWELDAAANLLRLKYLIHEDLFGKVSYLTKTISLDHNIMEMFRLPYQQEILYSYQKKMTVNLSKRIQRALLARHP
KWLRRQEKAYLSGYNLLMLTTDAFYPQWRPVQSSSGFCQIEGNLRPYYESFKVYYKKEKDKKVQTLFSPKYYVKMDSNRK

Nucleotide

• Length: 963 bp

>NTDB_id=22797 SPYM3_RS05625 WP_011054653.1 1106788..1107750(-) (coiA) [Streptococcus pyogenes MGAS315]
GTGACAAAAATATTAACCGCTTTAGATGGTAAGAATCAGCTCATTTCGCTAGTAACTCAGCCTATTTCAACGAAACCGCC
TTTTCGTTGCCCAGCTTGCAAATCTCCTGTTCGCTTGCGTCAGGGGACAATTAGACGATCTCATTTTGCCCATGTACAAC
TAGCTCATTGTCAATTCCAAGCAGAAAATGAATCTGAGGAACATTTGACGTTGAAGGCAAAACTTTACACCAGTTTAGTC
CGAACAGAAGCTGTCTGTATTGAAAAATATCTTCCTGAGCTGCAACAGATAGCAGACCTTTGGATGAATGATAAGTTAGC
CTTAGAAATTCAGTGCAGTCCCTTGCCAGTTGAGCGTCTAAAGAAACGCACCAAAGCCTATCAAGAAAAGGGGTATCCGG
TACGATGGTTACTGGGAAGAAAATTGTGGCTTAACACTCACTTAACTGCTTTGCAAAAACAGTTTCTTTACTTTTCATCT
AGTTTGGGCTTTCATTTGTGGGAGCTGGATGCAGCTGCAAATCTGCTACGTCTCAAATATTTAATCCATGAAGACTTATT
TGGTAAGGTAAGTTACCTAACCAAAACCATTTCTTTAGACCACAATATTATGGAAATGTTTCGATTACCCTATCAGCAAG
AAATCCTTTATTCTTATCAGAAAAAAATGACTGTGAACCTATCTAAAAGAATACAAAGAGCTCTTTTAGCTAGACACCCG
AAATGGCTACGACGACAAGAAAAGGCTTACTTATCAGGCTATAATTTACTTATGTTAACAACTGATGCTTTTTATCCTCA
ATGGAGACCAGTTCAATCTTCCAGCGGTTTTTGTCAAATTGAAGGAAATCTTCGCCCTTATTATGAAAGTTTTAAAGTCT
ATTATAAAAAAGAAAAGGATAAGAAGGTGCAAACGCTTTTTTCACCAAAATATTATGTTAAAATGGATAGTAATAGAAAA
TGA

Domains

Predicted by InterProScan.

• Competence protein CoiA-like family (CoiA_nuc) (19-266)

3D structure

• AlphaFold DB: A0A0H2UV79

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus mitis NCTC 12261	42.903	96.875	0.416
coiA	Streptococcus pneumoniae Rx1	41.613	96.875	0.403
coiA	Streptococcus pneumoniae D39	41.613	96.875	0.403
coiA	Streptococcus pneumoniae R6	41.613	96.875	0.403
coiA	Streptococcus pneumoniae TIGR4	41.613	96.875	0.403
coiA	Lactococcus lactis subsp. cremoris KW2	39.024	100	0.4